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Antidepressant and anti-nociceptive effects of Nigella sativa and its main constituent,thymoquinone:A literature review: 《Asian Pacific Journal of Tropical Biomedicine》2022年第12期495-503,共9页Akbar Anaeigoudari; Medicinal plants and their ingredients have beneficial effects on human health.Nigella sativa is a herbal plant with multiple biological and pharmacological activities.Previous studies demonstrated the anti-inflammato...; 关键词：Nigella sativa THYMOQUINONE ANTIDEPRESSANT ANTI-NOCICEPTIVE Depression ANTI-INFLAMMATORY Sickness behaviors Pain

Pharmacological insights into Chukrasia velutina bark:Experimental and computer-aided approaches被引量：1: 《Animal Models and Experimental Medicine》2022年第4期377-388,共12页Israt Jahan Shahenur Alam Sakib Najmul Alam Mohuya Majumder Sanjida Sharmin A.S.M.Ali Reza; Background:Chukrasia velutina is an enthnomedicinally used plant reported to have significant medicinal values.The present study aimed to explore the pharmacological activities of bark methanol extract using in vitro,...; 关键词：ANTI-NOCICEPTIVE antioxidant ANTIPYRETIC Chukrasia velutina CYTOTOXICITY

Curculigo recurvata W.T.Aiton exhibits anti-nociceptive and anti-diarrheal effects in Albino mice and an in silico model: 《Animal Models and Experimental Medicine》2020年第2期169-181,共13页Shabbir Ahmad Mst.Samima Nasrin A.S.M.Ali Reza Nishan Chakrabarty Md.Akramul Hoque Sanjida Islam Mohammad Shah Hafez Kabir Syed Mohammed Tareq A.H.M.Khurshid Alam Md.Areeful Haque Md.Saiful Islam Arman; Center for Research and Publication,Grant/Award Number 180111;International Islamic University Chittagong。; Background: Curculigo recurvata(C. recurvata) is an enthnomedicinally important herb reported to have significant medicinal values. The present study aimed to explore the in vivo and in silico anti-nociceptive and ant...; 关键词：ANALGESIC anti-diarrheal ANTI-NOCICEPTIVE curculigine Curculigo recurvata isocurculigine

Anti-nociceptive Effect of Patchouli Alcohol: Involving Attenuation of Cyclooxygenase 2 and Modulation of Mu-Opioid Receptor被引量：3: 《Chinese Journal of Integrative Medicine》2019年第6期454-461,共8页YU Xuan WANG Xin-pei YAN Xiao-jin JIANG Jing-fei LEI Fan XING Dong-ming GUO Yue-ying DU Li-jun; Supported by the National Natural Science Foundation of China(No.81374006 and No.81073092);the Special Foundation for New Drug Innovation of Tsinghua University(No.20142000077),China; Objective: To explore the anti-nociceptive effect of patchouli alcohol(PA), the essential oil isolated from Pogostemon cablin(Blanco) Bent, and determine the mechanism in molecular levels. Methods: The acetic acid-ind...; 关键词：Chinese MEDICI ne patchouli ALCOHOL an algesic EFFECT mu-opioid receptor cyclooxyge nase 2

NO-cGMP-K channel-dependent anti-nociceptive activities of methanol stem bark extract of Piptadeniastrum africanum(Mimosaceae) on rats: 《Asian Pacific Journal of Tropical Biomedicine》2018年第3期150-159,共10页Mbiantcha Marius Almas Jabeen Ateufack Gilbert Shabana U.Simjee Bomba Tatsinkou Francis Desire Nida Dastagir; supported by the TWAS(Academy of Science of Developing Countries);International Center for Chemical and Biological Sciences;University of Karachi,under the Postdoctoral Fellowship Award to Mbiantcha Marius(RF N°:3240280477); Objective: To explore anti-hyperalgesic properties of methanol extract of Piptadeniastrum africanum stem bark(PAME) and it possible action mechanism. Methods: PAME was tested on carrageenan ?induced hyperalgesia using...; 关键词：Piptadeniastrum africanum Neuropathic pain Inflammatory pain CGMP Nitric oxide

Electroacupuncture at Fengchi(GB20) inhibits calcitonin gene-related peptide expression in the trigeminovascular system of a rat model of migraine被引量：12: 《Neural Regeneration Research》2017年第5期804-811,共8页Luo-peng Zhao Lu Liu Pei Pei Zheng-yang Qu Yu-pu Zhu Lin-peng Wang; supported by the National Natural Science Foundation of China,No.81603683;a grant from the National Basic Research Program of China,No.2014CB543203;a grant from the Beijing Municipal Science&Technology Commission of China,No.Z171100001017033; Most migraine patients suffer from cutaneous allodynia; however, the underlying mechanisms are unclear. Calcitonin gene-related peptide（CGRP） plays an important role in the pathophysiology of migraine, and it is the...; 关键词：nerve regeneration ELECTROACUPUNCTURE MIGRAINE calcitonin gene-related peptide cutaneous allodynia ANTI-NOCICEPTIVE FENGCHI trigeminal ganglion neural regeneration

Effect of SRD-P401 on the Discomfort of Neck and/or Shoulder Stiffness: 《American Journal of Plant Sciences》2017年第5期1065-1076,共12页Akira Iizuka Maasa Sonoda Ruka Goto Tokunori Matsui Chiaki Kudoh Katsumi Kido Yasuhiro Komatsu; SRD-P401 is a newly developed healthy food supplement which has an anti-inflammatory and analgesic effect. In this report, the effects of SRD-P401 on neck and shoulder stiffness were assessed by an inquiry method in t...; 关键词：SUPPLEMENT ANTI-INFLAMMATORY ANTI-NOCICEPTIVE SRD-P401

Protective effects of crude and alkaloidal extracts of Tamarindus indica against acute inflammation and nociception in rats: 《Journal of Acute Disease》2017年第2期78-81,共4页Ali Audu Jigam Fatima Mahmood Bashir Lawal; Objective: To investigate the anti-inflammatory and antinociceptive effects of total alkaloids extracted from the leaf of Tamarindus indica (T. indica) in rats. Methods:Acetic acid-induced pain and egg albumin-induced...; 关键词：Tamarindus INDICA ANTI-INFLAMMATORY ANTI-NOCICEPTIVE Secondary METABOLITE

The anti-nociceptive effect of bufalin,an active ingredient from toad venom via modulating voltage-gated sodium channels: 《中国药理学与毒理学杂志》2016年第10期1046-1046,共1页SHEN Rui XU Jian YIN Pei-hao TAO Jie; The project supported by Innovation Program of Shanghai Municipal Education Commission(15ZZ063);by Research Project of Putuo Hospital,Shanghai University of Traditional Chinese Medicine(2014YJ002); OBJECTIVE Toad venom(Venenum Bufonis)isalways used for analgesia in China from ancient to modern times,but the effective component of it remains unclear.METHODS In the present study,we investigated the anti-nociceptiv...; 关键词：BUFALIN sodium channels formalin test carrageenan test patch clamp

Anti-nociceptive roles of the glia-specific metabolic inhibitor fluorocitrate in paclitaxel- evoked neuropathic pain被引量：3: 《Acta Biochimica et Biophysica Sinica》2016年第10期902-908,共7页Yongming Xu Guangxia Cheng Yanrong Zhu Xin Zhang Shaofeng Pu Junzhen Wu Yingying Lv Dongping Du; This work was supported by a grant from the National Natural Science Foundation of China （No. 81370933）.; Paclitaxel （Taxol） is a powerful chemotherapy drug used in breast cancers, but it often causes neuropathic pain, leading to the early cessation of therapy and poor treatment outcomes. Approaches for the management o...; 关键词：neuropathic pain FLUOROCITRATE ASTROCYTE PACLITAXEL

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