Tyrosol is a natural phenolic compound with antioxidant,anti-inflammatory and other biological activities,serving as an important precursor of high-value products such as hydroxytyrosol and salidroside.Therefore,the g...
supported by the National Natural Science Foundation of China(Grant Nos.:82274207,81973569,22034005);the Xinglin Scholar Research Promotion Project of Chengdu University of Traditional Chinese Medicine,China(Grant No.:XKTD2022013);the Sichuan Provincial Natural Science Foundation,China(Grant No.:24NSFSC1748).
Microneurovascular units(mNVUs),comprising neurons,micro-glia,and blood-brain barrier(BBB)endothelial cells,are pivotal to the central nervous system and are associated with cerebral hypoxia and brain injuries.Cerebra...
supported by the grants from the National Natural Science Foundation of China(No.82300745 to Y.L.);the China Postdoctoral Science Foundation(No.2023M730442 to Y.L.);the Chongqing Postdoctoral Science Foundation(No.CSTB2023NSCQ-BHX0103 to Y.L.).
Acute rejection is an important factor affecting the survival of recipients after liver transplantation.Salidroside has various properties,including anti-inflammatory,antioxidant,and hepatoprotective properties.This s...
supported by Shandong Provincial Natural Science Foundation,China(No.ZR2020MH336);Weifang Science and Technology Development Plan Project(NO.2022GX015,NO.2022GX010).
Objective This study aimed to clarify the intervention effect of salidroside(SAL)on lung injury caused by PM_(2.5) in mice and illuminate the function of SIRT1-PGC-1ɑaxis.Methods Specific pathogen-free(SPF)grade male...
Objective: To obtain detailed understanding on the gene regulation of natural compounds in altering prognosis of head and neck squamous cell carcinomas(HNSC). Methods: Gene expression data of HNSC samples and peripher...
This work was supported by the grants from the National Natural Science Foundation of China(No.82160338);the Youth Innovation and Talent Training Project of Shihezi University(No.CXPY202008);the School-level Scientific Research Projects supported by Shihezi University(Nos.ZZZC202196 and ZZZC2022091);the College-level Project of the First Affiliated Hospital of Medical College of Shihezi University(No.QN202127);Corps Science and Technology Plan Project(No.KY000109).
Arsenic is a natural metal found in nature.Excessive intake of arsenic in the human body can lead to acute and chronic arsenic poisoning and even induce various diseases,such as cancers[1].According to statistics,appr...
supported by the grants from the National Natural Science Foundation of China(No.82160338);the Youth Innovation and Talent Training Project of Shihezi University(No.CXPY202008);the School-level Scientific Research Projects supported by Shihezi University(Nos.ZZZC202196 and ZZZC2022091);the Collegelevel Project of the First Affiliated Hospital of Medical College of Shihezi University(No.QN202127).
Sepsis is a systemic inflammatory response syndrome caused by infection that affects millions of people each year and carries a high risk of death.It has become a global public health problem[1].Sepsis mediates mitoch...
supported by the Zhejiang Traditional Chinese Medicine Science and Technology Plan Project(2021ZB027,2023ZL267);Zhejiang Medical and Health Platform Project of China(2019KY002,2019RC092).
Objective: To evaluate the effect of salidroside on oxygen and glucose deprivation(OGD)-treated NT2 cells and its underlying mechanisms of action.Methods: Retinoic acid was used to induce the differentiation of NT2 ce...
Special Science and Technology Research Project of Sichuan Provincial Administration of Traditional Chinese Medicine(2021MS121).
[Objectives]To use poly(lactic-co-glycolic acid)(PLGA)nanoparticles to improve the bioavailability and brain entrance capability of Salidroside(Sal).[Methods]An emulsion solvent evaporation approach was used to create...
supported by The Key-Area Research and Development Program of Guangdong Province(2020B0303070002),China。
Salidroside(8-O-β-D-glucoside of tyrosol),a plant-derived natural product,is used for treatment of hypoxia,fatigue and aging diseases.The availability of salidroside is restricted since it is extracted from3-5 years ...