云南高校图书馆联盟文献共享服务平台- AQUAPORIN-4

AQUAPORIN-4: 作品数：63被引量：217H指数：9; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：沙洛林李红闪史彦芳郭毅马睿泽更多>>; 相关机构：南京医科大学中山大学附属第三医院河北大学北华大学更多>>; 相关期刊：《World Journal of Neurology》《Neural Regeneration Research》《中国药理通讯》《神经损伤与功能重建》更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划广东省自然科学基金北京市自然科学基金更多>>

Functional abnormalities of the glymphatic system in cognitive disorders: 《Neural Regeneration Research》2025年第12期3430-3447,共18页Wuyue Shentu Qi Kong Yier Zhang Wenyao Li Qiulu Chen Sicheng Yan Junjun Wang Qilun Lai Qi Xu Song Qiao; supported by Zhejiang Provincial Medical and Health Science and Technology Project,Nos.2022KY008(to JW),2023KY001(to JW),2023KY006(to QL);Zhejiang Provincial Traditional Chinese Medicine Science and Technology Project,No.2023ZL220(to QL)。; Various pathological mechanisms represent distinct therapeutic targets for cognitive disorders,but a balance between clearance and production is essential for maintaining the stability of the brain's internal environm...; 关键词：AQUAPORIN-4 ASTROCYTE cerebrospinal fluid dynamics cognitive disorders glymphatic system

Characteristic changes in astrocyte properties during astrocyte-to-neuron conversion induced by NeuroD1/Ascl1/Dlx2: 《Neural Regeneration Research》2025年第6期1801-1815,共15页Qing He Zhen Wang Yuchen Wang Mengjie Zhu Zhile Liang Kanghong Zhang Yuge Xu Gong Chen; supported by the Key Project of Guangzhou City,No.202206060002;Science and Technology Project of Guangdong Province,No.2018B030332001;Guangdong Provincial Pearl River Project,No.2021ZT09Y552 (all to GC)。; Direct in vivo conversion of astrocytes into functional new neurons induced by neural transcription factors has been recognized as a potential new therapeutic intervention for neural injury and degenerative disorders....; 关键词：AQUAPORIN-4 Ascl1 ASTROCYTE cortex Dlx2 gap junction glia-to-neuron conversion neural regeneration NeuroD1 REPROGRAMMING

Aquaporin-4-IgG-seropositive neuromyelitis optica spectrum disorders:progress of experimental models based on disease pathogenesis: 《Neural Regeneration Research》2025年第2期354-365,共12页Li Xu Huiming Xu Changyong Tang; Neuromyelitis optica spectrum disorders are neuroinflammatory demyelinating disorders that lead to permanent visual loss and motor dysfunction.To date,no effective treatment exists as the exact causative mechanism rem...; 关键词：AQUAPORIN-4 experimental model neuromyelitis optica spectrum disorder PATHOGENESIS

Glymphatic system:a gateway for neuroinflammation: 《Neural Regeneration Research》2024年第12期2661-2672,共12页Kailu Zou Qingwei Deng Hong Zhang Changsheng Huang; supported by the National Natural Science Foundation of China,Nos.82071249 and 81771207 (both to CH)。; The glymphatic system is a relatively recently identified fluid exchange and transpo rt system in the brain.Accumulating evidence indicates thatglymphatic function is impaired not only in central nervous system disord...; 关键词：AQUAPORIN-4 central nervous system disease cerebrospinal fluid chronic neuroinflammation glymphatic dysfunction NEURODEGENERATION peripheral nerve injury perivascular space systemic disease vicious cycle

Biomarkers for neuromyelitis optica:a visual analysis of emerging research trends被引量：3: 《Neural Regeneration Research》2024年第12期2735-2749,共15页Xiangjun Li Jiandong Zhang Siqi Zhang Shengling Shi Yi’an Lu Ying Leng Chunyan Li; Neuromyelitis optica is an inflammatory demyelinating disease of the central nervous system that differs from multiple sclerosis.Over the past 20 years,the search for biomarke rs for neuromyelitis optica has been ongo...; 关键词：AQUAPORIN-4 AUTOANTIBODY multiple sclerosis myelin oligodendrocyte glycoprotein antibody-associated disease neuromyelitis optica neuromyelitis optica spectrum disorder optical coherence tomography

Anti-aquaporin-4 antibody(AQP4-IgG)and anti-myelin oligodendrocyte glycoprotein antibody(MOG-IgG)in the cerebrospinal fluid被引量：1: 《Neural Regeneration Research》2024年第5期949-950,共2页Tetsuya Akaishi Tatsuro Misu; In the last decade,a new neurological disease concept known as anti-myelin oligodendrocyte glycoprotein antibody(MOG-IgG)-associated disease(MOGAD)has emerged and is currently one of the most focused research areas in...; 关键词：AQP4 MYELIN

The lymphatic drainage systems in the brain:a novel target for ischemic stroke?被引量：6: 《Neural Regeneration Research》2023年第3期485-491,共7页Ying-Jie Wang Yan-Rong Sun Yan-Hong Pei Hao-Wen Ma Ya-Kun Mu Li-Hua Qin Jun-Hao Yan; supported by the Natural Science Foundation of Beijing(Key Program);No.Z200025(to JHY);the National Natural Science Foundation of China,No.81873818(to LHQ);Supporting Platform Construction Project of Peking University Health Science Center,No.BMU2021ZC011(to JHY).; Recent studies have proposed three lymphatic drainage systems in the brain,that is,the glymphatic system,the intramural periarterial drainage pathway,and meningeal lymphatic vessels,whose roles in various neurological...; 关键词：AQUAPORIN-4 BRAIN edema glymphatic system intramural periarterial drainage ischemic stroke lymphatic drainage meningeal lymphatic vessels neuroinflammation neurotoxicity

Anti-inflammatory effect of miR-125a-5p on experimental optic neuritis by promoting the differentiation of Treg cells被引量：3: 《Neural Regeneration Research》2023年第2期451-455,共5页Jia-Lin Zhan Yan-Ling Huang Qiao-Wen Liang Xiao-Sheng Qu Zi-Mei Dong Yi Du Wen-Jing Luo; supported by the National Natural Science Foundation of China,No.81560162;the Guangxi Natural Science Foundation of China,No.2018GXNSFAA050052(both YD)。; Methylprednisolone pulse treatment is currently used fo r optic neuritis.It can speed visual recovery,but does not improve the ultimate visual outcomes.Recent studies have repo rted that miR-125 a-5 p has immunomodula...; 关键词：AQUAPORIN-4 CORTICOSTEROIDS inflammation microRNA NEUROPROTECTION OLIGODENDROCYTE optic neuropathy regulatory T cells Th17 cell visual field defect

Aquaporin 4 deficiency eliminates the beneficial effects of voluntary exercise in a mouse model of Alzheimer’s disease被引量：8: 《Neural Regeneration Research》2022年第9期2079-2088,共10页Yun Liu Pan-Pan Hu Shuang Zhai Wei-Xi Feng Rui Zhang Qian Li Charles Marshall Ming Xiao Ting Wu; supported by the National Natural Science Foundation of China,No.81772454(to TW);Natural Science Foundation of Jiangsu,China,No.BK20190655(to QL).; Regular exercise has been shown to reduce the risk of Alzheimer’s disease(AD).Our previous study showed that the protein aquaporin 4(AQP4),which is specifically expressed on the paravascular processes of astrocytes,i...; 关键词：Alzheimer’s disease AMYLOID-BETA ASTROCYTES AQUAPORIN-4 glymphatic system learning and memory synaptic protein transgenic mice voluntary exercise

Glymphatic imaging and modulation of the optic nerve被引量：1: 《Neural Regeneration Research》2022年第5期937-947,共11页Anisha Kasi Crystal Liu Muneeb A.Faiq Kevin C.Chan; supported by National Institutes of Health,No.R01-EY028125;Bright Focus Foundation,No.G2019103;Feldstein Medical Foundation;Research to Prevent Blindness/Stavros Niarchos Foundation International Research Collaborators Award;an unrestricted grant from Research to Prevent Blindness to NYU Langone Health Department of Ophthalmology(to KCC)。; Optic nerve health is essential for proper function of the visual system.However,the pathophysiology of certain neurodegenerative disease processes affecting the optic nerve,such as glaucoma,is not fully understood.Re...; 关键词：AQUAPORIN-4 cerebrospinal fluid glaucoma glymphatic system HYDROCEPHALUS IMAGING metabolic waste clearance optic nerve PERIVASCULAR pharmacological and lifestyle interventions

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