云南高校图书馆联盟文献共享服务平台- GLUTAMINASE

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Structural basis for activation and filamentation of glutaminase: 《Cell Research》2024年第1期76-79,共4页Chen-Jun Guo Zi-Xuan Wang Ji-Long Liu; supported by the Ministry of Science and Technology of China(2021YFA0804700);the National Natural Science Foundation of China(31771490);Shanghai Science and Technology Commission(20JC1410500);UK Medical Research Council(MC_UU_12021/3,MC_U137788471)to J.L.L.; Dear Editor,Glutaminase catalyzes the first step of glutamine metabolism,converting glutamine to glutamate,which enters the tricarboxylic acid cycle.In human,glutaminase is encoded by two different genes,GLS1 and GLS2...; 关键词：METABOLISM KIDNEY ACTIVATION

Microglial glutaminase 1 mediates chronic restraint stress-induced depression-like behaviors and synaptic damages: 《Signal Transduction and Targeted Therapy》2024年第1期40-43,共4页Huili Chen Shengyang Fu Xiangyu Li Meng Shi Jiazhen Qian Shu Zhao Ping Yuan Lu Ding Xiaohuan Xia Jialin C.Zheng; supported in part by research grants from the National Natural Science Foundation of China(Nos.91949204 and 81830037 to J.C.Z.,Nos.81971145 and 82271477 to X.X.);Independent Original Basic Research Program of Tongji University(No.22120220596 to X.X.).; Dear Editor,Major depressive disorder(MDD)is one of the most common psychiatric illnesses that significantly increase the risk of suicide.1 Stress-triggered dysfunctions of microglia have been identified as a commonly...; 关键词：INVOLVEMENT INFLAMMATION media

Corrigendum to “Combination of microwave heating and transglutaminase cross-linking enhances the stability of limonene emulsion carried by whey protein isolate” [Food Bioscience 47 (2022) 101684]: 《Food Bioscience》2022年第6期1346-1346,共1页Akhunzada Bilawal Xindi Wang Kwang-Chol Oh Abdul Qayum Munkh-Amgalan Gantumur Zhanmei Jiang Juncai Hou

Alteration of mitochondrial protein succinylation against cellular oxidative stress in cancer被引量：1: 《Military Medical Research》2022年第5期637-638,共2页Jing Zhang Zi-Qin Han Yang Wang Qing-Yu He; the Guangdong Natural Science Research Grant(2019A1515010196).; Dear Editor,Lysine residue succinylation is a novel post-translational modification that recently attracted extensive attention.Succinylation is achieved by non-enzymatic processes or by a series of enzymes[like p300,...; 关键词：MITOCHONDRIA SUCCINYLATION PHOSPHORYLATION GLUTAMINASE

The effect of rehabilitation exercise on the expression of glutaminase and cardiopulmonary remodeling in pulmonary hypertension被引量：1: 《Medicine in Novel Technology and Devices》2022年第3期134-143,共10页Shang Wang Ping Yuan Yuan-Yuan Sun Yi Yan Yu-Xia Huang Xiao-Yi Hu Lan Wang Kuan Cheng Rong Jiang; The work was supported by the Program of National Natural Science Foundation of China(81,700,045,82,000,059);the Three-year Action Plan to Promote Clinical Skills and Clinical Innovation in Municipal Hospitals(SHDC2020CR4021);the Program of Shanghai Pulmonary Hospital(FKLY20005).; Pulmonary hypertension(PH)is featured by pulmonary vascular and cardiac remodeling.Rehabilitation exercise can improve patients’quality of life.We previously pinpointed a potential glutamine metabolism dysfunction in...; 关键词：Pulmonary hypertension Pulmonary vascular remodeling Cardiac remodeling GLUTAMINASE

Combination of microwave heating and transglutaminase cross-linking enhances the stability of limonene emulsion carried by whey protein isolate被引量：2: 《Food Bioscience》2022年第3期707-715,共9页Akhunzada Bilawal Xindi Wang Kwang-Chol Oh Abdul Qayum Munkh-Amgalan Gantumur Zhanmei Jiang Juncai Hou; supported by project for the Natural Science Foundation of China(No.32172164);Natural Key Science Foundation of Heilongjiang Province of China(No.ZD2021C007).; In this study,we examined the effect of transglutaminase(TG)cross-linking time(0 h,2 h,4 h,8 h,and 12 h)on the stability of limonene emulsion loaded by microwave-heated WPI(MWPI).Size exclusion chromatography results ...; 关键词：Microwave Whey protein isolates D-LIMONENE EMULSION Stability

Governing glutaminolysis by regulation of glutaminase succinylation: 《Protein & Cell》2022年第3期163-166,共4页Qingxia Ma Hongfei Jiang Leina Ma Ying Meng Dong Guo Yingying Tong Zhimin Lu; This study was supported by grants from Ministry of Science and Technology of the People's Republic of China(2020YFA0803300,Z.L.);the National Natural Science Foundation of China(82188102,82030074,Z.L.;81902423,D.G.);the Zhejiang University Research Fund(188020*194221901/029,Z.L.);the Leading Innovative and Entrepreneur Team Introduction Program of Zhejiang(2019R01001,Z.L.);the Scientific Research Project of Beijing Municipal Education Commission(KM202110025002,Y.T.).Z.L.is the Kuancheng Wang Distinguished Chair.; Of the 20 ribosomally coded amino acid residues,lysine(K)can be frequently and uniquely modified by many types of posttranslational acylation,including acetylation,succinylation,crotonylation,propionylation,butyrylati...; 关键词：uniquely RESIDUES CRITICAL

Curcumin Synergizes with Cisplatin to Inhibit Colon Cancer through Targeting the MicroRNA-137-Glutaminase Axis被引量：7: 《Current Medical Science》2022年第1期108-117,共10页Wen-hui FAN Feng-chun WANG Zhi JIN Lin ZHU Jian-xin ZHANG; Objective:Colorectal cancer(CRC)is one of the most lethal and prevalent malignancies world-wide.Currently,surgery,radiotherapy and chemotherapy are clinically applied as common approaches for CRC patients.Cisplatin is...; 关键词：glutamine metabolism microRNA-137 CURCUMIN cisplatin resistant glutamina

A facile and sensitive method of quantifying glutaminase binding to its ninhibitor CB-839 in tissues被引量：1: 《Journal of Genetics and Genomics》2020年第7期389-395,共7页Yicheng Chen Yiqing Zhao David L.Bajor Zhenghe Wang J.Eva Selfridge; the Case Comprehensive Cancer Center's K12 award(5K12CA076917-22);the Clinical and Translational Science Collaborative TL1 training grant(1TL1TRO02549-01);NIH grants RO1CA196643,UH2CA223670,P5OCA150964,and P30 CA043703;a Stand Up to Cancer Colorectal Cancer Dream Team Translational Research Grant(SU2C-AACR-DT22-17).Stand Up to Cancer is a program of the Entertainment Industry Foundation.; Many cancer types reprogram their metabolism to become addicted to glutamine.One of the critical enzymes in the utilization of glutamine in these cells is glutaminase.CB-839(telaglenastat)is a drug that targets glutam...; 关键词：GLUTAMINASE Method CANCER

Glutaminase inhibition in renal cell carcinoma therapy被引量：2: 《Cancer Drug Resistance》2019年第2期356-364,共9页Aleksandra M.Raczka Paul A.Reynolds; This work was supported by the Melville Trust for Care and Cure of Cancer.; Receptor tyrosine kinase inhibitors have been a standard first-line therapy for renal cell carcinoma(RCC)for over a decade.Although they stabilize the disease,they are unable to remove all tumor cells,leading to relap...; 关键词：Glutamine addiction renal cell carcinoma combination therapy METABOLISM

GLUTAMINASE