NANOPROBE

作品数：72被引量：113H指数：5
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相关领域：医药卫生理学更多>>
相关作者：曲扬屈凌波吴爱国董业民陶晓峰更多>>
相关机构：南方科技大学复旦大学上海交通大学医学院附属第九人民医院中国科学院更多>>
相关期刊：《Science Bulletin》《Bioactive Materials》《Journal of Rare Earths》《Science China(Life Sciences)》更多>>
相关基金：国家自然科学基金广东省自然科学基金福建省自然科学基金国家重点基础研究发展计划更多>>
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Ultra-broadband near-field Josephson microwave microscopy
《National Science Review》2025年第2期44-50,共7页Ping Zhang Yang-Yang Lyu Jingjing Lv Zihan Wei Shixian Chen Chenguang Wang Hongmei Du Dingding Li Zixi Wang Shoucheng Hou Runfeng Su Hancong Sun Yuan Du Li Du Liming Gao Yong-Lei Wang Huabing Wang Peiheng Wu 
supported by the National Key Research and Development Program of China(2021YFA0718802 and 2018YFA0209002);the National Natural Science Foundation of China(61727805,62288101,62101243,62274086 and 62201396);Jiangsu Provincial Key Laboratory of Advanced Manipulating Technique of Electromagnetic Wave,China Postdoctoral Science Foundation;Jiangsu Funding Program for Excellent Postdoctoral Talent.
Advanced microwave technologies constitute the foundation of a wide range of modern sciences,including microwave integrated circuits,quantum computing,microwave photonics,spintronics,etc.To facilitate the design of ch...
关键词：Josephson junction NANOPROBE near-field microwave frequency mixing 
Strength through unity:Alkaline phosphatase-responsive AIEgen nanoprobe for aggregation-enhanced multi-mode imaging and photothermal therapy of metastatic prostate cancer
《Chinese Chemical Letters》2025年第2期261-268,共8页Ze Wang Hao Liang Annan Liu Xingchen Li Lin Guan Lei Li Liang He Andrew K.Whittaker Bai Yang Quan Lin 
supported by Natural Science Foundation of Jilin Province(No.SKL202302002);Key Research and Development project of Jilin Provincial Science and Technology Department(No.20210204142YY);The Science and Technology Development Program of Jilin Province(No.2020122256JC);Beijing Kechuang Medical Development Foundation Fund of China(No.KC2023-JX-0186BQ079);Talent Reserve Program(TRP),the First Hospital of Jilin University(No.JDYY-TRP-2024007)。
Prostate cancer(PCa)is characterized by high incidence and propensity for easy metastasis,presenting significant challenges in clinical diagnosis and treatment.Tumor microenvironment(TME)-responsive nanomaterials prov...
关键词：AIE Prostate cancer ALP responsive Enhanced multi-mode imaging Enhanced photothermal therapy 
Bifunctional nanoprobe for simultaneous detection of intracellular reactive oxygen species and temperature in single cells
《Microsystems & Nanoengineering》2024年第6期161-172,共12页Yanmei Ma Weikang Hu Jian Hu Muyang Ruan Jie Hu Ming Yang Yi Zhang Hanhan Xie Chengzhi Hu 
supported by the National Key Technologies R&D Program of China(Grant No.2023YFC2415900);Guangdong Basic and Applied Basic Research Foundation(No.2024A1515011915,No.2022A1515010098);partly supported by the Science,Technology,and Innovation Commission of Shenzhen Municipality under grant no.ZDSYS20200811143601004;in part by the Stable Support Plan Program of Shenzhen Natural Science Fund under grant 20220815104331001.
Living cells can rapidly adjust their metabolic activities in response to external stimuli,leading to fluctuations in intracellular temperature and reactive oxygen species(ROS)levels.Monitoring these parameters is ess...
关键词：METABOLISM simultaneous holds 
A Biomimetic Membrane-Coated Nanoprobe for the Ratiometric Fluorescence Detection of Phospholipase A_(2)
《Journal of Analysis and Testing》2024年第3期270-277,共8页Xingyu He Yuanyuan Dong Pan He Chenghui Liu Wei Ren 
supported by the National Natural Science Foundation of China(21904083);the Program for Changjiang Scholars and Innovative Research Team in University(IRT_15R43);the Fundamental Research Funds for the Central Universities(GK202201009,GK202101001,and GK202305001);the Innovation Capability Support Program of Shaanxi Province(2021TD-42).
Phospholipase A_(2)(PLA_(2))is a critical biomarker of many diseases.Among various fluorescent probes,the ratiometric ones have shown great promise because they can provide built-in calibration to avoid interference f...
关键词：Biomimetic membrane Ratiometric nanoprobe Energy transfer Phospholipase A_(2) 
Upconversion-based chiral nanoprobe for highly selective dual-mode sensing and bioimaging of hydrogen sulfide in vitro and in vivo被引量：2
《Light(Science & Applications)》2024年第9期1878-1887,共10页Yang Lu Xu Zhao Dongmei Yan Yingqian Mi Peng Sun Xu Yan Xiaomin Liu Geyu Lu 
supported by the National Key R&D Program of China(No.2023YFB3208303);The National Natural Science Foundation of China(No.62171194);Natural Science Foundation of Jilin Province(No.20210101380JC,20220204130YY and 20230204082YY).
Chiral assemblies have become one of the most active research areas due to their versatility,playing an increasingly important role in bio-detection,imaging and therapy.In this work,chiral UCNPs/CuxOS@ZIF nanoprobes a...
关键词：CHIRAL sulfide DONOR 
A nitroreductase-responsive nanoprobe with homogeneous composition and high loading for preoperative non-invasive tumor imaging and intraoperative guidance
《Chinese Chemical Letters》2024年第7期313-318,共6页Jingqi Xin Shupeng Han Meichen Zheng Chenfeng Xu Zhongxi Huang Bin Wang Changmin Yu Feifei An Yu Ren 
supported by the National Natural Science Foundation of China(Nos.51903201,82172798);the Natural Science Foundation of Shaanxi Province(No.2023-YBSF-270);the Open Program of NHC Key Laboratory of Nuclear Medicine and Jiangsu Key Laboratory of Molecular Nuclear Medicine(No.KF202203);Horizontal Project of the First Affiliated Hospital of Xi'an Jiaotong University(No.202304174)。
Tumor microenvironment(TME)-activatable probes have been proven to effectively increase signal-tobackground ratios(SBRs)and improve the success rate of complete tumor resection.However,many fluorescence probes have to...
关键词：NITROREDUCTASE Tumor diagnosis Intraoperative guidance Self-assembly NANOPROBE 
The hard X-ray nanoprobe beamline at the SSRF
《Nuclear Science and Techniques》2024年第7期79-88,共10页Yan He Hui Jiang Dong-Xu Liang Zhi-Sen Jiang Huai-Na Yu Hua Wang Cheng-Wen Mao Jia-Nan Xie Ai-Guo Li 
National Key Research and Development Program(No.2021YFA1601000);National Natural Science Foundation of China(No.12175294);Natural Science Foundation of Shanghai,China(No.21ZR1471500).
The hard X-ray nanoprobe beamline BL13U is a phase-Ⅱ beamline project at the Shanghai Synchrotron Radiation Facility.The beamline aims to enable comprehensive experiments at high spatial resolutions ranging from 50 t...
关键词：Shanghai synchrotron radiation facility Hard X-ray nanoprobe X-ray nanofocusing 
利用探针跳跃式扫描离子电导显微镜技术揭示结直肠癌单细胞层面对H_(2)O_(2)良性应激的动态响应
《Science Bulletin》2024年第12期1909-1919,共11页王东 Emily Woodcock 杨羲 Hiromi Nishikawa Elena V.Sviderskaya Masanobu Oshima Christopher Edwards 张彦军 Yuri Korchev 
supported by Japan Society for the Promotion of Science KAKENHI(21H01770,22K04890);the World Premier International Research Center Initiative(WPI),MEXT,Japan。
Colorectal cancer(CRC),a widespread malignancy,is closely associated with tumor microenvironmental hydrogen peroxide(H_(2)O_(2))levels.Some clinical trials targeting H_(2)O_(2)for cancer treatment have revealed its pa...
关键词：SPM NANOPROBE NANOBIOLOGY SECM ROS STIFFNESS 
Advances in nanoprobes-based immunoassays
《BMEMat(BioMedical Engineering Materials)》2024年第1期49-75,共27页Lusi Zhang Bin Huang Jing Jin Yan Li Ning Gu 
National Natural Science Foundation of China,Grant/Award Numbers:51832001,61821002;Natural Science Foundation of Jiangsu Province,Grant/Award Number:BK20222002;Nanjing Science and Technology Development Foundation,Grant/Award Number:202205066。
Immunoassay is a powerful technique that uses highly specific antigenantibody interactions to detect biochemical targets such as proteins and toxins.As a diagnostic tool,immunoassay is employed in the screening,diagno...
关键词：detection range IMMUNOASSAY limit of detection NANOPROBES 
Precise diagnosis of cardiac‐cerebral vascular diseases with magnetic resonance imaging‐based nanoprobes
《iRADIOLOGY》2024年第3期264-284,共21页Wenyue Li Ruru Zhang Xinyi Zhang Shuai Wu Tiancong Ma Yi Hou Jianfeng Zeng Mingyuan Gao 
National Natural Science Foundation of China(NSFC),Grant/Award Numbers:22177115,81720108024,82130059;National Key Research and Development Program of China,Grant/Award Number:2018YFA020880。
Cardiac‐cerebral vascular diseases(CCVDs)are acknowledged as a major threat to public health,leading to more than one‐third of all deaths worldwide.The complex anatomical structure and immune features of blood vesse...
关键词：ANGIOGRAPHY CARDIOVASCULAR DISEASES CEREBROVASCULAR DISEASES magnetic resonance imaging NANOPROBE 
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