PITAVASTATIN

作品数：13被引量：20H指数：3
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相关领域：医药卫生化学工程更多>>
相关作者：董金华武芳莉齐谢敏更多>>
相关机构：沈阳药科大学中国药科大学军事医学科学院更多>>
相关期刊：《Current Medical Science》《Journal of Pharmaceutical Analysis》《Acta Pharmacologica Sinica》《Cardiovascular Innovations and Applications》更多>>
相关基金：国家自然科学基金更多>>
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Lowering of Blood Lipid Levels with a Combination of Pitavastatin and Ezetimibe in Patients with Coronary Heart Disease: A Meta-Analysis
《Cardiovascular Innovations and Applications》2022年第4期41-55,共15页Ruping Cai Chen Chang Xingjie Zhong Qiang Su 
Objectives:According to the findings of randomized controlled trials,blood lipid levels in patients with coronary heart disease(CHD)can be significantly decreased through a combination of pitavastatin and ezetimibe;ho...
关键词：PITAVASTATIN EZETIMIBE Coronary heart disease Blood lipid 
Effects of Pitavastatin on Lipoprotein Subfractions and Oxidized Low-density Lipoprotein in Patients with Atherosclerosis被引量：4
《Current Medical Science》2020年第5期879-884,共6页Rui-xia XU Yan ZHANG Yue ZHANG Ya-ru WU Xiao-lin LI Yuan-lin GUO Geng LIU Qian DONG Jian-jun LI 
This work was supported,in part,by Capital Special Foundation of Clinical Application Research(No.Z121107001012015);Capital Health Development Fund(No.201614035);CAMS Major Collaborative Innovation Project(No.2016-I2M-1-011);PUMC Youth Fund(No.3332018200).
It has been demonstrated that pitavastatin can significantly reduce low-density lipoprotein(LDL)cholesterol(LDL-C),but its impact on lipoprotein subfractions and oxidized low-density lipoprotein(oxLDL)has not been det...
关键词：PITAVASTATIN ATHEROSCLEROSIS lipoprotein subfraction low-density lipoprotein 
Pitavastatin attenuates AGEs-induced mitophagy via inhibition of ROS generation in the mitochondria of cardiomyocytes被引量：7
《The Journal of Biomedical Research》2018年第4期281-287,共7页Zhimin Zha Junhong Wang Shiling Li Yan Guo 
supported by the National NaturalScience Foundation of China(NSFC 81570328,Wang Junhong);the"Sixth-Peak Talent"of Jiangsu Province(2011WSN-029 to Prof.Guo Yan and2013WSN-036 to Dr.Wang Junhong);support by the Health Department of Jiangsu Province(z201301)
This study aimed to investigate whether pitavastatin protected against injury induced by advanced glycation end products products（AGEs） in neonatal rat cardiomyocytes,and to examine the underlying mechanisms.Cardiom...
关键词：advanced glycation end products（AGEs） receptor for advanced glycation end products（RAGE） PITAVASTATIN autophagy mitochondrial oxidation oxidative stress 
Electrochemical determination of an anti-hyperlipidimic drug pitavastatin at electrochemical sensor based on electrochemically pre-treated polymer film modified GCE被引量：1
《Journal of Pharmaceutical Analysis》2017年第4期258-264,共7页Umar J.Pandit Gowhar A.Naikoo Mehraj Ud Din Sheikh Gulzar A.Khan K.K.Raj S.N.Limaye 
An electrochemically pretreated silver macroporous(Ag MP) multiwalled carbon nanotube modified glassy carbon electrode(PAN-Ag MP-MWCNT-GCE) was fabricated for the selective determination of an antihyperlipidimic drug,...
关键词：PITAVASTATIN Electrochemical sensor ADSORPTIVE STRIPPING VOLTAMMETRY Biological fluids PHARMACEUTICAL formulations 
LCeMS/MS assay for pitavastatin in human plasma and subsequent application to a clinical study in healthy Chinese volunteers
《Asian Journal of Pharmaceutical Sciences》2014年第6期348-355,共8页Tengrui Yin Qian Liu Hui Zhao Lirong Zhao Hui Liu Miao Li Meilan Cui Wengang Ren 
This work was supported by Qidu Pharmaceutical Co.,LTD(Zibo,China).
Arapid,selective and sensitive liquid chromatography-tandem massspectrometry(LC-MS/MS)method has been developed and validated for the determination of pitavastatin in humanplasma.Following a liquid-liquid extraction,b...
关键词：PITAVASTATIN PHARMACOKINETICS Liquid chromatography tandem mass spectrometry 
Effects of Pitavastatin on the Intima-Media Thickness of the Carotid Artery in Patients with Ischemic Stroke: The Pitavastatin Efficacy Study on Surrogate Markers and Imaging for Stroke (PESSMIST)
《World Journal of Neuroscience》2014年第4期306-312,共7页Yasushi Shibata 
Pitavastatin is a strong statin that was developed in Japan. The clinical impact of pitavastatin treatment in patients with ischemic stroke has not been reported. We conducted a prospective, open label, clinical case-...
关键词：PITAVASTATIN STROKE ECHO IMT HYPERLIPIDEMIA 
降胆固醇药匹伐他汀(pitavastatin)在欧洲上市
《齐鲁药事》2010年第10期613-613,共1页
关键词：降胆固醇药 匹伐他汀 欧洲 上市 欧盟市场 市场销售 审批程序 药品审批 
Lack of effect of genetic polymorphisms of SLCO1B1 on the lipid-lowering response to pitavastatin in Chinese patients被引量：3
《Acta Pharmacologica Sinica》2010年第3期382-386,共5页Guo-ping YANG Hong YUAN Bin TANG Wei ZHANG Lian-sheng WANG Zhi-jun HUANG Dong-sheng OU-YANG Gui-xiang ZHANG Hong-hao ZHOU 
Aim： To investigate the SLCO1B1 388A〉G and 521T〉CC polymorphisms in hyperlipidemia patients and evaluate the effect of the two polymorphisms on the lipid-lowering efficacy of pitavastatin.Methods： The functional p...
关键词：essential hyperlipidemia POLYMORPHISM SLCO1B1 PITAVASTATIN 
匹伐他汀钙(pitavastatin)被引量：2
《中国药物化学杂志》2010年第2期155-155,共1页武芳莉 董金华 
关键词：匹伐他汀钙 PITAVASTATIN 他汀类降脂药 2009年 胆固醇水平 FDA批准 制药公司 商品名 
Degradation Pathway for Pitavastatin Calcium by Validated Stability Indicating UPLC Method
《American Journal of Analytical Chemistry》2010年第2期83-90,共8页Antony Raj Gomas Pannala Raghu Ram Nimmakayala Srinivas Jadi Sriramulu 
Degradation pathway for pitavastatin calcium is established as per ICH recommendations by validated and stability indicating reverse phase liquid chromatographic method. Pitavastatin is subjected to stress conditions ...
关键词：COLUMN Liquid CHROMATOGRAPHY PITAVASTATIN CALCIUM FORCED Degradation Validation Stability Indicating 
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