NANOPROBES

作品数:75被引量:171H指数:6
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相关领域:医药卫生理学更多>>
相关作者:孙正博吴爱国喻学锋李娟更多>>
相关机构:华东理工大学武汉大学上海交通大学中国科学院宁波材料技术与工程研究所更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划福建省自然科学基金中国博士后科学基金更多>>
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Persistent luminescence encoding for rapid and accurate oral-derived bacteria identification
《Chinese Chemical Letters》2025年第1期459-463,共5页Chaohui Zheng Jing Xi Shiyi Long Tianpei He Rui Zhao Xinyuan Luo Na Chen Quan Yuan 
financially supported by Quanzhou high-level Talents Project Fund(No.2022C033R);the National Natural Science Foundation of China(Nos.21925401,52221001);the Fundamental Research Funds for the Central Universities(No.2042022rc0004);the Postdoctoral Innovative Research of Hubei Province of China(No.211000025);the interdisciplinary innovative talents foundation from Renmin Hospital of Wuhan University。
The dysbiosis of oral microbiota contributes to diseases such as periodontitis and certain cancers by triggering the host inflammatory response.Developing methods for the immediate and sensitive identification of oral...
关键词:Oral microorganisms Persistent luminescent nanoprobes Optical sensing array Fingerprint physicochemical properties Linear discriminant analysis 
Naked-eye visualization of lymph nodes using fluorescence nanoprobes in non-human primate-animal models
《Nano Research》2024年第8期7404-7414,共11页Xiaoyuan Ji Binbin Chu Xiaofeng Wu Zhiming Xia Airui Jiang Chenyu Wang Zhiming Chen Danni Zhong Qiaolin Wei Bin Song Wanlin Li Yiling Zhong Houyu Wang Fenglin Dong Min Zhou Yao He 
the National Natural Science Foundation of China(Nos.21825402,31400860,22393932,T2321005,and 22204117);the Science and Technology Development Fund,Macao SAR(Nos.0002/2022/AKP and 0115/2023/RIA2);the National Key R&D Program of China(No.2023YFB3208200);the Natural Science Foundation of Jiangsu Province of China(Nos.BK20191417 and BK20170061);the Program for Jiangsu Specially Appointed Professors to Y.H.,a project funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD);111 Project and Collaborative Innovation Center of Suzhou Nano Science and Technology(NANO-CIC).
Despite sufficient studies performed in non-primate animal models,there exists scanty information obtained from pilot trials in non-human primate animal models,severely hindering nanomaterials moving from basic resear...
关键词:fluorescent silicon nanoparticles lymph node REAL-TIME naked-eye visualization macaque models 
Enzymatically controlled DNA tetrahedron nanoprobes for specific imaging of ATP in tumor
《Chinese Chemical Letters》2024年第8期221-224,共4页Xiaohong Wen Mei Yang Lie Li Mingmin Huang Wei Cui Suping Li Haiyan Chen Chen Li Qiuping Guo 
supported by the National Natural Science Foundation of China(Nos.21877030,21735002,21778016).
Intracellular ATP is an emerging biomarker for cancer early diagnosis because it is a key messenger for regulating the proliferation and migration of cancer cells.However,the conventional ATP biosensing strat-egy is o...
关键词:Enzyme-controlled APE1 DNA tetrahedron Cancer-specific ATP biosensing 
Afterglow Nanoprobes for In-vitro Background-free Biomarker Analysis
《Chemical Research in Chinese Universities》2024年第2期213-224,共12页ZHENG Ting WANG Ying LI Xianming LI Chenghui WU Peng 
supported by the National Natural Science Foundation of China(No.22325403);the Open Research Fund of School of Chemistry and Chemical Engineering,Henan Normal University,China(No.2022A02).
Accurate detection of biomarkers is essential for disease diagnosis.Although the highly sensitive fluorescence probes are feasible for the above goal,it is typically interfered by the auto-fluorescence and light scatt...
关键词:Photochemical afterglow In-vitro analysis Background-free detection BIOMARKER 
Matthew effect:General design strategy of ultra-fluorogenic nanoprobes with amplified dark–bright states in aggregates
《Aggregate》2024年第2期482-492,共11页Shinsuke Segawa Xinwen Ou Tianruo Shen Tomohiro Ryu Yuki Ishii Herman H.Y.Sung Ian D.Williams Ryan T.K.Kwok Ken Onda Kiyoshi Miyata Xuewen He Xiaogang Liu Ben Zhong Tang 
Hong Kong PhD Fellowship Scheme,Grant/Award Number:PF18-15484;National Natural Science Foundation of China,Grant/Award Numbers:21788102,22274106;Research Grants Council of Hong Kong,Grant/Award Numbers:16306620,16303221,N_HKUST609/19,C6014-20W;Innovation and Technology Commission,Grant/Award Number:ITC-CNERC14SC01;Shenzhen Science and Technology Innovation Committee;JSPS KAKENHI,Grant/Award Numbers:JP23H01977,JP23H04631;JST the establishment of university fellowships towards the creation of science technology innovation,Grant/Award Number:JPMJFS2132。
Fluorescence imaging,a key technique in biological research,frequently utilizes fluorogenic probes for precise imaging in living systems.Tetrazine is an effective emission quencher in fluorogenic probe designs,which c...
关键词:aggregation-induced emission bioorthogonal chemistry click chemistry fluorescence imaging TETRAZINE 
Advances in nanoprobes-based immunoassays
《BMEMat(BioMedical Engineering Materials)》2024年第1期49-75,共27页Lusi Zhang Bin Huang Jing Jin Yan Li Ning Gu 
National Natural Science Foundation of China,Grant/Award Numbers:51832001,61821002;Natural Science Foundation of Jiangsu Province,Grant/Award Number:BK20222002;Nanjing Science and Technology Development Foundation,Grant/Award Number:202205066。
Immunoassay is a powerful technique that uses highly specific antigenantibody interactions to detect biochemical targets such as proteins and toxins.As a diagnostic tool,immunoassay is employed in the screening,diagno...
关键词:detection range IMMUNOASSAY limit of detection NANOPROBES 
Precise diagnosis of cardiac‐cerebral vascular diseases with magnetic resonance imaging‐based nanoprobes
《iRADIOLOGY》2024年第3期264-284,共21页Wenyue Li Ruru Zhang Xinyi Zhang Shuai Wu Tiancong Ma Yi Hou Jianfeng Zeng Mingyuan Gao 
National Natural Science Foundation of China(NSFC),Grant/Award Numbers:22177115,81720108024,82130059;National Key Research and Development Program of China,Grant/Award Number:2018YFA020880。
Cardiac‐cerebral vascular diseases(CCVDs)are acknowledged as a major threat to public health,leading to more than one‐third of all deaths worldwide.The complex anatomical structure and immune features of blood vesse...
关键词:ANGIOGRAPHY CARDIOVASCULAR DISEASES CEREBROVASCULAR DISEASES magnetic resonance imaging NANOPROBE 
Rare earth fluorescent nanoprobes with minimal side effects enable tumor microenvironment activation for chemotherapy
《Journal of Rare Earths》2024年第2期256-262,I0001,共8页Tianqi Cao Yuxin Liu Qi Jia Xiaolu Wang Shouqiang Zhang Jing Zhou 
Project supported by the National Natural Science Foundation of China(92159103);Beijing Municipal Education Commission Outstanding Young Individual Project(CIT&TCD201904082);Youth High-level Talent Project of Capital Normal University(20530810024);Yanjing Young Scholar Program of Capital Normal University。
Chemotherapy,the use of antitumor drugs to kill cancer cells,is currently one of the most effective treatments for cancer.However,serious toxic side effects caused by long-term drug accumulation can cause significant ...
关键词:Rare earth nanoprobes Fluorescence Ratiometric imaging DOX CHEMOTHERAPY 
D-type neuropeptide decorated AIEgen/RENP hybrid nanoprobes with light-driven ROS generation ability for NIR-Ⅱ fluorescence imaging-guided through-skull photodynamic therapy of gliomas被引量:1
《Aggregate》2024年第1期185-195,共11页Xuelu He Yuan Luo Yanying Li Yuanbo Pan Ryan T.K.Kwok Lulu He Xiaolin Duan Pengfei Zhang Aiguo Wu Ben Zhong Tang Juan Li 
Natural Science Foundation of China,Grant/Award Numbers:T2222021,32011530115,32025021;National Key R&D Programs,Grant/Award Number:2019YFE0198700;Science and Technology Bureau of Ningbo City,Grant/Award Numbers:2020Z094,2021Z072;Excellent Member of Youth Innovation Promotion Association Foundation of CAS,Grant/Award Number:Y2021079;Innovation and Technology Commission,Grant/Award Number:MHP/047/19。
Glioma is one of the most common malignant tumors of the central nervous system,leading high mortality rates in human.Aggregation-induced emission(AIE)photosensitizers-based photodynamic therapy(PDT)has emerged as a p...
关键词:aggregation-induced emission D-type neuropeptide glioma photodynamic therapy rare-earth doping nanoparticles 
Imaging-guided precision oncotherapy mediated by nanoprobes: From seeing to curing
《Chinese Chemical Letters》2024年第1期116-128,共13页Jie Zheng Shi-Hui Chen Biao Huang Mingxi Zhang Quan Yuan Ran Cui 
the National Key R&D Program of China(No.2020YFA0908800);the National Natural Science Foundation of China(Nos.22174105 and 21974104);Large-scale Instrument and Equipment Sharing Foundation of Wuhan University.
Malignant tumors are the main diseases threatening human life. Using precise theranostics to diagnose and cure tumors has emerged as a new method to improve patient survival. Based on the current development of precis...
关键词:Precise theranostics Imaging-guided Tumor surgical navigation Chemodynamic therapy Phototherapy NANOPROBES 
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