AGLYCONE

作品数：13被引量：15H指数：2
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相关领域：医药卫生理学更多>>
相关作者：褚晓杰张家宁唐晓波吴春铃朱大岭更多>>
相关机构：黑龙江省生物医药工程重点实验室哈尔滨医科大学陇南师范高等专科学校更多>>
相关期刊：《Chinese Herbal Medicines》《Science China Chemistry》《American Journal of Plant Sciences》《Food and Nutrition Sciences》更多>>
相关基金：国家自然科学基金更多>>
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Therapeutic potential of the citrus flavonoid hesperidin and its aglycone hesperetin against chemotherapy-induced toxicity
《Traditional Medicine Research》2025年第4期31-48,共18页Yu-Su Wang Wei-Jian Chen Zi-Yao Mo Yun-Jing He Ke Nie 
Innovative Team Project of Ordinary Universities in Guangdong Province(No.2022KCXTD016).
Chemotherapy-induced toxicity(CIT)remains a major concern in cancer patients undergoing chemotherapy.New approaches to ameliorate the side effects of chemotherapy are urgently needed.Recently,the nutritional value of ...
关键词：chemotherapy-induced toxicity citrus flavonoids HESPERIDIN HESPERETIN 
葡萄柚提取物柚皮素对运动性心肌损伤中铁死亡的调节作用
《分子植物育种》2024年第17期5825-5833,共9页邵语平 
甘肃省教育科学“十四五”规划课题项目(GS[2021]GHB1829)资助。
葡萄柚(Grapefruit)中含有丰富的无糖体柚皮素(aglycone naringenin,NAR),以其抗氧化、抗炎、抗癌、心血管保护和抗糖尿病的潜在效果而被广泛研究,它可以直接参与多种生物化学途径,调节酶活性和细胞信号传递。本研究旨在探索葡萄柚提取...
关键词：葡萄柚 无糖体柚皮素(aglycone naringenin NAR) 运动性心肌损伤 铁死亡 ROS/GSH/GPX4轴 心肌保护 
Total Synthesis of Starfish Cyclic Steroid Glycosides.Part 1,Synthesis of the Aglycone and Attempts at Installation of the Sugar Units
《Chinese Journal of Chemistry》2023年第8期891-896,共6页Bingfeng Shi Youxi Chen Mingyu Geng Dapeng Zhu Biao Yu 
the financial support from the National Natural Science Foundation of China(21901251);Shanghai Sailing Program(19YF1458400);Laboratory for Marine Drugs and Bioproducts of Qingdao National Laboratory for Marine Science and Technology(LMDBKF201803).
Comprehensive Summary Sepositoside A(1)is the major and first cyclic steroid glycoside isolated from starfishes,which features a strained 16-membered ring formed by tethering C3 and C6 of the steroid aglycone with a l...
关键词：Cyclic starfish glycosides ETHERIFICATION Glycosylation STEROID Total synthesis 
The constitutions of terpenoids and hormones of leaves in red-flesh citrus mutants and their wild types被引量：1
《Horticultural Plant Journal》2022年第3期297-310,共14页Cuihua Liu Min He Juan Xu 
This work was supported by the National Key Research and Development Program(Grant No.2018YFD1000200);the National Natural Science Foundation of China(Grant Nos.31272122,32072530).
To study the profiles and relationships of terpenoids and phytohormones in leaves of red-flesh citrus,we examined four red-flesh mutants that accumulate lycopene in the fruit and their corresponding wild types.We comp...
关键词：CITRUS Carotenoid Terpenoid volatile Limonoid aglycone Hormone Leaf 
Metabolite Profile of Lactic Acid-Fermented Soymilk
《Food and Nutrition Sciences》2018年第11期1327-1340,共14页Maki Kobayashi Tomoyo Shima Mitsuru Fukuda 
Isoflavone aglycone-rich soymilk fermented by Lactobacillus delbrueckii subsp. delbrueckii, strain TUA-4408L (F4408) has stronger lipid metabolism-modulating effects than isoflavone aglycone-poor soymilk fermented by ...
关键词：FERMENTED SOYMILK METABOLITE POLYPHENOL AGLYCONE ORNITHINE 
Phytoestrogen Enriched Tofu from Soybean Meal被引量：1
《American Journal of Plant Sciences》2014年第3期256-261,共6页Su Hyeon Hwang Pushparajah Thavarajah Dilrukshi Thavarajah 
Isoflavone, a group of phytoestrogen, reduces postmenopausal symptoms and the risk of osteoporosis of women. Glycosidic forms of isoflavones are presented in non-fermented soyfoods such as tofu and they are less bioav...
关键词：TOFU Soybean MEAL ISOFLAVONE AGLYCONE DAIDZEIN Genistein 
A New Phenylpropanol Glycoside from Twigs and Leaves of Rhododendron primulaeflorum
《Chinese Herbal Medicines》2012年第2期81-83,共3页Xian-li ZHOU Nai-zhu WU Shuai HUANG Cui-juan WANG You-song WANG Yu ZHANG 
National Natural Science Foundation, China (20872122, 21142004);the New Century Talents Scheme of the Ministry of Education, China(NECT-08-0820);the Fundamental Research Funds for the Central Universities, China (SWJTU2010ZT09);SWJTU Science Research Funds (2008A17)
Objective To study the constituents in the twigs and leaves of Rhododendron primulaeflorum. Methods The constituents were separated and purified with chromatographic methods. Their structures were elucidated by spectr...
关键词：AGLYCONE ERICACEAE 4-hydroxyl-5-methoxyl-phenylpropanol-3-O-β-D-glucopyranoside phenylpropanol glycoside Rhododendron primulaeflorum 
Synthesis analogues of milbemycin and their bioactivity evaluation
《Chinese Chemical Letters》2010年第12期1391-1394,共4页Jin Hao Zhao Ming Hua Ji Xu Hui Xu Jing Li Cheng Guo Nian Zhu 
supported by National Natural Science Foundation of China(No.30700532);the Science and Technology Project of Zhejiang province(No.2008C02007-3).
Eight new 13-O-aminocarbonylivermectin aglycones and 4＇-O-aminocarbonylivermectin monosaccharide were synthesized from ivermectin agiycone and ivermectin monosaccharide by the selective protection of C5-OH group.Thei...
关键词：13-O-Aminocarbonylivermectin aglycone 4＇-O-Aminocarbonylivermectin monosaccharide SYNTHESIS Insecticidal and acaricidal activities 
Virtual Evaluation on Activities of Flavonoids from Scutellaria baicalensis被引量：3
《Chinese Herbal Medicines》2010年第2期136-140,共5页SHANG Qian1,2,LIU Wei2,XU Wei-ren2,LIU Peng2,HAN Ying-mei2,CHEN Cheng-lung3,TANG Li-da2 1.Basic Medical College,Tianjin Medical University,Tianjin 300070,China 2.Tianjin Key Laboratory of Molecular Design and Drug Discovery,Tianjin Institute of Pharmaceutical Research,Tianjin 300193,China 3.Department of Chemistry,National Sun Yat-sen University,Kaohsiung 80424,China 
Ministry of Science and Technology of the PR China (No:2007BAI41B01);Tianjin Municipal Science and Technology Commission (No:07TCZDJC05300)
Objective To explore the investigation method of complicated and profound traditional Chinese herbal medicine,the potential action mechanisms of flavonoids from Scutellaria baicalensis were studied by docking calculat...
关键词：AGLYCONE flavonoid glycoside Scutellaria baicalensis Georgi virtual evaluation 
高浓度的staurosporine aglycone激活大鼠肺动脉平滑肌细胞中的ERK1／2被引量：2
《中国药理学通报》2009年第1期34-38,共5页张家宁 褚晓杰 吕昌莲 吴春铃 包红霞 唐晓波 朱大岭 
国家自然科学基金资助项目(No30370578,30470752,30870904);哈尔滨医科大学青年科学基金资助项目(No060042);东北农业大学博士后课题资助项目(NoLBH-Z06168);哈尔滨医科大学医学基础学科创新群体基金资助项目
目的有报道表明staurosporine作为一种蛋白激酶C（PKC）的抑制剂，可以在多种细胞系内调节细胞外信号调节激酶（ERK1／2）的活性，但是它的衍生物staurosporineagly—COfle（SA）是否具有相同的作用还不清楚，本次实验旨在阐明其对ERK1...
关键词：STAUROSPORINE aglycone(SA) 细胞外信号调节激酶 蛋白激酶C 蛋白激酶A 
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