BIOCERAMICS

作品数：67被引量：154H指数：6
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相关领域：医药卫生化学工程更多>>
相关作者：邬鸿马兴涛杨明理更多>>
相关机构：四川大学更多>>
相关期刊：《World Journal of Clinical Cases》《Bioactive Materials》《Journal of Biosciences and Medicines》《Journal of Materials Science & Technology》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划重庆市自然科学基金瑞士科学基金更多>>
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Two decades of continuous progresses and breakthroughs in the field of bioactive ceramics and glasses driven by CICECO-hub scientists
《Bioactive Materials》2024年第10期104-147,共44页H.R.Fernandes S.Kannan M.Alam G.E.Stan A.C.Popa R.Buczy′nski P.Gołębiewski J.M.F.Ferreira 
the project No.2021/43/P/ST7/02418 cofunded by the National Science Centre and the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 945339;JMFF,RB,PG gratefully acknowledge the financial support provided by the Polish National Science Centre for the POLONEZ BIS 1“BAGBONE”,Project no.536651.JMFF would like to thank all the national and international research collaborators for their valuable contributions,especially for the papers covered in this review article;the scope of the project CICECOAveiro Institute of Materials,UIDB/50011/2020,UIDP/50011/2020&LA/P/0006/2020,financed by national funds through the FCT/MCTES(PIDDAC);the Department of Health Research–Indian Council of Medical Research[DHR-ICMR];India[Reference:R.11013/28/2021-GIA/HR dated November 25,2021]is recognized by SK and MA.GES and ACP are thankful to the Core Program of the National Institute of Materials Physics within the National Research Development and Innovation Plan 2022–2027,carried out with the support of the Romanian Ministry of Research,Innovation and Digitalization under the project PC2-PN23080101.
Over the past two decades, the CICECO-hub scientists have devoted substantial efforts to advancing bioactiveinorganic materials based on calcium phosphates and alkali-free bioactive glasses. A key focus has been thede...
关键词：CaP bioceramics Alkali-free bioactive glasses Bio-functional doping/substitution OSSEOINTEGRATION Antimicrobial efficiency 
Magnesium-containing bioceramics stimulate exosomal miR-196a-5p secretion to promote senescent osteogenesis through targeting Hoxa7/MAPK signaling axis被引量：5
《Bioactive Materials》2024年第3期14-29,共16页Lei Qi Xin Fang Jinge Yan Cancan Pan Weiwen Ge Jing Wang Steve GF.Shen Kaili Lin Lei Zhang 
support National Natural Science Foundation of China(No.81970973);Science and Technology Commission of Shanghai Municipality(No.20ZR1432200,21140900102,21490711700,22010502600);Disciplinary Characteristic Biobank Project of Ninth People’s Hospital affiliated to Shanghai Jiao Tong University School of Medicine(No.YBKB202110);Cross Disciplinary Research Fund of Shanghai Ninth People’s Hospital,Shanghai JiaoTong University School of Medicine(No.JYJC202219);Shanghai’s Top Priority Research Center(No.2022ZZ01017);CAMS Innovation Fund for Medical Sciences(No.CIFMS,2019-I2M-5-037).
Stem cell senescence is characterized by progressive functional dysfunction and secretory phenotypic changes including decreased proliferation,dysfunction of osteogenic and angiogenic differentiation,increased secreti...
关键词：MAGNESIUM AKERMANITE Senescent osteogenesis Exosomal miR-196a-5p Hoxa7/MAPK axis 
Li-Mg-Si bioceramics provide a dynamic immuno-modulatory and repair-supportive microenvironment for peripheral nerve regeneration被引量：3
《Bioactive Materials》2023年第10期227-242,共16页Yiting Sun Hongjian Zhang Yu Zhang Zheqi Liu Dongming He Wanlin Xu Siyi Li Chenping Zhang Zhen Zhang 
supported by a grant from the National Natural Science Foundation of China(81900968);Shanghai Sailing Program(20YF1409900);Shanghai Anticancer Association EYAS PROJECT(SACA-CY21A01 and SACA-CY22A01).
Biomaterials can modulate the local immune and repair-supportive microenvironments to promote peripheral nerve regeneration. Inorganic bioceramics have been widely used for regulating tissue regeneration and local imm...
关键词：Peripheral nerve regeneration BIOCERAMICS Immuno-modulation microenvironment MACROPHAGE Nerve guidance conduit 
Bioceramic scaffolds with triply periodic minimal surface architectures guide early-stage bone regeneration被引量：1
《Bioactive Materials》2023年第7期374-386,共13页Miaoda Shen Yifan Li Fengling Lu Yahui Gou Cheng Zhong Shukun He Chenchen Zhao Guojing Yang Lei Zhang Xianyan Yang Zhongru Gou Sanzhong Xu 
The authors would like to acknowledge financial support from the National Key Research and Development Program of China(2017YFE0117700);National Natural Science Foundation of China(82172419,81902225,81871775);Natural Science Foundation of Zhejiang Province(LGF21H060006,LZ22E020002,LQ23H060005,LQ23H150004);Zhejiang Province Public Welfare Technology Application Research Project(LGF22E030002).
The pore architecture of porous scaffolds is a critical factor in osteogenesis,but it is a challenge to precisely configure strut-based scaffolds because of the inevitable filament corner and pore geometry deformation...
关键词：Pore geometry Bone regeneration efficiency Triply periodic minimal surface Biodegradable bioceramics Tissue engineering 
Multi-layer-structured bioactive glass nanopowder for multistage-stimulated hemostasis and wound repair被引量：3
《Bioactive Materials》2023年第7期319-332,共14页Yidan Wang Meng luo Ting Li Chenxi Xie Sihua Li Bo Lei 
This work was supported by the Special Support Program for High Level Talents of Shaanxi Province of China,the key R&D plan of Shaanxi Province of China(grant No.2021GXLH-Z-052);State Key Laboratory for Manufacturing Systems Engineering of China(grant No.sklms2021006);Young Talent Support Plan of Xi’an Jiaotong University of China(grant No.QY6J003).
Current treatments for full-thickness skin injuries are still unsatisfactory due to the lack of hierarchically stimulated dressings that can integrate the rapid hemostasis,inflammation regulation,and skin tissue remod...
关键词：Bioactive materials BIOCERAMICS Bioactive glass nanoparticles Wound repair 
Osteoporotic bone recovery by a bamboo-structured bioceramic with controlled release of hydroxyapatite nanoparticles被引量：6
《Bioactive Materials》2022年第11期379-393,共15页Rui Zhao Tieliang Shang Bo Yuan Xiangdong Zhu Xingdong Zhang Xiao Yang 
This project was funded by National Natural Science Foundation of China(grant no.81971755);Sichuan Science and Technology Program(2020YFS0038);Fundamental Research Funds for the Central Uni-versities.We thank Dr.Li Chen from the Analytical&Testing Center of Sichuan University for assistance with micro-CT images.
While most bone defects can be repaired spontaneously,the healing process can be complicated due to insuf-ficient bone regeneration when osteoporosis occurs.Synthetic materials that intrinsically stimulate bone for-ma...
关键词：Nano hydroxyapatite BIOCERAMICS OSTEOGENESIS Bone regeneration OSTEOPOROSIS 
Next-generation finely controlled graded porous antibacterial bioceramics for high-efficiency vascularization in orbital reconstruction被引量：1
《Bioactive Materials》2022年第10期334-345,共12页Jingyi Wang Yiyu Peng Menglu Chen Xizhe Dai Lixia Lou Changjun Wang Zhaonan Bao Xianyan Yang Zhongru Gou Juan Ye 
support from the National Natural Science Foundation of China(81870635,82000948);the National Key Research and Development Program of China(2017YFE0117700)and Natural Science Foundation of Zhejiang Province(LY20H120007).
Eyeball loss due to severe ocular trauma,intraocular malignancy or infection often requires surgical treatment called orbital implant reconstruction to rehabilitate the orbital volume and restore the aesthetic appeara...
关键词：Graded porous scaffolds Fibro-vascularization ANTIBACTERIAL Hardystonite Orbital implants 
CD301b^(+) macrophages mediate angiogenesis of calcium phosphate bioceramics by CaN/NFATc1/VEGF axis被引量：2
《Bioactive Materials》2022年第9期446-455,共10页Jiaolong Wang Qin Zhao Liangliang Fu Shihang Zheng Can Wang Litian Han Zijian Gong Ziming Wang Hua Tang Yufeng Zhang 
supported by the National Natural Science Foundation of China(82025011 and 82100975);the China National Postdoctoral Program for Innovative Talents(BX2021227);the Young Elite Scientist Support Program by CSA(2020PYRC001);the Fundamental Research Funds for the Central Universities(2042021kf0181 and 2042020kf0204).
Calcium phosphate(CaP)bioceramics are important for tissue regeneration and immune response,yet how CaP bioceramics influence these biological processes remains unclear.Recently,the role of immune cells in biomaterial...
关键词：Calcium phosphate ceramics MACROPHAGE ANGIOGENESIS CD301b CALCINEURIN 
Effect of minor amounts of β-calcium pyrophosphate and hydroxyapatite on the physico-chemical properties and osteoclastic resorption of β-tricalcium phosphate cylinders被引量：3
《Bioactive Materials》2022年第4期222-235,共14页B.Le Gars Santoni L.Niggli S.Dolder O.Loeffel G.A.Sblendorio R.Heuberger 
the Swiss National Science Foundation for its funding(Grant no.200021_169027).
β-Tricalcium Phosphate(β-TCP),one of the most used bone graft substitutes,may contain up to 5 wt%foreign phase according to standards.Typical foreign phases includeβ-calcium pyrophosphate(β-CPP)and hydroxyapatite(...
关键词：BIOCERAMICS Calcium phosphate β-Tricalcium phosphate β-Calcium pyrophosphate HYDROXYAPATITE Osteoclastic resorption 
Mn-containing bioceramics inhibit osteoclastogenesis and promote osteoporotic bone regeneration via scavenging ROS被引量：15
《Bioactive Materials》2021年第11期3839-3850,共12页Jianmei Li Cuijun Deng Wanyuan Liang Fei Kang Yun Bai Bing Ma Chengtie Wu Shiwu Dong 
the Key Program of National Natural Science Foundation of China(81930067);the Youth Program of National Natural Science Foundation of China(grant number 82002316);the Youth Cultivation Project of Army Medical University(2020XQN08);General Program of Natural Science Foundation of Chongqing(cstc2019jcyj-msxmX0176).
Osteoporosis is caused by an osteoclast activation mechanism.People suffering from osteoporosis are prone to bone defects.Increasing evidence indicates that scavenging reactive oxygen species(ROS)can inhibit receptor ...
关键词：Mn-containing bioceramics Antioxidant biomaterials OSTEOCLASTOGENESIS ROS Osteoporotic bone regeneration 
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