The authors extend their appreciation to the Distinguished Scientist Fellowship program at King Saud University,Riyadh,Saudi Arabia,for funding this work through Research Supporting Project Number RSP2024R131.
Background:Besides seizures,a myriad of overlapping neuropsychiatric and cognitive comorbidities occur in patients with epilepsy,which further debilitates their quality of life.This study provides an in-depth characte...
The authors extended their appreciation to Distinguished Scientist Fellowship program at King Saud University,Riyadh,Saudi Arabia,for funding this work through research supporting project number(RSP2024R131).
Background:Scientific evidence to guide clinicians on the use of different antiseizure drugs in combination therapy is either very limited or lacking.In this study,the impact of lacosamide and perampanel alone and in ...
Objective:To assess the effect of sericin against pentylenetetrazole(PTZ)kindling epilepsy and its associated comorbidities.Methods:Epilepsy was induced with PTZ at the dose of 30 mg/kg i.p.on alternative days for 25 ...
This book presents the historical evolution of book printing in China,from knotting records to modern engraving.It is divided into two parts:the first part mainly discusses the development of paper-making and engravin...
Background:Pentylenetetrazole kindling has long been used for the screening of investigational antiseizure drugs.The presence of lamotrigine,at a very low dose,does not hamper kindling in mice;rather it modifies this ...
Background:Epilepsy is a chronic and severe neurological disorder.Phosphatase and tensin homolog deleted on chromosome ten(PTEN)-deficient mice exhibit learning and memory deficits and spontaneous epilepsy.The aim of ...
Emotional disturbances such as anxiety, fear, depression and aggression are often experienced by patients with temporal lobe epilepsy. These psychiatric symptoms may occur during or just after (postictal) a seizure;ho...
supported by grants from National Natural Science Foundation of China(No.81241129/H0913);Guizhou Province Governor Special Funds(No.1065-09)and Guizhou High-level Personnel Scientific Funds(No.TZJF-2010-054)
Synaptic vesicle protein 2A(SV2A) involvement has been reported in the animal models of epilepsy and in human intractable epilepsy. The difference between pharmacosensitive epilepsy and pharmacoresistant epilepsy re...
This paper deals with certain psychic automatisms that appear suddenly in the consciousness of the subject in a passive or automatic way and that usually are diagnosed as psychiatric symptoms or manifestations of an e...
The main objective of the study was to determine the effect of gestation and postgestation periods on development and course of seizure activity. The data obtained in the study showed that i) there is a reduction of b...