HEPATOPROTECTION

作品数:48被引量:134H指数:6
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相关领域:医药卫生更多>>
相关期刊:《Asian Pacific Journal of Tropical Biomedicine》《Journal of Traditional Chinese Medicine》《Chinese Herbal Medicines》《Chinese Journal of Natural Medicines》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划更多>>
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Mechanistic Insights into N-Oleoylethanolamide-Mediated Hepatoprotection via PPAR-α
《BIOCELL》2025年第4期607-627,共21页Darya Ivashkevich Arina Ponomarenko Igor Manzhulo Inessa Dyuizen 
supported by the Russian Science Foundation(project 24-75-00072).
The high prevalence of obesity and associated nonalcoholic fatty liver disease(NAFLD)in the population determines the increased interest in identifying molecular targets for regulating the processes underlying these p...
关键词:NAFLD liver inflammation N-Oleoylethanolamide OEA PPAR-Α 
Bioactivity and Molecular Mechanism of Bilobalide
《Asian Agricultural Research》2025年第2期34-37,共4页Junhao LI Xichun HUANG Quan QUAN Mingxinzhi WANG Jingchao WANG Chenghao JIN 
Supported by Heilongjiang Provincial Key Research and Development Plan Guidance Project(GZ20220039);Central Government Supports Local College Reform and Development Fund Talent Training Projects(2020GSP16).
Ginkgo biloba is a deciduous tree belonging to Ginkgo,Ginkgoaceae.It is often used to treat dizziness,tinnitus,vertigo,hyperlipidemia and diabetic peripheral neuropathy.Bilobalide is a natural active compound derived ...
关键词:BILOBALIDE ANTI-INFLAMMATORY Obesity treatment NEUROPROTECTION HEPATOPROTECTION 
Lignans are the main active components of Schisandrae Chinensis Fructus for liver disease treatment:a review
《Food Science and Human Wellness》2024年第5期2425-2444,共20页Ke Fu Shu Dai Cheng Ma Yafang Zhang Shenglin Zhang Cheng Wang Lihong Gong Honglin Zhou Yunxia Li 
supported by National Natural Science Foundation of China(81891012,U19A2010,81630101);Sichuan Province Science and Technology Support Program(2021JDRC0041);Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine(ZYYCXTD-D-202209).
As a traditional Chinese herbal medicine,Schisandrae Chinensis Fructus(SC)has been used in medicine and food industry due to its health care and therapeutic effects.Over the past 20 years,the use of SC and its active ...
关键词:Schisandrae Chinensis Fructus Lignans HEPATOPROTECTION Pharmacological effects Molecular mechanism 
Peroxisome proliferator-activated receptor agonists:A new hope towards the management of alcoholic liver disease
《World Journal of Gastroenterology》2024年第35期3965-3971,共7页Siva Sundara Kumar Durairajan Abhay Kumar Singh Ashok Iyaswamy 
In this editorial,we examine a paper by Koizumi et al,on the role of peroxisome proliferator-activated receptor(PPAR)agonists in alcoholic liver disease(ALD).The study determined whether elafibranor protected the inte...
关键词:Alcoholic liver disease Peroxisome proliferator-activated receptors Peroxisome proliferator-activated receptors agonists Liver fibrosis INFLAMMATION Metabolic regulation HEPATOPROTECTION 
Bioactive components,pharmacological properties and underlying mechanism of Ganoderma lucidum spore oil:A review被引量:2
《Chinese Herbal Medicines》2024年第3期375-391,共17页Jianying Liu Binzhi Zhang Leqi Wang Shasha Li Qinqiang Long Xue Xiao 
supported by Pearl River S&T Nova Program of Guangzhou(No.201610010113);the Open Research Fund of NMPA Key Laboratory for Rapid Testing Technology of Drugs,Guangdong Institute for Drug Control(No.KF2022002,KF2022006);Research Project of Chinese Medicine in TCM Bureau of Guangdong Province(No.20231202).
Ganoderma lucidum is a Chinese medicinal fungus with a long history of use in healthcare and disease treatment.G.lucidum spores(GLS)are tiny germ cells released from the mushroom cap during the mature stage of growth....
关键词:ANTI-AGING ANTI-TUMOR bioactive components Ganoderma lucidum spore oil HEPATOPROTECTION immune regulation pharmacological properties 
Research progress in the study of Clinacanthus nutans and treatment of liver diseases
《TMR Modern Herbal Medicine》2024年第1期26-33,共8页Qian-Jin Fu Sheng-Gang Sang 
the Social Development Project And Natural Science Foundation of Hainan Province(No.ZDYF2019139 and No.ZDYF2023SHFZ116).
Background:Based on the long history of medicinal value and modern pharmacological research,a systematic collation of the Clinacanthus nutans has been carried out with a view to providing useful references for the cli...
关键词:Clinacanthus nutans active ingredients mechanisms of action HEPATOPROTECTION 
Curcumin alleviates lipid deposition in hepatocytes through miR-3666/AMPK axis regulation
《Food Bioscience》2023年第3期637-644,共8页Hengju Ge Jiaxin Li Yang Xu Jiahong Xie Naymul Karim Fujie Yan Jianling Mo Wei Chen 
supported by grants from Zhejiang Provincial Key R&D Program of China(2021C02018);National Natural Science Foundation of China(32172192).
Curcumin(CUR),the main compound extracted from Curcuma longa,has various biological actions,including hepatoprotective,anti-infective,anti-inflammatory,antioxidant,and neurotrophic properties.But it has not yet been c...
关键词:CURCUMIN Lipid deposition MiR-3666 AMPK pathways HEPATOPROTECTION 
SIRT1 activation synergizes with FXR agonism in hepatoprotection via governing nucleocytoplasmic shuttling and degradation of FXR被引量:4
《Acta Pharmaceutica Sinica B》2023年第2期559-576,共18页Shuang Cui Huijian Hu An Chen Ming Cui Xiaojie Pan Pengfei Zhang Guangji Wang Hong Wang Haiping Hao 
supported by the National Natural Science Foundation of China(grants 81720108032 and 81930109 to Haiping Hao,82073926 to Hong Wang,and 82073928 to Guangji Wang);the National Key Research and Development Programme of China(2021YFA1301300 to Haiping Hao);Leading Technology Foundation Research Project of Jiangsu Province(grant BK20192005 to Guangji Wang,China);the Project Program of State Key Laboratory of Natural Medicines(China Pharmaceutical University,SKLNMZZ202202 to Haiping Hao);Sanming Project of Medicine in Shenzhen(SZSM201801060 to Guangji Wang,China)。
Farnesoid X receptor(FXR)is widely accepted as a promising target for various liver diseases;however,panels of ligands in drug development show limited clinical benefits,without a clear mechanism.Here,we reveal that a...
关键词:FXR Nuclear receptor ACETYLATION PHOSPHORYLATION Nucleocytoplasmic shuttling DEGRADATION Nonalcoholic steatohepatitis Combinatorial drugs 
Particle Size Effects on Antioxydant and Hepatoprotective Potential of Essential Oil from Eucalyptus camaldulensis Leaves against Carbon Tetrachloride-Induced Hepatotoxicity in Rats
《Pharmacology & Pharmacy》2022年第8期253-272,共20页Venant Donald Noumi Markusse Deli Richard Marcel Nguimbou Elie Baudelaire Sandrine Rup-Jacques Dicko Amadou Selestin Sokeng Nicolas Yanou Njintang 
Particle size fractionation by sieving is used to optimize antioxydant potential of natural substances. The aim of the present study was to evaluate particle size effects on antioxidant and hepatoprotective potential ...
关键词:Eucalyptus camaldulensis Powder Particle Size Essential Oils HEPATOPROTECTION Oxidative Stress 
Phenolic compounds and hepatoprotective potential of Anastatica hierochuntica ethanolic and aqueous extracts against CCl4-induced hepatotoxicity in rats被引量:4
《Journal of Traditional Chinese Medicine》2020年第6期947-955,共9页Hassan Barakat Tariq I.Almundarij 
OBJECTIVE:To investigate the effect of Anastatica hierochuntica ethanolic(KEE),aqueous(KAE)extracts,and their combination against CCl4-induced hepatotoxicity in rats.METHODS:The HPLC analysis for KEE and KAE was quant...
关键词:Phenolic compounds Anastatica hierochuntica Liver markers Antioxidant enzymes HEPATOPROTECTION 
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