SCUTELLAREIN

作品数:11被引量:30H指数:4
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相关领域:医药卫生更多>>
相关作者:陈运贞马长生李法琦雷寒周建中更多>>
相关机构:重庆医科大学附属第一医院中日友好医院中山医科大学哈尔滨医科大学更多>>
相关期刊:《International Journal of Ophthalmology(English edition)》《Chinese Medical Journal》《生殖医学杂志》《Chinese Journal of Structural Chemistry》更多>>
相关基金:国家自然科学基金更多>>
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Scutellarein Ameliorated Chondrocyte Inflammation and Osteoarthritis in Rats
《Current Medical Science》2024年第2期355-368,共14页Shao-ze JING Shu-han YANG Yun-kun QU Hai-hu HAO Hua WU 
financially sponsored by the National Natural Science Foundation of China(No.51537004).
Objective:Osteoarthritis(OA)is a degenerative joint disorder characterized by the gradual degradation of joint cartilage and local inflammation.This study aimed to investigate the anti-OA effect of scutellarein(SCU),a...
关键词:SCUTELLAREIN OSTEOARTHRITIS APOPTOSIS mitogen-activated protein kinase(MAPK) nuclear factor kappa-B(NF-κB) 
A Cocktail of Natural Compounds Holds Promise for New Immunotherapeutic Potential in Head and Neck Cancer被引量:2
《Chinese Journal of Integrative Medicine》2024年第1期42-51,共10页Sunil Kumar Asmita Das 
Objective: To obtain detailed understanding on the gene regulation of natural compounds in altering prognosis of head and neck squamous cell carcinomas(HNSC). Methods: Gene expression data of HNSC samples and peripher...
关键词:natural compounds CHEMOPREVENTIVE gene expression head and neck cancer IMMUNOMODULATOR SALIDROSIDE ginsenoside Rd ORIDONIN britanin SCUTELLAREIN 
Scutellarein alleviates the dysfunction of inner blood-retinal-barrier initiated by hyperglycemia-stimulated microglia cells被引量:3
《International Journal of Ophthalmology(English edition)》2020年第10期1538-1545,共8页Han Li Xi-Yu Mei Meng-Na Wang Tian-Yu Zhang Yue Zhang Bin Lu Yu-Chen Sheng 
Supported by the National Key Research and Development Program of China(No.2018YFC1707302);National Natural Science Foundation of China(No.81960748)。
AIM:To investigate the alleviation of scutellarein(SN)against inner blood-retinal-barrier(iBRB)dysfunction in microglia cells stimulated by hyperglycemia and to elucidate the engaged mechanism.METHODS:Microglia BV2 ce...
关键词:SCUTELLAREIN blood-retinal-barrier tight junctions inflammation tumor necrosis factorα 
Geometrical Structures and Activities of Free Radical Scavenging Studies of Baicalein and Scutellarein
《Chinese Journal of Structural Chemistry》2020年第1期57-65,2,共10页QIU Song-Shan JIANG Cui-Cui ZHOU Ru-Jin LI Chun-Hai 
This project was supported by the Natural Science Fundation of Guangdong Province(2018A030307051);Science and Technology Planning Project of Guangdong Province(2017A020225043 and 2012gczx B001)。
In order to study the free radical scavenging capacity and molecular structures of baicalein and scutellarein,the structure-activity relationship of these two molecules was analyzed.The geometric structures of the com...
关键词:density FUNCTIONAL theory BAICALEIN SCUTELLAREIN free RADICAL SCAVENGING 
Antiarthritic Activity of Apigenin, Scutellarein and Pectinolinergenin Glycosides from Clerodendron inerme
《Journal of Agricultural Science and Technology》2011年第3期257-266,共10页S. Somasundaram C. Edwards 
The present study was aimed to investigate the anti-arthritic activity of alcoholic extract ofClerodendron inerme which was shown to inhibit inflammatory process. Arthritis was induced in rats by injecting rats intrad...
关键词:Antiarthritic Clerodendron inerme APIGENIN scutallarin pectinolinergenin. 
Metabolic and pharmacokinetic studies of scutellarin in rat plasma, urine, and feces被引量:11
《Acta Pharmacologica Sinica》2011年第5期655-663,共9页Jian-feng XING Hai-sheng YOU Ya-lin DONG Jun LU Si-ying CHEN Hui-fang ZHU Qian DONG Mao-yi WANG Wei-hua DONG 
Acknowledgements This work was supported by the National Natural Science Foundation of China (No 30973673 and 30973578).
Aim: To study the metabolic and pharmacokinetic profile of scutellarin, an active component from the medical plant Erigeron breviscapus (Vant) Hand-Mazz, and to investigate the mechanisms underlying the low bioavai...
关键词:SCUTELLARIN SCUTELLAREIN metabolism PHARMACOKINETICS excretions gender differences 
Scutellarein inhibits hypoxia- and moderately-high glucose-induced proliferation and VEGF expression in human retinal endothelial cells被引量:6
《Acta Pharmacologica Sinica》2008年第6期707-712,共6页Rong GAO Bang-hao ZHU Shi-bo TANG Jiang-feng WANG Jun REN 
Aim: This study was designed to examine the effect of scutellarein on high glucose- and hypoxia-stimulated proliferation of human retinal endothelial cells (HREC). Methods: HREC were cultured under normal glucose ...
关键词:SCUTELLAREIN human retinal endothelial cells vascular endothelial growth factor HYPOXIA high glucose diabetic retinopathy 
Two new flavonoid diglycosides from Cephalotaxus sinensis被引量:1
《Chinese Chemical Letters》2007年第7期837-839,共3页Wei Li Rong Ji Dai Yu Hong Yu Liang Li Wei Wei Meng Yu Lin Deng 
Two new acetylated flavonoid diglycosides, scutellarein-5-O-[α-L-rhamnopyranosyl-(1 → 4)-β-D-6-O-acetylglucopyranoside](1), apigenin-5-O-[α-L-rhamnopyranosyl-(1→ 2)-β-D-3,6-di-O-acetylglucopyranoside] (2...
关键词:Cephalotaxus sinensis (Rehd et Wile) Li Flavonoid diglycosides Scutellarein-5-O-[α-L-rhamnopyranosyl-(1→ 4)-β-D-6-O-acetylglucopyranoside] Apigenin-5-O-[α-L-rhamnopyranosyl-(1  2)-β-D-3 6-di-O-acetylglucopyranoside] 
Effective component from verbena officinalis L.inhibits proliferation and induces apoptosis of human choriocarcinoma JAR cells被引量:4
《生殖医学杂志》2005年第B10期12-18,共7页徐珊 陈琪 徐昌芬 
Objective:To examine the action of the effective component,4'-methylether-scutellarein,from Verbena officinalis L.(VOL)on the proliferation and apoptosis of human choriocarcinomaJAR cells.Methods:Cell proliferation wa...
关键词:ANTI-CANCER CHORIOCARCINOMA 4’-methylether-scutellarein Verbena officinalis L. APOPTOSIS 
Ventricular remodeling by Scutellarein treatment in spontaneously hypertensive rats被引量:5
《Chinese Medical Journal》2002年第3期375-377,共3页周建中 雷寒 陈运贞 李法琦 马长生 
OBJECTIVE: To observe reversal of ventricular remodeling by the protein kinase C inhibitor Scutellarein in spontaneously hypertensive rats (SHRs). METHODS: Twelve SHRs were randomly divided into two groups. Scutellare...
关键词:FLAVANONES ANIMALS Female FLAVONOIDS Hypertension Male Protective Agents Protein Kinase C Random Allocation RATS Rats  Inbred SHR Ventricular Remodeling 
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