supported by the National Science Foundation of China (81701191, 82301720);Natural Science Foundation of Chongqing (CSTB2022NSCQ-MSX0973, CSTB2023NSCQMSX0183, CSTB2023NSCQ-BHX0214);China Postdoctoral Science Foundation (2022M722384, 2023MD734128);the Joint Project of Chongqing Health Commission and Science and Technology Bureau (2020FYYX104);Chongqing Postdoctoral Special Support Foundation (2023CQBSHTB2010);Chongqing Postdoctoral Science Foundation (CSTB2023NSCQ-BHX0214);the First Affiliated Hospital of Chongqing Medical University Postdoctoral Science Foundation (CYYY-BSHPYXM-202310);CQMU Program for Youth Innovation in Future Medicine (W0168)。
Although disturbances in the gut microbiome have been implicated in multiple sclerosis(MS), little is known about the changes and interactions between the gut microbiome and blood metabolome, and how these changes aff...
To the Editor,Coronavirus disease 2019(COVID-19)-related acute respiratory distress syndrome(ARDS)is biologically and clinically heterogeneous with a broad spectrum of organ dysfunction and illness severity.[1] In COV...
supported by the National Natural Science Foundation of China(No.81770759 and No.82270806);Innovation Project of Guangxi Graduate Education(No.YCBZ2022094).
Chronic prostatitis/chronic pelvic pain syndrome(CP/CPPS)is a complex disease that is often accompanied by mental health disorders.However,the potential mechanisms underlying the heterogeneous clinical presentation of...
supported financially by the Research and Demonstration of Precision Functional Compound Feed Technology of Major Cultured Fishes and Shrimps in South China,China(2021B0202050002);the Department of Education of Guangdong Province,China(2021ZDZX4005);the China Agriculture Research System of MOF and MARA,China(CARS-47).
With the increasing incorporation of plant-based ingredients into the grouper diet,the issue of aflatoxin B1 (AFB1) contamination in the diet has become a significant concern.In this study,the negative effects of AFB1...
Objective This study aims to analyze metabolites in the cerebrospinal fluid(CSF)of neurosyphilis patients to identify potential diagnostic markers.Methods Untargeted metabolomics by liquid chromatography-mass spectrom...
supported by the National Natural Science Foundation of China(32302258,32172317);Changsha Municipal Natural Science Foundation(kq2202223).
Diabetes-associated cognitive dysfunction has already been attracted considerable attention.Advanced glycation end products(AGEs)from daily diets are thought to be a vital contributor to the development of this diseas...
This work was supported by the grants from the Zhejiang Provincial Traditional Chinese Medicine Science and Technology Project(No.2022ZB273);the Huadong Medicine Joint Funds of the Zhejiang Provincial Natural Science Foundation of China(No.LHDMY24H270002);the Zhejiang Provincial Medical and Health Technology Project(No.2023KY158);the Cultivation Program for Excellent Young Talents of Hangzhou First People’s Hospital(No.YQNYC202131);the Science and Technology Special Project of Hangzhou Biomedicine and Health Industry Development Support(No.2021WJCY253).
Diabetic nephropathy(DN)is a severe complication of diabetes and the leading cause of end-stage renal disease and death.Germacrone(Ger)possesses anti-inflammatory,antioxidant and anti-DN properties.However,it is uncle...
supported by grants from the National Natural Science Foundation of China(81870610);Shanghai Science and Technology Commission Foundation(21Y11904800 and 23ZR1451500);the Clinical Research Plan of SHDC(SHDC2020CR3065B);the National Key Research and Development Program of China(2021YFC2501600 and 2021YFC2501601).
Gestational diabetes mellitus(GDM)is a pregnancy-related metabolic disorder associated with short-term and long-term adverse health outcomes,but its pathogenesis has not been clearly elucidated.Investigations of the d...
Supported by the Innovation Platform for Academicians of Hainan Province,No.YSPTZX202313;Hainan Province Clinical Medical Center,No.2021818;Hainan Provincial Health Industry Research Project,No.22A200078;Hainan Provincial Postgraduate Innovation Research Project,No.Qhyb2022-133;Hainan Medical University Graduate Student Innovative Research Project,No.HYYB2022A18;Nanjing Medical University Fan Daiming Research Funds for Holistic Integrative Medicine,No.2020-3HIM.
BACKGROUND Fecal microbiota transplantation(FMT)is a promising therapeutic approach for treating Crohn’s disease(CD).The new method of FMT,based on the automatic washing process,was named as washed microbiota transpl...
funded by the Natural Science Foundation of Beijing(7212023);the National Natural Science Foundation of China(82071180)to HHM;the National Natural Science Foundation of China(82271206)to TZL。
Objective Postoperative delirium(POD)has become a critical challenge with severe consequences and increased incidences as the global population ages.However,the underlying mechanism is yet unknown.Our study aimed to e...