EPITHELIA

作品数：56被引量：81H指数：5
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相关机构：河北科技师范学院襄樊市中心医院山东中医药大学附属眼科医院第四军医大学更多>>
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Regulatory factors of Nrf2 in age-related macular degeneration pathogenesis
《International Journal of Ophthalmology(English edition)》2024年第7期1344-1362,共19页Zi-Ling Hu Yu-Xuan Wang Zi-Yue Lin Wen-Shuo Ren Bo Liu Hui Zhao Qiong Qin 
Supported by Capital Medical University Scientific Research Grant for Undergraduate Students(No.XSKY2023026).
Age-related macular degeneration(AMD)is a complicated disease that causes irreversible visual impairment.Increasing evidences pointed retinal pigment epithelia(RPE)cells as the decisive cell involved in the progress o...
关键词：NRF2 upstream regulators retinal pigment epithelia age-related macular degeneration oxidative stress 
TMEM63B regulates postnatal development of cochlear sensory epithelia via thyroid hormone signaling
《Journal of Genetics and Genomics》2024年第6期673-676,共4页Chang Ye Tian-Zi Zhang Yan-Yu Zang Yun Stone Shi Guoqiang Wan 
supported by the National Natural Science Foundation of China(82171136 and 81970888 to G.W.,32330044 to Y.S.S.);Fundamental Research Funds for the Central Universities(021414380533toG.W.).
Sound transmission occurs in the cochlea,a complex and ingenious subdivision in the inner ear.The structure of the cochlea develops structurally and functionally by the time before two postnatal weeks(the time of hear...
关键词：COCHLEAR al. SUPPORTING 
Impaired dNKAP function drives genome instability and tumorigenic growth in Drosophila epithelia
《Journal of Molecular Cell Biology》2023年第12期50-64,共15页Ting Guo Chen Miao Zhonghua Liu Jingwei Duan Yanbin Ma Xiao Zhang Weiwei Yang Maoguang Xue Qiannan Deng Pengfei Guo Yongmei Xi Xiaohang Yang Xun Huang Wanzhong Ge 
supported by the National Natural Science Foundation of China(31970668).
Mutations or dysregulated expression of NF-kappaB-activating protein(NKAP)family genes have been found in human cancers.How NKAP family gene mutations promote tumor initiation and progression remains to be determined....
关键词：Drosophila wing imaginal disc dNKAP genome instability tumorigenic growth 
Emerging Therapeutic Strategies in The Fight Against Primary Biliary Cholangitis被引量：1
《Journal of Clinical and Translational Hepatology》2023年第4期949-957,共9页Abigail Medford Jonathan Childs Ashleigh Little Sanjukta Chakraborty Leonardo Baiocchi Gianfranco Alpini Shannon Glaser 
This work was supported by Texas A&M University,College of Medicine,Department of Medical Physiology,Bryan,TX,the NIH grants DK110035,DK129236,and AA028711 to Drs.Alpini,and Glaser,Cancer Prevention&Research Institute of Texas(CPRIT)-RP210213 to Dr.Chakraborty;the Hickam Endowed Chair,Gastroenterology,Medicine,Indiana University,the Indiana University Health-Indiana University School of Medicine Strategic Research Initiative,the Senior Career Scientist Award(IK6 BX004601);the VA Merit award(5I01BX000574)to GA from the United States Department of Veteran’s Affairs,Biomedical Laboratory Research and Development Service.The views expressed in this article are those of the authors and do not necessarily represent the Department of Veterans Affairs views.
The liver has a vital role in many metabolic and regulatory processes in the body.Primary biliary cholangitis(PBC),previously known as primary biliary cirrhosis,is a chronic cholestatic autoimmune disease of the intra...
关键词：Cholestatic liver disease Therapeutic approaches Biliary epithelia ursodeoxycholic acid 
Dynamic RNA profiles in the small intestinal epithelia of cats after Toxoplasma gondii infection
《Infectious Diseases of Poverty》2023年第4期63-82,共20页Bintao Zhai Shi-Chen Xie Jiyu Zhang Jun-Jun He Xing-Quan Zhu 
Project support was kindly provided by the National Key Research and Development Program of China(Grant Nos.2021YFC2300800 and 2021YFC2300802);the National Natural Science Foundation of China(Grant Nos.32172887 and 32102701);the Youth Science and Technology Fund Program of Gansu province(Grant No.23JRRA562);the Innovation Project of Chinese Academy of Agricultural Sciences(Grant No.25-LZIHPS-05);the Agricultural Science and Technology Innovation Program(ASTIP)(Grant No.CAAS-ASTIP-2016-LVRI-03);the Yunnan Expert Workstation(Grant No.202005AF150041);The funding bodies played no role in the design of the study and collection,analysis,and interpretation of data and in writing the manuscript.
Background Felids are the only definitive hosts ofToxoplasma gondii. However, the biological features of the feline small intestine followingT. gondii infection are poorly understood. We investigated the changes in th...
关键词：Toxoplasma gondii Definitive host CAT Small intestinal epithelia Long non-coding RNA Circular RNA MRNA 
Secondary bile acids and the biliary epithelia: The good and the bad被引量：1
《World Journal of Gastroenterology》2023年第2期357-366,共10页Ilaria Lenci Martina Milana Alessandro Signorello Giuseppe Grassi Leonardo Baiocchi 
The biliary tract has been considered for several decades a passive system just leading the hepatic bile to the intestine.Nowadays several researches demonstrated an important role of biliary epithelia(i.e.cholangiocy...
关键词：CHOLANGIOCYTES Biliary secretion CHOLESTASIS Bile acids Secondary bile acids Ursodeoxycholic acid Lithocholic acid 
Poly(ADP-ribose),adherens junctions,vinculin and the actin cytoskeleton:Current evidence,future perspectives and implications
《BIOCELL》2022年第12期2531-2535,共5页LAURA LAFON-HUGHES 
Poly(ADP-ribose)(PAR)is a highly negatively charged polymer.PAR is synthesized by poly(ADP-ribose)polymerases(PARPs)and is involved in the assembly and stabilization of macromolecular complexes.Here,the presence and p...
关键词：PARP TANKYRASE EPITHELIA Neuron Schwann cell CARDIOMYOCYTE VINCULIN 
Identification and characterization of stem cells in mammalian esophageal stratified squamous epithelia
《Journal of Molecular Cell Biology》2022年第6期30-46,共17页Yanan Yang Guodong Deng Lili Qiao Hui Yuan Xiaohong Yu Lei Xu Shih-Hsin Lu Wei Jiang Xiying Yu 
This work was supported by the National Natural Science Foundation of China(NSFC)(81972572 to W.J.);the Chinese Academy of Medical Sciences(CAMS)Innovation Fund for Medical Sciences(CIFMS)(2021-I2M-1-014 to Xiying Yu).
Somatic stem cells are essential for the maintenance of tissue homeostasis. Despite its importance, how the esophageal stratified squamous epithelium executes its self-renewal and maintenance remains elusive. In this ...
关键词：esophageal stem cells hemidesmosomes Wnt signaling HOMEOSTASIS 
Proteomic identification of ruminal epithelial protein expression profiles in response to starter feed supplementation in pre-weaned lambs
《Animal Nutrition》2021年第4期1271-1282,共12页Daming Sun Shengyong Mao Weiyun Zhu Junhua Liu 
supported by the National Natural Science Foundation of China(31501980);National Key Research and Development Plan(2018YFD0501900);project for top young talents program of College of Animal Science and Technology of Nanjing Agricultural University(DKQB201904);Postgraduate Research&Practice Innovation Program of Jiangsu Province(KYCX200603)。
The pre sent study aimed to comparatively characterize the ruminal epithelial protein expression profiles in lambs fed ewe milk or milk plus starter diet using proteome analysis.Twenty new-born lambs were randomly div...
关键词：STARTER Rumen epithelium Protein expression Proteomics LAMB 
Inhibition of histamine receptor H3 suppresses the growth and metastasis of human non-small cell lung cancer cells via inhibiting PI3K/Akt/mTOR and MEK/ERK signaling pathways and blocking EMT被引量：2
《Acta Pharmacologica Sinica》2021年第8期1288-1297,共10页Yan-yan Zhao Jing Jia Jing-jing Zhang Yan-ping Xun Shu-jun Xie Jia-feng Liang Hong-gang Guo Jia-zhen Zhu Sheng-lin Ma Shi-rong Zhang 
supported by grants from the National Natural Science Foundation(81602555,81803042);Natural Science Foundation of Zhejiang Province(LQ17H160003,LQ19H280004);Medical and Health Technology project of Zhejiang Province(2018KY580);the Traditional Chinese Medicine Science and Technology Plan of Zhejiang Province(2018ZQ012,2018ZQ013);Social Development Application Project of Hangzhou(20180533B41).
Recent evidence shows that the expression levels of histamine receptor H3(Hrh3)are upregulated in several types of cancer.However,the role of Hrh3 in non-small cell lung cancer(NSCLC)has not been elucidated.In the pre...
关键词：non-small cell lung cancer histamine receptor h3 apoptosis cell migration and invasion epithelia-mesenchymal transition METASTASIS ciproxifan RAMH 
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