PHTHALIDE

作品数：21被引量：46H指数：4
导出分析报告
相关领域：医药卫生更多>>
相关作者：江骥胡蓓李燕赵芊萧淑惠更多>>
相关机构：学研究院AM大学中国医学科学院中国协和医科大学中国医学科学院北京协和医学院更多>>
相关期刊：《Journal of Hainan Medical University》《Journal of Chinese Pharmaceutical Sciences》《国际眼科杂志》《Acta Pharmacologica Sinica》更多>>
相关基金：国家自然科学基金王宽诚敎育基金中国博士后科学基金国家重点基础研究发展计划更多>>
-
在结果中检索

检索结果分析

结果分析中...
共 条 记 录，以下是1-10
全选清除导出
参考文献引证文献引用追踪
视图：
排序：
Exploring the bioactive substances and mechanisms of Chuanxiong Rhizoma treating acute lung injury based on combined network pharmacological,phytochemical,and pharmacological investigations
《Guideline and Standard in Chinese Medicine》2024年第4期182-194,共13页Lintao Xu Xinping Cheng Qingwen Hu Guangcheng Peng Xinyu Qi Yu Zhao Xiaoning Wang Zhenpeng Xu Tao Shen 
supported by NNSF of China(81673558 and 81874341);Shandong Provincial Natural Science Foundation(ZR2023LZY003);Multidisciplinary Research and Innovation Program of Shandong University(No.2020QNQT007);Outstanding Young Scholars Program of Shandong University.
Background:Acute lung injury(ALI)is a high-fatality respiratory disease,and the development of new therapeutic agents is ongoing.Chuanxiong Rhizoma has been prescribed for the therapy of ALI in traditional Chinese med...
关键词：Chuanxiong Rhizoma acute lung injury network pharmacology PHTHALIDE inflammation 
A review:Research progress on multi-target neuroprotective effects of n-butylphthalide extracted from Apium graveolens seeds
《Asian Journal of Traditional Medicines》2024年第5期275-284,共10页Jiahui Huo Jingxian Ren Xiaoxiao Huang Xiaoliang Wang 
Apium graveolens,an annual herb belonging to the family of Apiaceae,is widely distributed in North and South America,Southern Europe,Africa and Asia.Apium graveolens seeds have a rich history in traditional Chinese me...
关键词：Apium graveolens seeds n-butylphthalide central nervous system diseases 
Phthalide-derived oxaspiroangelioic acids A–C with an unprecedented carbon skeleton from an aqueous extract of the Angelica sinensis root head被引量：8
《Chinese Chemical Letters》2021年第10期3257-3260,共4页Youzhe Chen Chengbo Xu Weiping Wang Xiaoliang Wang Qinglan Guo Jiangong Shi 
Financial support from the National Natural Sciences Foundation of China (No.81630094);CAMS Innovation Fund for Medical Science (No.2017-I2M-3-010, China);The Drug Innovation Major Project (Nos.2018ZX09711001-004 and 2018ZX09711001-001, China)。
Three phthalide-derived analogues,oxaspiroangelioic acids A–C(1–3),were isolated as minor components of an aqueous extract of the Angelica sinensis root heads(guitou).Oxaspiroangelioic acids A and B were racemates s...
关键词：UMBELLIFERAE Angelica sinensis Phthalide-derived analogues Oxaspiroangelioic acids A–C 
Microbial transformation for Region-selective Hydroxylation of Z-Butylidenephthalide by Aspergillus niger CGMCC 3.739
《Asian Journal of Traditional Medicines》2021年第4期203-209,共7页Jian Zou Yongheng Wang Zhengqun Zhou Rongrong He Xinsheng Yao Hao Gao 
This work was financially supported by grants from the National Key Research and Development Program of China(2018 YFA0903200/2018YFA0903201);the National Natural Science Foundation of China(81925037/31900284);Chang Jiang Scholars Program(Young Scholar)from the Ministry of Education of China(Hao Gao,2017);National High-level Personnel of Special Support Program(2017RA2259);Local Innovative and Research Teams Project of Guangdong Pearl River Talents Program(2017BT01Y036);K.C.Wong Education Foundation(Hao Gao,2016).
Microbial transformation is a useful tool for structure modification of active natural products.Z-Butylidenephthalide is the main active constituent of Angelica sinensis.In the present work,a pair of new oxidized meta...
关键词：microbial transformation Z-butylidenephthalide Aspergillus niger CGMCC 3.739 region-selective hydroxylation 
Qualitation of Chuanxiong Rhizome essential oil and determination of 3-butylidenephthalide and ligustilide by GC-MS被引量：8
《Journal of Chinese Pharmaceutical Sciences》2021年第5期434-445,共12页Ximei Yan Taixiang Gao Liyao Shi Rui Wang 
Shanxi pharmaceutical comprehensive development and utilization collaborative innovation center project(Grant No.2017JYXT15);Science and technology innovation team project of Shanxi University of Traditional Chinese Medicine(Grant No.2018TD-008);“Basic research project”of Shanxi University of traditional Chinese Medicine(Grant No.2020PY-JC-20)。
Chuanxiong Rhizoma(rhizomes of Ligusticumchuanxiong Hort)is a classical Chinese medicine,and it is usually used for the treatment of cardiovascular diseases.The essential oil is the main active constituent of Chuanxio...
关键词：Ligusticumchuanxiong Hort 3-Butylidenephthalide LIGUSTILIDE GC-MS SIM scanning 
(±)-6-3’a,7-6’-Isowallichilide:A pair of enantiomeric phthalide dimers from Ligusticum chuanxiong with new 6-3’a,7-6’ dimerization sites被引量：3
《Chinese Chemical Letters》2020年第5期1251-1253,共3页Xin Fang Qiang Ma Yi Feng Shuang Liang 
supported by the Shanghai Municipal Commission of Health and Family Planning(No.ZY3-CCCX-3-5001);the Science and Technology Commission of Shanghai Municipality(Nos.14401901400,15DZ2292000);the Expenditure Budget Program of Shanghai Municipal Education Commission(No.2016YSN24);Xinglin Young Talent Program of Shanghai University of Traditional Chinese Medicine。
(+)-6-3’a,7-6’-Isowallichilide and(-)-6-3’a,7-6’-isowallichilide,a pair of enantio meric phthalide dimers featuring new 6-3’a,7-6’dimerization sites,were isolated from Ligusticum chuanxiong.The structures were e...
关键词：Ligusticum chuanxiong Phthalide dimers ENANTIOMERS Dimerization sites 
Effect of butyl phthalide on serum cytokines, soluble apoptosis factors and antioxidant molecules in patients with vascular dementia
《Journal of Hainan Medical University》2017年第3期153-156,共4页Jian-Min Wang Dong-Liang Zhou Hong-Wei Qin Zhi-Wei Li Ying Xu Ying Guan 
Objective:To study the effect of butyl phthalide on serum cytokines, soluble apoptosis factors and antioxidant molecules in patients with vascular dementia. Methods:86 patients with vascular dementia admitted in our h...
关键词：Vascular DEMENTIA BUTYL PHTHALIDE SOLUBLE apoptosis factor ANTIOXIDANT MOLECULE 
Over-expressed human TREK-1 inhibits CHO cell proliferation via inhibiting PKA and p38 MAPK pathways and subsequently inducing G1 arrest被引量：7
《Acta Pharmacologica Sinica》2016年第9期1190-1198,共9页Man ZHANG Hua-jing YIN Wei-ping WANG Jiang LI Xiao-liang WANG 
Aim： Recent studies have shown that the two-pore-domain potassium channel TREK-1 is involved in the proliferation of neural stem cells, astrocytes and human osteoblasts. In this study, we investigated how TREK-1 affe...
关键词：TREK-l CliO cells G1 phase arrest cell proliferation /-butylphthalide PKA p38/MAPK 
Protective effects of dl-3n-butylphthalide against diffuse brain injury被引量：7
《Neural Regeneration Research》2013年第28期2615-2624,共10页Yaning Zhao Jianmin Li Pan Zhang Changxiang Chen Shuxing Li 
supported by the grants from Hebei Province Science and Technology Ministry,No.20276102D;Key Project of Hebei Province Education Ministry,No.ZD2010106
DI-3n-butyiphthalide can effectively treat cerebral ischemia; however, the mechanisms underlying the effects of dl-3n-butylphthalide on microcirculation disorders following diffuse brain injury remain unclear. In this...
关键词：neural regeneration brain injury diffuse brain injury blood-brain barrier brain edema vasculardensity cerebral blood flow vascular permeability brain water content grants-supported paper NEUROREGENERATION 
Chinese herbal extract dl-3n-butylphthalide A commonly used drug for the treatment of ischemic stroke as a novel therapeutic approach to treat neurodegenerative diseases被引量：3
《Neural Regeneration Research》2011年第35期2773-2778,共6页Wenfang He Wensheng Zhou Zhiping Hu 
the Undergraduate Creative Program of Central South University,No. 081053358;the Education Expenditure of Hunan Provincial Finance Department,No. 2010163;the Key Frontier Research Project of Central South University (from 2010 to 2011)
DI-3n-butylphthalide is the active component isolated from the seeds of Apium graveolens Linn. A number of pharmacological and clinical studies have proven that dl-3n-butylphthalide is highly potent and multi-targeted...
关键词：3-N-BUTYLPHTHALIDE ischemic stroke neurodegenerative diseases traditional Chinese medicine 
全选清除导出
共3页<123>
检索报告 对象比较 聚类工具 使用帮助 返回顶部