ACTEOSIDE

作品数:19被引量:83H指数:5
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相关作者:朱大元尚雁君蒋山好李医明廖矛川更多>>
相关机构:中国科学院第二军医大学复旦大学上海市计划生育科学研究所更多>>
相关期刊:《杨凌职业技术学院学报》《Chinese Journal of Natural Medicines》《International Journal of Ophthalmology(English edition)》《新乡医学院学报》更多>>
相关基金:国家自然科学基金国家杰出青年科学基金国家科技支撑计划更多>>
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Neuroprotective effects of acteoside in a glaucoma mouse model by targeting Serta domain-containing protein 4
《International Journal of Ophthalmology(English edition)》2024年第4期625-637,共13页Hui-Jie Hao Ya-Hong Li Bo Yu Xun Liu Yan Zhang Xiao-Li Xing 
Supported by Tianjin Key Medical Discipline(Specialty)Construction Project(No.TJYXZDXK-037A).
AIM:To explore the therapeutic effect and main molecular mechanisms of acteoside in a glaucoma model in DBA/2J mice.METHODS:Proteomics was used to compare the differentially expressed proteins of C57 and DBA/2J mice.A...
关键词:GLAUCOMA ACTEOSIDE Serta domaincontaining protein 4 PROTEOMICS MICE 
Complete biosynthesis of the phenylethanoid glycoside verbascoside被引量:3
《Plant Communications》2023年第4期286-300,共15页Yihan Yang Daoyi Xi Yanan Wu Tao Liu 
supported by the National Key Research and Development Program(2019YFA0905703);the National Natural Science Foundation of China(31970065,U1902214);the Tianjin Synthetic Biotechnology Innovation Capacity Improvement Project(TSBICIPKJGG-002);the Key Research and Development Plan of Guangdong Province(2022B1111070005).
Verbascoside,which was first discovered in 1963,is a well-known phenylethanoid glycoside(PhG)that exhibits antioxidant,anti-inflammatory,antimicrobial,and neuroprotective activities and contributes to the therapeutic ...
关键词:ACYLTRANSFERASE cytochrome P450 microbial synthesis VERBASCOSIDE ACTEOSIDE PHENYLPROPANOID 
Brain protection of AC in PTZ-induced epileptic rats
《Journal of Hainan Medical University》2020年第24期1-4,共4页Jing Li Hai-Bo Yu Qing Xue Hai-Tao Yu Li-Hua Wang Wei-Qun Wang 
Research project of Heilongjiang Provincial Health Commission(2017-389);The Interdisciplinary program of Jiamusi University(12J201504);Innovation and Entrepreneurship training program for college students in Heilongjiang Province(201910222070);Project of Heilongjiang Provincial Health Department(2014-241);Innovation and Entrepreneurship training program for college students in Jiamusi University(2015XJ06);The Key project of Science and Technology of Jiamusi University(12Z1201506);Excellent innovation team construction project of basic scientific research business fees of provincial colleges and universities in Heilongjiang Province in 2019.
Objective:To investigate the neuroprotective effect and mechanism of Acteoside(AC)on brain injury in epileptic rats.Methods:30 Sprague-Dawlay rats(SPF grade,healthy males,about 200g)were randomly divided into epilepsy...
关键词:EPILEPSY ACTEOSIDE EEG Learning and Memory Brain Protection 
苯丙素苷Acteoside,Isoacteoside和Ligupurpuroside J的全合成
《高等学校化学学报》2020年第8期1708-1720,共13页胡志飞 徐鹏 魏炳成 俞飚 
国家自然科学基金(批准号:21621002);王宽诚率先人才计划资助。
发展了一条合成苯丙素苷类化合物的通用路线,并依据此路线完成了苯丙素苷毛蕊花糖苷(Acteoside)和异毛蕊花糖苷(Isoacteoside)的全合成及紫茎女贞苷J(Ligupurpuroside J)的首次全合成.其中的关键步骤是应用金(Ⅰ)催化的鼠李糖邻炔基苯...
关键词:苯丙素苷 毛蕊花糖苷 异毛蕊花糖苷 紫茎女贞苷J 糖苷化反应 
Neuroprotective effect of chitosan nanoparticle gene delivery system grafted with acteoside (ACT) in Parkinson's disease models被引量:1
《Journal of Materials Science & Technology》2020年第8期197-207,共11页Yongyong Xue Na Wang Zhi Zeng Jinpeng Huang Zhiming Xiang Yan-Qing Guan 
supported financially by the National Natural Science Foundation of China(Nos.31370967 and 31170919);the Guangdong Province Universities and Colleges Pearl River Scholar Funded Scheme(2014);the Science and Technology Planning Project of Guangdong Province(No.2015A020212033);the Science and Technology Project of Guangzhou(No.201805010002);the Innovation Project of Graduate School of South China Normal University(No.2018LKXM019)。
Developing new drugs to treat Parkinson's disease efficiently is challenging. Here we report that chitosan nanoparticles(APPDNs) could serve as novel candidates for the design of anti-PD drugs. In this study, we inves...
关键词:Parkinson's disease Chitosan nanoparticles ACTEOSIDE Gene therapy PDNA 
Isolation and Identification of Antioxidative Active Component from Total Flavonoids of Mimenghua被引量:1
《Agricultural Science & Technology》2017年第4期719-723,共5页Jiacai GUO Bing HU Lei GUO 
Supported by Natural Science Foundation of Jiangsu Province(BK20151283);Science Program of Lianyungang(CG1612);521 Talent Project of Lianyungang;Jiangsu Provincial Practice Innovation Training Program for Undergraduate
In this study, bioassay-guided isolation, identification and biological evaluation of antioxidant components from total flavonoids of Chinese herbal plant Mimenghua were performed. 1, 1-Diphenyl-2-picrylhydrazyl(DPPH)...
关键词:Mimenghua Total flavonoids Antioxidant activity Isolation and identification ACTEOSIDE 
Application of ~1H NMR-based metabolomics for discrimination of different parts and development of a new processing workflow for Cistanche deserticola被引量:8
《Acta Pharmaceutica Sinica B》2017年第6期647-656,676,共11页Pingping Zou Yuelin Song Wei Lei Jun Li Pengfei Tu Yong Jiang 
financially supported by National Natural Science Foundation of China (Nos. 81222051 and 81403073);Quality Guarantee System of Chinese Herbal Medicines (No. 201507002);International Quality Standards R&D Program of Traditional Chinese Medicine (No. 201307002)
Cistanche deserticola(CD) is one of the two authoritative source plants of Cistanches Herba, a well-known medicinal plant. Herein,~1H NMR spectroscopy was employed to characterize the chemical profile and to distingui...
关键词:Cistanche deserticola 1H NMR-based metabolomics Processing workflow Different parts Phenylethanoid glycoside Tricarboxylic acid cycle metabolites ECHINACOSIDE ACTEOSIDE 
Pharmacokinetics of acteoside following single dose intragastric and intravenous administrations in dogs被引量:5
《Chinese Journal of Natural Medicines》2015年第8期634-640,共7页ZHANG Wei HUO Shi-Xia WEN Yan-Li XING Han ZHANG Qing LI Ning ZHAO Di SUN Xiao-Lin XU Jie YAN Ming CHEN Xi-Jing 
supported by special funds for scientific research institution innovation and development in the Xinjiang Uygur Autonomous Region of China(No.2014003)
Acteoside(verbascoside), a phenylethanoid glycoside widely distributed in various plants, has been shown to have potential activity against Alzheimer's disease, attracting great attentions recently. The present study ...
关键词:ACTEOSIDE LC—MS/MS BEAGLE DOG BIOAVAILABILITY 
Determination of luteolin and acteoside in Siphonostegiae Herba by high-performance liquid chromatography被引量:1
《Journal of Chinese Pharmaceutical Sciences》2012年第4期333-337,共5页赵明波 魏荷琳 李军 屠鹏飞 
National Key Technology R&D Program "New Drug Innovation" of China (Grant No. 2009ZX 09308-004,2009ZX09311-004,2012ZX09301002-002)
A sensitive RP-HPLC-DAD method has been developed and validated for the determination of luteolin and acteoside in the herb ofSiphonostegia chinensis Benth. (Siphonostegiae Herba). Separation was achieved on an Agil...
关键词:Siphonostegiae Herba Siphonostegia chinensis Benth. LUTEOLIN ACTEOSIDE HPLC-DAD 
Isolation and Purification of Plantamajoside and Acteoside from Plant Extract of Plantago asiatica L. by High Performance Centrifugal Partition Chromatography被引量:3
《Chemical Research in Chinese Universities》2009年第6期817-821,共5页LI Li LIU Chun-ming CHEN Zhao-jie WANG Jing SHI Dong-fang LIU Zhi-qiang 
Supported by the National Natural Science Foundation of China(No.30873364);the Natural Science Foundation of Jilin Province of China(Nos.20071102 and 2008-167)
Two phenylethanoid glycosides(PhGs), plantamajoside and acteoside, were isolated and purified from the aerial parts ofPlantago asiatica for the first time by high performance centrifugal partition chromatography(HP...
关键词:Plantago asiatica L Plantamajoside ACTEOSIDE HPCPC ESI-MS HPLC-DAD 
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