POLYMERSOMES

作品数：14被引量：25H指数：3
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相关期刊：《Science China Materials》《Chinese Journal of Polymer Science》《Journal of Biomedical Research》《Bioactive Materials》更多>>
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Bioinspired menstrual blood-derived stem cells-conditioned medium/polymersome nanoparticles for the treatment of carbon tetrachloride-induced acute liver failure in mice
《Aggregate》2024年第4期376-385,共10页Zuhong Li Qian Li Xiaoxi Ouyang Shima Tang Qiuhong Liu Yaqi Zhang Yanhong Zhang Xiaopeng Yu Danhua Zhu Ying Mu Lanjuan Li 
National Key Research and Development Program of China,Grant/Award Numbers:2019YFC0840600,2019YFC0840609;Fundamental Research Funds for the Central Universities,Grant/Award Number:2022ZFJH003;Independent Project Fund of the State Key Laboratory for Diagnosis and Treatment of Infectious Disease。
Acute liver failure is a life-threatening syndrome,for which liver transplantation is presently the most effective treatment.Unfortunately,such treatment is extremely limited by a shortage of donor organs.Stem cell th...
关键词：acute liver failure MenSCs-conditioned medium NANOPARTICLES POLYMERSOMES 
Gas-generating polymersomes-based amplified photoimmunotherapy for abscopal effect and tumor metastasis inhibition被引量：1
《Chinese Chemical Letters》2024年第6期456-461,共6页Chenlu Huang Xinyu Yang Qingyu Yu Linhua Zhang Dunwan Zhu 
financially supported by National Natural Science Foundation of China(Nos.82172090,82302390 and 82072059);CAMS Innovation Fund for Medical Sciences(Nos.2021-I2M-1-058 and 2022-I2M-1-023);China Postdoctoral Science Foundation(No.2022M720502);Tianjin Municipal Natural Science Foundation(No.22JCQNJC00070);CAMS Union Young Scholars Support Program(No.2022051);Fundamental Research Funds for the Central Universities(No.2019PT320028)。
Due to the heterogeneity of tumors,single phototherapy cannot completely ablate tumors and inhibit tumor metastasis.To overcome these,we formulated targeted and multifunctional polymersomes ABC@ICGIMQ-LHRH(AIRL)that e...
关键词：POLYMERSOMES PHOTOTHERAPY Immunotherapy TLR 7/8 agonist Gas-generating 
Folate-targeted co-delivery polymersomes for efficient photo-chemo-antiangiogenic therapy against breast cancer and in vivo evaluation via OCTA/NIRF dual-modal imaging被引量：1
《Chinese Chemical Letters》2022年第12期5035-5041,共7页Hongjun Wu Chenlu Huang Liwei Wang Qinghua Li Yuejie Li Linhua Zhang Dunwan Zhu 
supported by the National Natural Science Foundation of China(Nos.82072059 and 82172090);the Fundamental Research Funds for the Central Universities(No.2019PT320028);Tianjin Municipal Natural Science Foundation(No.20JCYBJC00030);CAMS Initiative for Innovative Medicine(No.2021-I2M-1-058);Science and Technology Planning Project of Tianjin(No.18ZXSGSY00050).
Intelligent nanoplatform that combines multimodal imaging and therapeutic effects holds great promise for precise and efficient cancer therapy.Herein,folate-targeted polymersomes with stimuli-responsiveness were fabri...
关键词：POLYMERSOMES Optical coherence tomography angiography(OCTA) Near infrared fluorescence(NIRF)imaging Photo-chemo-antiangiogenic therapy Intelligent nanoplatform 
Polymersome-mediated cytosolic delivery of cyclic dinucleotide STING agonist enhances tumor immunotherapy被引量：3
《Bioactive Materials》2022年第10期1-11,共11页Huan Zheng Beibei Guo Xinyun Qiu Yifeng Xia Yan Qu Liang Cheng Fenghua Meng Zhiyuan Zhong 
supported by research grants from the National Natural Science Foundation of China(NSFC 52033006,51861145310,51773146 and 51633005)and the National Key R&D Program of China(2021YFB3800900).
Cyclic dinucleotides(CDNs)as stimulator of interferon genes(STING)agonists capable of inducing strong antitumor innate immune response are highly promising for tumor immunotherapy.The efficacy of these CDNs is,however...
关键词：POLYMERSOMES STING agonists Cyclic dinucleotide Immunotherapy Radiotherapy 
Programmed polymersomes with spatio-temporal delivery of antigen and dual-adjuvants for efficient dendritic cells-based cancer immunotherapy被引量：1
《Chinese Chemical Letters》2022年第9期4179-4184,共6页Hanyong Wang Xinyu Yang Chunyan Hu Chenlu Huang Hai Wang Dunwan Zhu Linhua Zhang 
financially supported by National Natural Science Foundation of China (Nos. 82072059 and 82172090);CAMS Initiative for Innovative Medicine (No. 2021-I2M-1-058);the Fundamental Research Funds for the Central Universities (Nos. 2019PT320028 and 2019-0831-03);Tianjin Municipal Natural Science Foundation (No. 20JCYBJC00030)
Since antigen and adjuvant are rapid clearance in vivo,insufficient delivery to induce dendritic cells(DCs)maturation and cross-presentation,as well as limited migration efficiency of DCs to secondary lymph organs,gre...
关键词：DCs vaccine Immunotherapy IMIQUIMOD MPLA DOTAP OVA 
Polymersomes:From Macromolecular Self-Assembly to Particle Assembly被引量：2
《Chinese Journal of Chemistry》2022年第15期1842-1855,共14页Jiamin Zhang Jinhui Jiang Sha Lin Erik Jan Cornel Chang Li Jjianzhong Du 
This work was supported by the National Natural Science Foundation of China(Nos.21925505,52003195,and 22101207);Shanghai International Scientific Collaboration Fund(No.21520710100);the China Postdoctoral Science Foundation(Nos.2019M661614 and 2020M671197);J.D.is a recipient of the National Science Fund for Distinguished Young Scholars.
What is the most favorite and original chemistry developed in your research group?Ring-opening polymerization-induced self-assembly of N-carboxyanhydrides(NCA-PISA),and fusion-induced particle assembly(FIPA).How do yo...
关键词：Polymersomes(polymer vesicles) Nanoparticles Biomedical applications Macromolecular self-assembly Polymerization-induced self-assembly Particle assembly 
Hybrid lipopolymer vesicle drug delivery and release systems被引量：1
《The Journal of Biomedical Research》2021年第4期301-309,共9页Erik Reimhult Mudassar Mumtaz Virk 
the work from the European Research Council under the European Union's Seventh Framework Program(FP/2007-2013)/ERC grant agreement No.310034;the Austrian Science Fund(FWF)grant No.I 3064.
Hybrid lipopolymer vesicles are membrane vesicles that can be self-assembled on both the micro-and nano-scale.On the nanoscale,they are potential novel smart materials for drug delivery systems that could combine the ...
关键词：hybrid vesicles lipopolymersomes POLYMERSOMES drug delivery lipid domains triggered release 
Synthesis and self-assembly of poly(ethylene glycol)-block-poly(N-3-(methylthio)propyl glycine)and their oxidation-sensitive polymersomes被引量：4
《Chinese Chemical Letters》2020年第7期1931-1935,共5页Yangwei Deng Hui Chen Xinfeng Tao Sylvain Trepout Jun Ling Min-Hui Li 
the French National Research Agency(No.ANR16-CE29-0028);the National Natural Science Foundation of China(No.21674091);the Joint Foundation of Shaanxi Province Natural Science Basic Research Program;Shaanxi Coal Chemical Group Co.,Ltd.(No.2019JLM-46)for financial support;the China Scholarship Council for funding his Ph.D.scholarship in France。
Amphiphilic block copolymers poly(ethylene glycol)-block-poly(N-3-(methylthio)propyl glycine)(PEGb-PMeSPG)were synthesized via ring-opening polymerization of N-3-(methylthio)propyl glycine Nthiocarboxyanhydride(MeSPG-...
关键词：Polypeptoid SELF-ASSEMBLY POLYMERSOME Oxidation-responsive Glucose oxidase 
Recent Progress in Fluorescent Vesicles with Aggregation-induced Emission被引量：1
《Chinese Journal of Polymer Science》2019年第4期352-371,I0006,共21页Hui Chen Min-Hui Li 
financially supported by the French National Research Agency (No. ANR-16-CE29-0028);the National Natural Science Foundation of China (Nos. 21604001 and 21528402)
Fluorescent vesicles have recently attracted increasing attention because of their potential applications in bioimaging,diagnostics, and theranostics, for example, in vivo study of the delivery and the distribution of...
关键词：Vesicles POLYMERSOMES Aggregation-induced emission SMALL-MOLECULE amphiphiles AMPHIPHILIC polymers AMPHIPHILIC SUPRAMOLECULES AMPHIPHILIC supramacromolecules 
Efficient and targeted drug/siRNA co-delivery mediated by reversibly crosslinked polymersomes toward anti-inflammatory treatment of ulcerative colitis (UC)被引量：4
《Nano Research》2019年第3期659-667,共9页Xin Xu Weijing Yang Qiujun Liang Yanan Shi Wenxin Zhang Xiao Wang Fenghua Meng Zhiyuan Zhong Lichen Yin 
National Natural Science Foundation of China (Nos. 51573123, 51722305, and 51633005);the Ministry of Science and Technology of China (No. 2016YFA0201200) 111 project;Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD).
Co-delivery of anti-inflammatory siRNA and hydrophilic drug provides a promising approach for the treatment of ulcerative colitis (UC). However, lack of a suitable and efficient co-delivery carrier poses critical chal...
关键词：ULCERATIVE colitis (UC) ANTI-INFLAMMATORY therapy POLYMERSOMES reversible crosslinking siRNA/drug CO-DELIVERY macrophage targeting 
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