云南高校图书馆联盟文献共享服务平台- PRESYNAPTIC

PRESYNAPTIC: 作品数：30被引量：25H指数：3; 导出分析报告; 相关领域：医药卫生生物学更多>>; 相关机构：苏州大学更多>>; 相关期刊：《Journal of Otology》《Journal of Pharmaceutical Analysis》《神经解剖学杂志》《Open Journal of Anesthesiology》更多>>; 相关基金：国家自然科学基金中国博士后科学基金北京市自然科学基金国家重点基础研究发展计划更多>>

Beginning from the end:the presynaptic terminal as a pathomechanism hub in frontotemporal dementia and amyotrophic lateral sclerosis: 《Neural Regeneration Research》2025年第11期3217-3218,共2页Laura Huggon Emma L.Clayton; funded by a senior research fellowship from Alzheimer’s Research UK (ARUK-SRF2022A-005);funded by a PhD studentship from Alzheimer’s Society (571);supported by the UK Dementia Research Institute through UK DRI Ltd.;principally funded by the UK Medical Research Council; Frontotemporal dementia and amyotrophic lateral sclerosis:Frontotemporal dementia(F T D)and amyo t rophic lateral sclerosis(ALS)are neurodegenerative diseases with significant overlapping attributes.While these neurod...; 关键词：DISEASES amyotrophic SCLEROSIS

Recent progress in the applications of presynaptic dopaminergic positron emission tomography imaging in parkinsonism: 《Neural Regeneration Research》2025年第1期93-106,共14页Yujie Yang Xinyi Li Jiaying Lu Jingjie Ge Mingjia Chen Ruixin Yao Mei Tian Jian Wang Fengtao Liu Chuantao Zuo; supported by the Research Project of the Shanghai Health Commission,No.2020YJZX0111(to CZ);the National Natural Science Foundation of China,Nos.82021002(to CZ),82272039(to CZ),82171252(to FL);a grant from the National Health Commission of People’s Republic of China(PRC),No.Pro20211231084249000238(to JW);Medical Innovation Research Project of Shanghai Science and Technology Commission,No.21Y11903300(to JG).; Nowadays,presynaptic dopaminergic positron emission tomography,which assesses deficiencies in dopamine synthesis,storage,and transport,is widely utilized for early diagnosis and differential diagnosis of parkinsonism....; 关键词：aromatic amino acid decarboxylase brain imaging dopamine transporter Parkinson’s disease PARKINSONISM positron emission tomography presynaptic dopaminergic function vesicle monoamine transporter type 2

Presynaptic endoplasmic reticulum architecture and hereditary spastic paraplegia: 《Neural Regeneration Research》2024年第3期485-486,共2页Juan JoséPérez-Moreno; supported by Juan de la Cierva Incorporación grant(IJC2019-038819-I);the Spanish State Research Agency(MCIN/AEI/10.13039/501100011033)(to JJPM).; Hereditary spastic paraplegia(HSP)is a clinically and genetically heterogeneous neurodegenerative disorder,characterized primarily by progressive spasticity and weakness in the lower limbs.Pat ients can also experienc...; 关键词：reticulum endoplasmic

Selective deletion of zinc transporter 3 in amacrine cells promotes retinal ganglion cell survival and optic nerve regeneration after injury被引量：2: 《Neural Regeneration Research》2023年第12期2773-2780,共8页Zhe Liu Jingfei Xue Canying Liu Jiahui Tang Siting Wu Jicheng Lin Jiaxu Han Qi Zhang Caiqing Wu Haishun Huang Ling Zhao Yehong Zhuo Yiqing Li; the National Key R&D Project of China,No.2020YFA0112701(to YZ);the National Natural Science Foundation of China,Nos.82171057(to YZ),81870657(to YL);Science and Technology Program of Guangzhou of China,No.202206080005(to YZ);the Natural Science Foundation of Guangdong Province of China,No.2022A1515012168(to YL)。; Vision depends on accurate signal conduction from the retina to the brain through the optic nerve,an important part of the central nervous system that consists of bundles of axons originating from retinal ganglion cel...; 关键词：axonal regeneration conditional knockout NEUROTRANSMITTER optic nerve injury presynaptic neuron retinal network synaptic connection synaptic vesicles visual acuity zinc transporter 3

Impaired dynamic interaction of axonal endoplasmic reticulum and ribosomes contributes to defective stimulus-response in spinal muscular atrophy: 《Translational Neurodegeneration》2022年第1期474-495,共22页Chunchu Deng Sebastian Reinhard Luisa Hennlein Janna Eilts Stefan Sachs Sören Doose Sibylle Jablonka Markus Sauer Mehri Moradi Michael Sendtner; Open Access funding enabled and organized by Projekt DEAL.Chunchu Deng was funded by PicoQuant and the Deutsche Forschungsgemeinschaft(DFG)Grant Se697/7-1,Project Number 405988308,DFG Grant JA1823/3-1 for SJ and Cure SMA for SJ,Grant JAB1920.PicoQuant did not influence project design,conduction of experiments or data analyses.; Background:Axonal degeneration and defects in neuromuscular neurotransmission represent a pathological hall-mark in spinal muscular atrophy(SMA)and other forms of motoneuron disease.These pathological changes do not o...; 关键词：Spinal muscular atrophy Presynaptic ER dynamics Dynamics of ribosomal assembly BDNF stimulation

主旨报告: 《神经药理学报》2019年第2期1-7,共7页; PL-1 Presynaptic Endosomal Cathepsin D Regulates the Biogenesis of GABAergic Synaptic Vesicles DUAN Shu-min Zhejiang University School of Medicine,Hangzhou,310058,China Dr. Shumin Duan is a professor at Zhejiang Unive...; 关键词：PRESYNAPTIC Endosomal CATHEPSIN BIOGENESIS

Whole-brain patterns of the presynaptic inputs and axonal projections of BDNF neurons in the paraventricular nucleus被引量：2: 《Journal of Genetics and Genomics》2019年第1期31-40,共10页Fang Luo Yuling Mu Cuicui Gao Yan Xiao Qian Zhou Yiqing Yang Xinyan Ni Wei L.Shen Jiajun Yang; funded by the Pudong New Area Science and Technology Development Fund,China (J. Yang,#PKJ2014-Y08);Shanghai University of Medicine & Health Sciences Seed Foundation Project,China (J. Yang,#SPF-18-20-14-006);ational Natural Science Foundation of China (W. Shen,#31771169 and #91857104);Thousand Young Talents Program of China (W. Shen);ShanghaiTech University start-up fund (W. Shen); Brain-derived neurotrophic factor (BDNF) plays a crucial role in human obesity. Yet, the neural circuitry supporting the BDNF-mediated control of energy homeostasis remains largely undefined. To map key regions that m...; 关键词：BDNF Transsynaptic TRACING Obesity Feeding THERMOGENESIS

Presynaptic mechanisms at prefrontal synapses involved in persistent pain: 《Neuroimmunology and Neuroinflammation》2018年第9期40-47,共8页Hiroki Toyoda; The cumulative evidence from animal and human studies revealed that the anterior cingulate cortex (ACC) plays essential roles in pain sensation and persistent pain. It has been evident in the ACC synapses of animals t...; 关键词：PRESYNAPTIC mechanism chronic PAIN ANTERIOR CINGULATE CORTEX

Role of presynaptic calcium stores for neural network dysfunction in Alzheimer＇s disease: 《Neural Regeneration Research》2018年第6期977-978,共2页Chommanad Lerdkrai Olga Garaschuk; supported by the Volkswagen Stiftung(grant No.90233)to OG; Alzheimer’s disease（AD）is the most common form of dementia representing a major problem for public health.In 2017 there were an estimated 50 million patients worldwide and this number is expected to almost double e...; 关键词：In Role of presynaptic calcium stores for neural network dysfunction in Alzheimer’s disease AD

TDP-43 overexpression impairs presynaptic integrity: 《Neural Regeneration Research》2016年第12期1910-1911,共2页Lanier Heyburn Charbel E-H.Moussa; supported by Georgetown University funding to Moussa CE.Moussa CE,M.D.,Ph.D.,is listed as an inventoron a pending U.S.patent application to use tyrosine kinase inhibitors as a treatment for neurodegenerative diseases; The pathological mechanisms associated with the trans-activating response DNA/RNA binding protein（TDP）-43 remain largely enigmatic.Accumulation,insolubility and post-translational modification of nuclear and cytopla...; 关键词：TDP-43 overexpression impairs presynaptic integrity CYCLE TCA MND

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