supported by the National Natural Science Foundation of China(No.82100700 to F.Y.);the China Postdoctoral Science Foundation(No.2020M670101ZX to F.Y.);the Fundamental Scientific Research Project from the Educational Department of Liaoning Province,China(No.LJKMZ20221191 to F.Y.);the 345 Talent Project of Shengjing Hospital of China Medical University(No.52-30B to F.Y.).
Digestive-system cancers represent major threats to human health;however,the mechanisms underlying tumorigenesis and radiochemotherapy resistance have remained elusive.Therefore,an urgent need exists for identifying k...
This study aims to evaluate the effect of serum concentration, synchronization time, and confluence degree on the synchronisation efficiency of goat fibroblast cycle. The results indicated that there was no difference...
supported by National Key R&D Program of China(Grant Number.2020YFA0908800);National Natural Science Foundation of China(Grant Number.81871376,32171365,82027803,81971623 and 82202151);Strategic Priority Research Program of the Chinese Academy of Sciences(Grant Number.XDB0480000);China Postdoctoral Science Foundation(Grant Number.2021M700121);Shenzhen Science and Technology Innovation Committee(Grant Number.JCYJ20190812171820731);Shenzhen Institute of Synthetic Biology Scientific Research Program(Grant Number.JCHZ20210002).
Gene delivery is the process by which foreign DNA is transferred to host cells,released from intracellular vesicles,and transported to the nuclei for transcription.This process is frequently inefficient and difficult ...
This experiment was supported by the National Natural Science Foundation of China(No.81872972).
Objective:The morbidity of malignant melanoma keeps increasing annually.It has high risks of metastasis,drug resistance,and poor prognosis in clinics.Moreover,the available medicines used commonly,such as dacarbazine,...
This work was supported by grants from the Shanghai Natural Science Foundation(20ZR1403800)to Y.F.The project was also supported by the Natural Science Foundation of China(31930044,31725012);the Foundation of Shanghai Municipal Education Commission(2019-01-07-00-07-E00062);the Collaborative Innovation Program of Shanghai Municipal Health Commission(2020CXJQ01);the Shanghai Municipal Science and Technology Major Project(No.2018SHZDZX01).
Dear Editor,GABAergic interneurons contribute to cortical function by regulating the balance of activity.Malfunction of inhibitory interneurons has been associated with neuropsychiatric disorders(Hashimoto et al.2003;...
The lab of ED is supported by:The Swedish Research Council(contract No.2013-9279),the Knut and Alice Wallenberg Foundation(contract No.2015-0030),the European Research Council(project EC-ERC-VEPC,contract 74292),Associazione Italiana per la Ricerca sul Cancro(AIRC IG 23223),AIRC 5x1000 call"Metastatic disease:the key unmet need in oncology"to the MYNERVA Project(MYeloid NEoplasms Research Venture AIRC 21267),Telethon(New insight on the pathogenesis of hereditary Cerebral Cavernous Malformation,contract GGP19202);AIFA(a multicellular randomized clinical trial on propranolol in familial Cerebral Cavernous Malformation,contract AIFA-2016-02364593).Be Brave for Life Foundation Micro Grant 2019.
The programmed cell death 10(PDCD10)gene was originally identified as an apoptosis-related gene,although it is now usually known as CCM3,as the third causative gene of cerebral cavernous malformation(CCM).CCM is a neu...
National Natural Science Foundation of China (91639106 to H-bX, 81660041 to L-bD);National Basic Research Program of China (2013CB531103 to H-bX and L-bD);Jiangxi Province Science Foundation for Youths (20122BA B215020 to H-wC).
Cancer cells always require more nutrients, energy, and biosynthetic activity to sustain their rapid proliferation than normal cells. Previous studies have shown the impact of THZ1, a covalerrt inhibitor of ryHirwjepe...
National Natural Science Foundation of China (No. 81670265);Hunan Provincial Natural Science Foundation (No. 2017JJ2227).
Cardiomyocytes, also known as myocardial fibers, are the muscle cells which form the heart tissue. Previous studies have indicated that fetal mammalian cardiomyocytes maintain the regeneration capacity, which promotes...
Study of network dynamics is very active area in biological and social sciences. However, the relationship between the network structure and the attractors of the dynamics has not been fully understood yet. In this st...