Supported by Tianjin Key Medical Discipline(Specialty)Construction Project(No.TJYXZDXK-037A).
AIM:To explore the therapeutic effect and main molecular mechanisms of acteoside in a glaucoma model in DBA/2J mice.METHODS:Proteomics was used to compare the differentially expressed proteins of C57 and DBA/2J mice.A...
supported by the National Key Research and Development Program(2019YFA0905703);the National Natural Science Foundation of China(31970065,U1902214);the Tianjin Synthetic Biotechnology Innovation Capacity Improvement Project(TSBICIPKJGG-002);the Key Research and Development Plan of Guangdong Province(2022B1111070005).
Verbascoside,which was first discovered in 1963,is a well-known phenylethanoid glycoside(PhG)that exhibits antioxidant,anti-inflammatory,antimicrobial,and neuroprotective activities and contributes to the therapeutic ...
Research project of Heilongjiang Provincial Health Commission(2017-389);The Interdisciplinary program of Jiamusi University(12J201504);Innovation and Entrepreneurship training program for college students in Heilongjiang Province(201910222070);Project of Heilongjiang Provincial Health Department(2014-241);Innovation and Entrepreneurship training program for college students in Jiamusi University(2015XJ06);The Key project of Science and Technology of Jiamusi University(12Z1201506);Excellent innovation team construction project of basic scientific research business fees of provincial colleges and universities in Heilongjiang Province in 2019.
Objective:To investigate the neuroprotective effect and mechanism of Acteoside(AC)on brain injury in epileptic rats.Methods:30 Sprague-Dawlay rats(SPF grade,healthy males,about 200g)were randomly divided into epilepsy...
supported financially by the National Natural Science Foundation of China(Nos.31370967 and 31170919);the Guangdong Province Universities and Colleges Pearl River Scholar Funded Scheme(2014);the Science and Technology Planning Project of Guangdong Province(No.2015A020212033);the Science and Technology Project of Guangzhou(No.201805010002);the Innovation Project of Graduate School of South China Normal University(No.2018LKXM019)。
Developing new drugs to treat Parkinson's disease efficiently is challenging. Here we report that chitosan nanoparticles(APPDNs) could serve as novel candidates for the design of anti-PD drugs. In this study, we inves...
Supported by Natural Science Foundation of Jiangsu Province(BK20151283);Science Program of Lianyungang(CG1612);521 Talent Project of Lianyungang;Jiangsu Provincial Practice Innovation Training Program for Undergraduate
In this study, bioassay-guided isolation, identification and biological evaluation of antioxidant components from total flavonoids of Chinese herbal plant Mimenghua were performed. 1, 1-Diphenyl-2-picrylhydrazyl(DPPH)...
financially supported by National Natural Science Foundation of China (Nos. 81222051 and 81403073);Quality Guarantee System of Chinese Herbal Medicines (No. 201507002);International Quality Standards R&D Program of Traditional Chinese Medicine (No. 201307002)
Cistanche deserticola(CD) is one of the two authoritative source plants of Cistanches Herba, a well-known medicinal plant. Herein,~1H NMR spectroscopy was employed to characterize the chemical profile and to distingui...
supported by special funds for scientific research institution innovation and development in the Xinjiang Uygur Autonomous Region of China(No.2014003)
Acteoside(verbascoside), a phenylethanoid glycoside widely distributed in various plants, has been shown to have potential activity against Alzheimer's disease, attracting great attentions recently. The present study ...
National Key Technology R&D Program "New Drug Innovation" of China (Grant No. 2009ZX 09308-004,2009ZX09311-004,2012ZX09301002-002)
A sensitive RP-HPLC-DAD method has been developed and validated for the determination of luteolin and acteoside in the herb ofSiphonostegia chinensis Benth. (Siphonostegiae Herba). Separation was achieved on an Agil...
Supported by the National Natural Science Foundation of China(No.30873364);the Natural Science Foundation of Jilin Province of China(Nos.20071102 and 2008-167)
Two phenylethanoid glycosides(PhGs), plantamajoside and acteoside, were isolated and purified from the aerial parts ofPlantago asiatica for the first time by high performance centrifugal partition chromatography(HP...