Diabetic wound healing has become a serious healthcare challenge.The high-glucose environment leads to persistent bacterial infection and mitochondrial dysfunction,resulting in chronic inflammation,abnormal vascular f...
supported by the National Natural Science Foundation of China(Grant No.52272276,52073103,52203164);the Key-Area Research and Development Program of Guangdong Province(Grant No.2020B090924004);the funds for Zhongshan Innovation Project of high-end Scientific Research Institutions(Grant No.2020AG020);the Fundamental Research Funds for the Central Universities(No.2022ZYGXZR105);Guangdong Basic and Applied Basic Research Foundation(Grant No.2021A1515010905).
Bacterial infection,excessive inflammation and damaging blood vessels network are the major factors to delay the healing of diabetic ulcer.At present,most of wound repair materials are passive and can’t response to t...
This research was supported by Nano⋅Material Technology Development Program through the National Research Foundation of Korea(NRF)funded by Ministry of Science and ICT(NRF-2021M3H4A1A03048658,NRF-2021M3H4A1A04092883).
Implantable biomedical devices require an anti-biofouling,mechanically robust,low friction surface for a prolonged lifespan and improved performance.However,there exist no methods that could provide uniform and effect...
grants from Sichuan Key Research and Development Program of China(22ZDYF2034);National Natural Science Foundation of China(grant no.82072071,82072073);Key-Area Research and Development Program of Guang Dong Province(2019B010941002);Shenzhen Funds of the Central Government to Guide Local Scientific and Technological Development(2021SZVUP123);Sichuan Science and Technology Program(2020YFS0170);Fundamental Research Funds for the Central Universities(2682020ZT79);Guangdong Basic and Applied Basic Research Foundation(2021B1515120019);Research and Develop Program,West China Hospital of Stomatology Sichuan University(RD-03-202012,RD-03-202101).
Regenerating periodontal bone tissues in the aggravated inflammatory periodontal microenvironment under diabetic conditions is a great challenge.Here,a polydopamine-mediated graphene oxide(PGO)and hydroxyapatite nanop...
the National Natural Science Foundation of China(Grant No.82160430,81972120 and 82160188);the Natural Science Foundation of Guangxi(Grant No.2020GXNSFAA159134);the Guangxi Science and Technology Base and Talent Special Project(Grant No.GuikeAD21075002 and GuikeAD19254003).
Excessive cell-free DNA(cfDNA)released by damaged or apoptotic cells can cause inflammation,impacting the progression of rheumatoid arthritis(RA).cfDNA scavengers,such as cationic nanoparticles(NPs),have been demonstr...
the National Natural Science Foundation of China(No.82002313,No.82072444);China Postdoctoral Science Foundation(No.2021M701333);Department of Science and Technology of Hubei Province(No.2021CFB425,No.2020BCB004);Hubei Province Key Laboratory of Oral and Maxillofacial Development and Regeneration(2021kqhm007).
Major traumatic tissue defects are common clinical problems often complicated by infection and local vascular dysfunction, processes which hinder the healing process. Although local application of growth factors or st...
supported by the National Natural Science Foundation of China(No.51773130,52073216 and 51903172);National Science Foundation of Zhejiang province(LY20B040004).
Bacterial infection is a vital factor to delay the wound healing process.The antibiotics abuse leads to drug resistance of some pathogenic bacteria.Non-antibiotic-dependent multifunctional biomaterials with accelerate...
Bone tumors occur in bone or its accessory tissues.Benign bone tumors are easy to cure and have good prognosis,while malignant bone tumors develop rapidly and have poor and high mortality.So far,there is no satisfacto...
This research was supported by the Basic Science Research Program(2020R1A2C3014070);the Korea Medical Device Development Fund grant(2020M3E5D8105732);Bio&Medical Technology Development Program(2021M3E5E7021473);the Engineering Research Center(ERC)Program(NRF-2017R1A5A1014708)of the National Research Foundation(NRF)funded by the Ministry of Science and ICT,Korea.
Self-propelling micro-and nano-motors(MNMs)have been extensively investigated as an emerging oral drug delivery carrier for gastrointestinal(GI)tract diseases.However,the propulsion of current MNMs reported so far is ...
This work was financially supported by the National Natural Science Foundation of China(81700086);Shanghai Municipal Commission of Health and Family Planning Foundation(20134087).
Stem cell-derived exosomes(SC-EXO)was an emerging therapeutic agent in regenerative medicine.Intratunical injection of SC-EXO is considered as a prospective approach for erectile dysfunction(ED)treatment.However,high ...