supported by the Open Research Fund Program of Anhui Province Key Laboratory of Rice Genetics and Breeding(SDKF-2023-02);the Postdoctoral Research Program of Anhui Province(2022B603);the Key Research and Development Projects in Anhui Province(2023n06020035);the National Natural Science Foundation of China(32230017,U19A2021,and 32321001);the Natural Science Foundation of Anhui province(2408085MC083);the Global Select Project(DJK-LX-2022007)of the Institute of Health and Medicine;the Hefei Comprehensive National Science Center,the Fundamental Research Funds for the Central Universities(WK9100000047);the Anhui Academy of Agricultural Sciences Young Talent Program(QNYC-201902).
Histone H2B ubiquitination(H2Bub)is positively linked to transcriptional activation,but the genetic programs affected by H2Bub to enhance drought tolerance remain largely unknown.Here,we show that OsbZIP27 interacts d...
supported by the grants from the National Natural Science Foundation of China(No.32100611);the Hubei Key Laboratory of Edible Wild Plants Conservation&Utilization(No.EWPL202004).
Autophagy,an efficient and effective approach to clear rapidly damaged organelles,macromolecules,and other harmful cellular components,enables the recycling of nutrient materials and supply of nutrients to maintain ce...
supported by the Major Program of Guangdong Basic and Applied Basic Research(2019B030302006);the National Natural Science Foundation of China(31921004,31871533,and 31760300);the Laboratory of Lingnan Modern Agriculture Project(NT2021002);the Guangdong Basic and Applied Basic Research Foundation(2019A1515010230).
Plant height is an important agronomic trait for lodging resistance and yield.Here,we report a new plantheight-related gene,OsUBR7 in rice(Oryza sativa L.);knockout of OsUBR7 caused fewer cells in internodes,resulting...
the National Key R&D Program of China(2016YFA0501803 and 2017YFA0504504);the National Natural Science Foundation of China(31570766 and U1632130);the Shanghai Municipal Education Commission-Gaofeng Clinical Medicine Grant Support(2017YZ004);the SHIPM-sigma fund(BJ1-7009-18-1303 and JY201805)from Shanghai Institute of Precision Medicine,Ninth People's Hospital,Shanghai Jiao Tong University School of Medicine,and Chinese Academy of Sciences Facility-based Open Research Program.
Dear Editor,Histone marks deposited by post-translational modifications(PTMs)frequently occur in interrelated combinational patterns to create a complex and precise control on the chromatin structure and function.1 On...
Histone H2B monoubiquitination (H2Bub1) plays important roles in several physiological and developmental processes, but its roles in the regulation of plant stress responses remain elusive. Here, we report that H2Bub1...
From mammals to plants, the Polycomb Group (PcG) machinery plays a crucial role in maintaining the repres- sion of genes that are not required in a specific differentiation status. However, the mechanism by which Pe...
Supported by The Ministry of Science and Technology of China,No.2011CB966200 and 2013CB911000;the National Natural Science Foundation of China,No.30970950,81071362,and 31171319;the Program for Changjiang Scholars and Innovative Research Team in University of Ministry of Education of China,the Department of Science and Technology of Sichuan Province,No.2011SZ0002 and 2012JQ0005;the Bureau of Science and Technology of Chengdu,No.11PPYB072SF
AIM:To investigate H2B monoubiquitination(uH2B)and H3K4 di-and tri-methylation(H3K4-2me,H3K4-3me)levels and their clinical significance in gastric cancer(GC).METHODS:Immunohistochemistry(IGC)was used to detect the dif...
Dear Editor, Histone H2B lysine 120 monoubiquitination (H2B- K120ub) is a key histone modification that plays critical roles in gene transcriptional regulation and higher order chromatin organization in many species ...
supported by grants from China MOST 863 project(L.M.);Hebei Province Key Laboratory Program(L.M.);National Science Foundation of China(Y.C.).
Histone ubiquitination plays a critical role in the regulation of transcription,and histone H2B monoubiquitination(H2Bub1)is mainly associated with transcriptional activation.Recent studies in yeast,humans,and Arabido...
AIM To study the membrane trafficking modulation of ROMK1 channel by ubiquitination. METHODS we immunoprecipitated protein with ROMK antibody from rat renal cortex and outer medulla, and apply western blot with ubiqui...