为探究des(rhamnosyl)verbascoside体外抗乙型肝炎病毒(HBV)的活性作用和机制,本研究以des(rhamnosyl)verbascoside为实验药物对HepG2.2.15细胞进行干预,实验分为药物干预组和对照组,采用串联质谱标签(Tandem Mass Tag,TMT)蛋白质组学...
Special Funds for LOCAL SCIENce and Technology Development Guided by the Central Government(No.ZYD2022C17);National Natural Science Foundation of China(No.82160232)。
Objective:To explore the improving effect of verbascoside on Parkinson's disease(PD)model mice and to clarify the possible mechanism.Methods:60 C57BL/6 male mice were randomly divided into normal group,model group,low...
supported by the Tianjin Science and Technology Project(21ZYJDJC00080)and(20ZYJDJC00120);the Natural Science Foundation of Tianjin(18JCZDJC97700);the Natural Science Foundation of China(81573547).
Verbascoside,abundant in olive mill wastewater,is a phenylethanolic glycoside with a wide range of pharmacological activities.Atherosclerosis(AS)is a common metabolic disease and abnormal lipid metabolism in liver is ...
Logistics Research Projects:the Project of Preparation of Crocetin Nanoparticles and Study on the Mechanism of Enhancing the Efficiency of Military Operations at High Altitude(CLB21J036);Top Cultivation Project:the Role of Crocetin in Improving Military Operations Efficiency in High Altitude Hypoxic Environments(2021yxky001);Youth Cultivation Project:Screening and Mechanism Study of Phenylethanol Glycosides and Their Metabolites Against High Altitude Hypoxia Activity(2021yxky060);Open Fund Project of the Collaborative Innovation Center Jointly Constructed by the Northwest China Tibet Medicine Province and Ministry:the Open Foundation of Northwest Collaborative Innovation Center for Traditional Chinese Medicine Co-constructed by Gansu Province and MOE of PRC(Xbzzy-2022-06);Gansu Provincial Health Industry Research Project:Study on the Anti-Hypoxia and Anti-fatigue Effects and Mechanisms of Crocin(GSWSKY2020-41);National Youth Fund:Study on the Dual Regulation of Vascular Endothelial Homeostasis Based on the PI3K/Akt Pathway-the Mechanism of Action of Zmyristosterone against Ischemic Stroke(82003982)。
OBJECTIVE:To study the efficacy and mechanism of three phenylethanoid glycosides(PhG s)(verbascoside,echinacoside,and crenatoside)on altitude-induced fatigue in rats.METHODS:Altitude-induced fatigue model rats were es...
supported by the National Key Research and Development Program(2019YFA0905703);the National Natural Science Foundation of China(31970065,U1902214);the Tianjin Synthetic Biotechnology Innovation Capacity Improvement Project(TSBICIPKJGG-002);the Key Research and Development Plan of Guangdong Province(2022B1111070005).
Verbascoside,which was first discovered in 1963,is a well-known phenylethanoid glycoside(PhG)that exhibits antioxidant,anti-inflammatory,antimicrobial,and neuroprotective activities and contributes to the therapeutic ...
Non-alcoholic fatty liver disease(NAFLD)includes a broad spectrum of liver dysfunction ranging from hepatic steatosis(intracellular triglyceride accumulation)to steatohepatitis.This study investigated the beneficial e...
Cancer is a set of diseases including abnormal growth of cells that can spread to another tissue. Verbascoside (or acteoside) is a naturally occurring, water-soluble secondary metabolite with significant biological pr...
supported by a grant from Science and Technology Support Traditional Chinese Drug Research and Development Project of Shanghai of China,No.12401900302;Traditional Chinese Medicine Research Foundation of Shanghai Municipal Health Bureau of China,No.2012J009A;a grant from Annual Research Budget of Shanghai University of Traditional Chinese Medicine of China in 2013,No.2013JW25;the National Natural Science Foundation of China,No.30672684;30973722
Tyrosine hydroxylase is a key enzyme in dopamine biosynthesis. Change in tyrosine hydroxylase expression in the nigrostriatal system is closely related to the occurrence and development of Parkinson's disease. Verbas...
financially supported by Food and Health Bureau HKSAR,Health and Health Services Research Fund no.11120831
Myotoxicity is a well-known side effect of statins,the common lipid-lowering drug.Herba Cistanches(HC,Cistanche deserticola)is a Chinese herb traditionally used for muscle problems.Recent studies demonstrated that HC ...
The chemical characterization of phenolic extracts of salad burnet (Sanguisorba minor Scop. s.l.) and broomrape (Orobanche crenata Forsk.) was performed. Active fractions were separated and characterized and, in the c...