ECHINACOSIDE

作品数：12被引量：72H指数：6
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相关领域：医药卫生更多>>
相关作者：成聪王钊张弛朱慧汪玉馨更多>>
相关机构：中国药科大学北京市结核病胸部肿瘤研究所清华大学更多>>
相关期刊：《Traditional Medicine Research》《Journal of Traditional Chinese Medicine》《Chinese Herbal Medicines》《Medicinal Plant》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划更多>>
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Echinacoside attenuates glandular fibrosis in benign prostatic hyperplasia via inhibiting MKK6/MK2 signaling pathway被引量：1
《Traditional Medicine Research》2024年第3期24-31,共8页Si Qin Jing-Lou Chen Xiao-Feng Zhou Cong-Yue Xu Jing Guo 
supported by the Research Fund of Jianghan University(grant number 2023KJZX23).
Background:Lower urinary tract symptoms commonly occur in the elderly population and seriously constrain the quality of life.Glandular fibrosis is an important pathobiological process in benign prostatic hyperplasia a...
关键词：benign prostatic hyperplasia ECHINACOSIDE epithelial-mesenchymal transition FIBROSIS 
Efficacy of verbascoside,echinacoside,crenatoside on altitudeinduced fatigue in rats and possible mechanism被引量：1
《Journal of Traditional Chinese Medicine》2023年第5期934-943,共10页GUO Ziliang QIAN Qingyuan LI Xiaolin ZHU Yuting REN Jun LI Maoxing 
Logistics Research Projects:the Project of Preparation of Crocetin Nanoparticles and Study on the Mechanism of Enhancing the Efficiency of Military Operations at High Altitude(CLB21J036);Top Cultivation Project:the Role of Crocetin in Improving Military Operations Efficiency in High Altitude Hypoxic Environments(2021yxky001);Youth Cultivation Project:Screening and Mechanism Study of Phenylethanol Glycosides and Their Metabolites Against High Altitude Hypoxia Activity(2021yxky060);Open Fund Project of the Collaborative Innovation Center Jointly Constructed by the Northwest China Tibet Medicine Province and Ministry:the Open Foundation of Northwest Collaborative Innovation Center for Traditional Chinese Medicine Co-constructed by Gansu Province and MOE of PRC(Xbzzy-2022-06);Gansu Provincial Health Industry Research Project:Study on the Anti-Hypoxia and Anti-fatigue Effects and Mechanisms of Crocin(GSWSKY2020-41);National Youth Fund:Study on the Dual Regulation of Vascular Endothelial Homeostasis Based on the PI3K/Akt Pathway-the Mechanism of Action of Zmyristosterone against Ischemic Stroke(82003982)。
OBJECTIVE:To study the efficacy and mechanism of three phenylethanoid glycosides(PhG s)(verbascoside,echinacoside,and crenatoside)on altitude-induced fatigue in rats.METHODS:Altitude-induced fatigue model rats were es...
关键词：phenylethanoid glycosides VERBASCOSIDE HYPOXIA FATIGUE energy metabolism 
Content Determination of Cistanches Herba in Zhenrongdan Mixture by HPLC
《Medicinal Plant》2022年第5期4-7,共4页Jianping ZHANG Xuemei ZHOU Han GAO Dong WANG 
[Objectives]To establish a HPLC-UV method for the determination of Cistanches Herba in Zhenrongdan mixture.[Methods]According to the content determination method of Cistanches Herba in the 2020 edition of Chinese Phar...
关键词：HPLC-UV Zhenrongdan mixture Cistanches Herba ECHINACOSIDE 
Echinacoside Alleviates Cognitive Impairment in Cerebral Ischemia Rats through α7nAChR-Induced Autophagy被引量：6
《Chinese Journal of Integrative Medicine》2022年第9期809-816,共8页DING Ling YE Hong GU Long-dian DU An-qing YUAN Xin-lu 
Supported by Talents Training Program of Pudong Hospital Affiliated to Fudan University(No.PX202007)。
Objectives:To evaluate the effect of echinacoside(ECH)on cognitive dysfunction in post cerebral stroke model rats.Methods:The post stroke cognitive impairment rat model was created by occlusion of the transient middle...
关键词：cerebral ischemia cognitive impairment AUTOPHAGY ECHINACOSIDE cholinergic activity 
Preliminary optimization of a Chinese herbal medicine formula based on the neuroprotective effects in a rat model of rotenone-induced Parkinson's disease被引量：8
《Journal of Integrative Medicine》2018年第4期290-296,共7页Xu-xia Bao Hui-han Ma Hao Ding Wen-wei Li Min Zhu 
supported by grants from Shanghai Scientific and Technical Supporting Program of China(No.12401901003);Shanghai Three-Year Action Plan to Further Accelerate the Development of Traditional Chinese Medicine(No.ZY3-CCCX-1-1015);the National Natural Science Foundation(No.NSFC81400393)
Objective： The main objective of this study was to preliminarily determine the optimum formulation of a Chinese herbal formula that may have neuroprotective effects against rotenone-induced Parkinson＇s disease （PD...
关键词：Parkinson＇s disease Rotenone Chinese herb Echinacoside Uniform design 
Echinacoside and Cistanche tubulosa(Schenk) R. wight have male reproductive protection effect by targeting hypothalamic and rogen receptor被引量：2
《中国药理学与毒理学杂志》2018年第4期257-258,共2页Xiao-ying ZHANG Zhi-hui JIANG Xue-mei CHANG Rui-min CAO 
supported by the National Key Research and Development Program of China(2017YFD0501400)
OBJECTIVE Cistanche deserticola Y.C.Ma is an official plant that grows in arid or semi-arid areas.Our early work demonstrated that Cistanche extracts protect against sperm damage in mice under bisphenol A induced repr...
关键词：肉苁蓉 植物 类固醇 药物分析 
Application of ~1H NMR-based metabolomics for discrimination of different parts and development of a new processing workflow for Cistanche deserticola被引量：8
《Acta Pharmaceutica Sinica B》2017年第6期647-656,676,共11页Pingping Zou Yuelin Song Wei Lei Jun Li Pengfei Tu Yong Jiang 
financially supported by National Natural Science Foundation of China (Nos. 81222051 and 81403073);Quality Guarantee System of Chinese Herbal Medicines (No. 201507002);International Quality Standards R&D Program of Traditional Chinese Medicine (No. 201307002)
Cistanche deserticola(CD) is one of the two authoritative source plants of Cistanches Herba, a well-known medicinal plant. Herein,~1H NMR spectroscopy was employed to characterize the chemical profile and to distingui...
关键词：Cistanche deserticola 1H NMR-based metabolomics Processing workflow Different parts Phenylethanoid glycoside Tricarboxylic acid cycle metabolites ECHINACOSIDE ACTEOSIDE 
Echinacoside Protects Against MPP+-Induced Neuronal Apoptosis via ROS/ATF3/CHOP Pathway Regulation被引量：19
《Neuroscience Bulletin》2016年第4期349-362,共14页Qing Zhao Xiaoyan Yang Dingfang Cai Ling Ye Yuqing Hou Lijun Zhang Jiwei Cheng Yuan Shen Kaizhe Wang Yu Bai 
supported by the National Natural Science Foundation of China(81202814);the Shanghai Municipal Commission of Health and Family Planning(20124y116);the Young Teachers Training Funding Scheme of Shanghai Colleges and Universities,China(zzszy12026)
Echinacoside （ECH） is protective in a mouse model of Parkinson＇ s disease （PD） induced by 1-methyl-4- phenylpyridinium ion （MPP＋）. To investigate the mechanisms involved, SH-SYSY neuroblastoma ceils were treat...
关键词：ECHINACOSIDE Parkinson＇s disease 1-Methyl-4-phenylpyridinium ion. Reactive oxygen species ATF3 CHOP 
Echinacoside induces rat pulmonary artery vasorelaxation by opening the NO-cGMP-PKG-BKca channels and reducing intracellular Ca2＋ levels被引量：13
《Acta Pharmacologica Sinica》2015年第5期587-596,共10页Xiang-yun GAI Yu-hai WEI Wei ZHANG Ta-na WUREN Ya-ping WANG Zhan-qiang LI Shou LIU Lan MA Dian-xiang LU Yi ZHOU Ri-li GE 
Aim： Sustained pulmonary vasoconstriction as experienced at high altitude can lead to pulmonary hypertension （PH）. The main purpose of this study is to investigate the vasorelaxant effect of echinacoside （ECH）, a...
关键词：Tibetan herb ECHINACOSIDE pulmonary hypertension high altitude VASORELAXATION NO BKCA K^R artery ring pulmonaryarterial smooth muscle cells 
Prevention of Cistanche salsa Extract on Hepatic Fibrosis Induced by Carbon Tetrachloride in Rats被引量：10
《Chinese Herbal Medicines》2013年第3期199-204,共7页YANG Feng-rui WEN Du-su FANG Bu-wu LOU Jian-shi MENG Lin 
Grants from Tianjin Medical University;China(2009ky42)
Objective To explore the antifibrotic effect of echinacoside on carbon tetrachloride(CCl4)-induced hepatic fibrosis in rats.Methods Male Wistar rats were randomly divided into normal control(n = 8),model(n = 14),and e...
关键词：carbon tetrachloride ECHINACOSIDE extracellular matrix hepatic fibrosis lipid peroxidation 
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