云南高校图书馆联盟文献共享服务平台- PEROXIREDOXINS

PEROXIREDOXINS: 作品数：17被引量：98H指数：5; 导出分析报告; 相关领域：医药卫生生物学更多>>; 相关作者：王世鄂史河秀姚林张志敏孟春燕更多>>; 相关机构：广西医科大学重庆医科大学华中科技大学福建医科大学更多>>; 相关期刊：《毒理学杂志》《中国医药导报》《Journal of Hainan Medical University》《生命科学研究》更多>>; 相关基金：国家自然科学基金福建医科大学科学研究发展基金河北省科技支撑计划项目山东省博士后创新项目更多>>

Peroxiredoxins家族在H_(2)O_(2)诱导人颗粒细胞凋亡过程中的表达: 《华中科技大学学报（医学版）》2023年第1期68-72,共5页沈薇朱燕罗爱月; 国家自然科学基金资助项目(No.81701438)。; 目的探讨Peroxiredoxins(Prdxs)家族在H_(2)O_(2)诱导人颗粒细胞凋亡过程中的作用。方法选取在华中科技大学同济医学院附属同济医院接受体外受精-胚胎移植技术(in vitro fertilization embryo transfer technology,IVF-ET)的年轻患者的...; 关键词：PEROXIREDOXINS 颗粒细胞凋亡过氧化氢

Celastrol induces ferroptosis in activated HSCs to ameliorate hepatic fibrosis via targeting peroxiredoxins and HO-1被引量：43: 《Acta Pharmaceutica Sinica B》2022年第5期2300-2314,共15页Piao Luo Dandan Liu Qian Zhang Fan Yang Yin-Kwan Wong Fei Xia Junzhe Zhang Jiayun Chen Ya Tian Chuanbin Yang Lingyun Dai Han-Ming Shen Jigang Wang; supported by the National Key Research and Development Program of China (2020YFA0908000);the Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine (ZYYCXTD-C-202002,China);the National Natural Science Foundation of China(81903588,81803456,82074098 and 81841001,China);the Fundamental Research Funds for the Central Public Welfare Research Institutes (ZXKT18003 and ZZ15-YQ-063,China)。; Ferroptosis is a form of regulated cell death, characterized by excessive membrane lipid peroxidation in an iron-and ROS-dependent manner. Celastrol, a natural bioactive triterpenoid extracted from Tripterygium wilfor...; 关键词：CELASTROL Ferroptosis PEROXIREDOXIN HO-1 Hepatic fibrosis ABPP ANTI-OXIDANT Reactive oxygen species

Parvifoline AA靶向Peroxiredoxins Ⅰ/Ⅱ激活NK细胞介导的肝脏肿瘤免疫: 《科学新闻》2020年第2期113-113,共1页朱惠芳王彬 Lingmei Kong Tao An Gentao Li Hongyu Zhou Liang Gong Zhangxun Zhao Yaxiao Gong Handong Sun 普诺·白玛丹增李艳; 国家自然科学基金;昆明植物所特色研究所服务项目;云南省高端科技人才项目的支持。; 文章简介诸多临床研究已证实肿瘤免疫治疗可改善肿瘤患者的预后,显著延长患者的生存期。自然杀伤细胞(NK)是重要的免疫细胞类群,其表面的活化型受体NKG2D与肿瘤细胞表面对应配体的相互作用对于NK细胞执行早期肿瘤免疫监视非常重要。; 关键词：肿瘤免疫治疗肝脏肿瘤免疫细胞 NK细胞肿瘤免疫监视 NKG2D 活化型肿瘤患者

Relationship between peroxiredoxins protein family levels and osteoporosis in postmenopausal woman: 《Journal of Hainan Medical University》2019年第11期38-43,共6页Hong Fang Lin Lu; Objective:To observe the expression levels of the main molecules of peroxiredoxins (Prdxs) protein family (Prdx1, Prdx2, Prdx4 and Prdx6) in women with postmenopausal osteoporosis (PMOP), and to analyze their clinical...; 关键词：POSTMENOPAUSAL woman OSTEOPOROSIS PEROXIREDOXINS Plasma lipid LEVELS NEUTROPHILS LYMPHOCYTES ratio

2-Cys Peroxiredoxins Participate in the Oxidation of Chloroplast Enzymes in the Dark: 《Molecular Plant》2018年第11期1377-1388,共12页Valle Ojeda Juan Manuel Perez-Ruiz Francisco Javier Cejudo; Most redox-regulated chloroplast enzymes are reduced during the day and oxidized during the night.While the reduction mechanism of light-dependent enzymes is well known,the mechanism mediating their oxidation in the d...; 关键词：CHLOROPLAST enzyme OXIDATION PEROXIREDOXIN THIOREDOXIN hydrogen peroxide DARKNESS

Peroxiredoxins在肿瘤中的研究进展被引量：2: 《中国医药导报》2017年第25期38-41,57,共5页曾伟肖涛蔡安烈; 湖南省自然科学基金项目(2017JJ4068);湖南省医药卫生科研计划项目(B2016172); Peroxiredoxins(Prdx)是细胞内存在一类抗氧化酶,它们能催化氧化还原反应而维持细胞内过氧化氢水平的平衡,并作为氧化还原信号通路中的一个重要调节因子,这对于细胞信号转导和代谢十分重要。Prdx家族在肿瘤中发挥着不同的作用。由于肿...; 关键词：PEROXIREDOXINS 肿瘤活性氧簇氧化还原治疗

Expression of Peroxiredoxins and Pulmonary Surfactant Protein A Induced by Silica in Rat Lung Tissue被引量：7: 《Biomedical and Environmental Sciences》2016年第8期584-588,共5页LIU Nan XUE Ling GUAN Yi LI Qing Zhao CAO Fu Yuan PANG Shu Lan GUAN Wei Jun; supported by the Applied Basic Research Program at Hebei Province in China(Grant No.11966120D); Silicosis is one of the most serious occupational diseases in China and dates back to centuries ago. In this study, we successfully established a rat model of silicosis by intratracheal silica injection for 28 days an...; 关键词：Expression of Peroxiredoxins and Pulmonary Surfactant Protein A Induced by Silica in Rat Lung Tissue SP Figure

Redox regulation of mammalian sperm capacitation被引量：9: 《Asian Journal of Andrology》2015年第4期583-590,共8页Cristian O'Flaherty; Capacitation is a series of morphological and metabolic changes necessary for the spermatozoon to achieve fertilizing ability. One of the earlier happenings during mammalian sperm capacitation is the production of rea...; 关键词：DEHYDROGENASES OXIDASES PEROXIREDOXINS reactive oxygen species spermatozoa THIOLS THIOREDOXINS

Selective silencing of 2Cys and type-ⅡB Peroxiredoxins discloses their roles in cell redox state and stress signaling被引量：1: 《Journal of Integrative Plant Biology》2015年第6期591-601,共11页Patrícia Vidigal Ana Montserrat Martin-Hernandez Cèlia Guiu-Aragonés Sara Amncio Luísa Carvalho; funded by Fundao para a Ciência e Tecnologia (FCT): CBAA (Pest OE/AGR/UI0240/2011);the postdoc grants SFRH/BPD/43898/2008 to PV;SFRH/BPD/85767/ 2012 to LC; Peroxiredoxins （Prx） catalyse the reduction of hydrogen peroxide （H2O2） and, in association with catalases and other peroxidases, may participate in signal transduction by regulating intercel ular H2O2 concentrati...; 关键词：2-Cys Peroxiredoxin abscisic acid ASCORBATE heat stress hydrogen peroxide PEROXISOME type-Ⅱ Peroxiredoxin B

槲皮素对矽尘致肺纤维化的干预作用及对Prxs蛋白的表达影响研究被引量：4: 《毒理学杂志》2014年第6期443-445,450,共4页张志敏张艳淑关维俊孟春燕姚林; 河北省卫生厅项目(20110162);河北省科技支撑项目(02976194D); 目的探讨槲皮素对矽尘致肺纤维化的干预作用以及对Prxs蛋白的表达影响,为矽肺的临床治疗提供新的思路。方法选取24只雄性健康成年SPF级SD大鼠,随机分为3组(对照组、染尘组和干预组)。对照组大鼠经气管注入无菌生理盐水1 ml,染尘组大鼠...; 关键词：矽肺槲皮素 Peroxiredoxins(Prxs) 肺纤维化氧化损伤

PEROXIREDOXINS