DIPEPTIDE

作品数：56被引量：81H指数：4
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相关领域：理学医药卫生更多>>
相关作者：叶文才王峥涛徐珞珊徐国钧卢艳花更多>>
相关机构：北京大学中国药科大学重庆科技学院中国科学院大学更多>>
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相关基金：国家自然科学基金中国博士后科学基金国家重点基础研究发展计划国家高技术研究发展计划更多>>
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Biopolymer Decorated Pencil Graphite Electrode for the In-situ Quantification of L-Tryptophan in Dietary Supplements
《Journal of Analysis and Testing》2025年第1期82-95,共14页V.Devika P.J.Sreelekshmi B.Vedhanarayanan Sandhya Sadanandan R.Rejithamol 
A simplistic and novel electrochemical sensor for selectively detecting the essential amino acid tryptophan in dietary supplements was fabricated on a pencil graphite electrode modified with a tryptophan-based dipepti...
关键词：TRYPTOPHAN DIPEPTIDE ELECTROPOLYMERIZATION Electrochemical sensor VOLTAMMETRY 
Recent research of peptide-based hydrogel in nervous regeneration
《Bioactive Materials》2024年第10期503-523,共21页Chunmei Xie Yueyang Chen Lang Wang Kin Liao Bin Xue Yulong Han Lan Li Qing Jiang 
supported by the National Natural Science Foundation of China(32271408,32271296,12202193);National Basic Research Program of China(2021YFA1201404);Natural Science Foundation of Jiangsu Province(BK20232023);Nanjing Health Technology Development Special Project(JQX23002);Jiangsu Provincial Key Medical Center Foundation,Jiangsu Provincial Medical Outstanding Talent Foundation,the Youth Innovation Team of Shaanxi Universities,China.
Neurological disorders exert significantly affect the quality of life for patients,necessitating effective strategies for nerve regeneration.Both traditional autologous nerve transplantation and emerging therapeutic a...
关键词：SELF-ASSEMBLED DIPEPTIDE Cyclic dipeptide HYDROGELS Nervous regeneration 
ALS-linked C9orf72 dipeptide repeats inhibit starvation-induced autophagy through modulating BCL2–BECN1 interaction
《Acta Pharmaceutica Sinica B》2024年第5期2026-2038,共13页Shiqiang Xu Qilian Ma Junwen Shen Ningning Li Shan Sun Nana Wang Yang Chen Chunsheng Dong Kin Yip Tam Jochen H.M.Prehn Hongfeng Wang Zheng Ying 
This work was supported by the National Natural Science Foundation of China(Nos.82022022,32371018 and 82071274);a Project Funded by Jiangsu Key Laboratory of Neuropsychiatric Diseases(BM2013003,China);a Key Project of Natural Science Foundation of Jiangsu Provincial Higher Education Institutions(23KJA310005,China);a Project Funded by the Interdisciplinary Basic Frontier Innovation Program of Suzhou Medical College of Soochow University(MP13202823,China);a Project Funded by the Suzhou International Joint Laboratory for Diagnosis and Treatment of Brain Diseases,and a Project Funded by the Priority Academic Program Development of the Jiangsu Higher Education Institutes(PAPD).J.H.M.P.was supported Science Foundation Ireland(17/COEN/3474,17/JPND/3455);Q.M.is a recipient of an RCSI International StAR Ph.D.scholarship.N.L.was supported by the Postgraduate Research&Practice Innovation Program of Jiangsu Province.K.Y.T.,was supported by the financial support from the Science and Technology Development Fund,Macao SAR(File no.0062/2021/A,China);University of Macao(File no.MYRG2022-00171-FHS,China).
Growing evidences indicate that dysfunction of autophagy contributes to the disease pathogenesis of amyotrophic lateral sclerosis(ALS)and frontotemporal dementia(FTD),two neurodegenerative disorders.The GGGGCC·GGCCCC...
关键词：Amyotrophic lateral sclerosis Frontotemporal dementia C9orf72 AUTOPHAGY BCL2 BECN1/Beclin 1 Dipeptide repeat Neurodegeneration 
Co-assembled C13-dipeptide hydrogels by Gallic Acid (CA) and epigallocatechin gallate (EGCG) with antibacterial activity
《Food Bioscience》2022年第5期933-940,共8页Tan Hu Siyi Pan 
supported by China Agriculture Research System of MOF and MARA(CARS-26-07B);Fundamental Research Funds for the Central Universities(2662019PY016,2662020SPPY011);Hubei Province Technology Innovation Special Major Project(2018ABA072).
The self-assembled peptide-based hydrogels have been widely utilized in foods.However,the self-assembled hydrogels still have some shortages such as low mechanical properties and hydrogel stabilities.Herein,we designe...
关键词：Peptide hydrogels C_(13)-dipeptides Co-assembly Antibacterial activity 
Preparation of conductive and transparent dipeptide hydrogels for wearable biosensor被引量：4
《Bio-Design and Manufacturing》2022年第1期153-162,共10页Yafeng Jing Anhe Wang Jieling Li Qi Li Qingquan Han Xuefang Zheng Hongyu Cao Shuo Bai 
the Beijing Municipal Natural Science Foundation (No. 7212206);the National Natural Science Foundation of China (Nos. 21774132, 22072155, 22002170, 21571025, and 21601025);Project of Young Science and Technology Star of Dalian (No. 2017RQ156).
Conductive and transparent dipeptide hydrogels are desirable building blocks to prepare soft electronic devices and wearable biosensors due to their excellent biocompatibility,multi-functionality,and physiochemical pr...
关键词：Conductivity Transparency Peptide hydrogel Polypyrrole-polydopamine nanoparticles Wearable biosensor 
Detachment-Independent Cationic-Dipeptide Beacons:Reduced False-Negative Signal and Accelerated Fluorescent Lighting in Cell Imaging
《Journal of Analysis and Testing》2022年第1期19-26,共8页Guang-Wei Fu Guo-Yan Luo Xiao-Xuan Li Zhen Zou Yan-Li Lei Zhi-He Qing Jue-Wen Liu Rong-Hua Yang 
supported in part by the financial support through the National Natural Science Foundation of China(22074008,91853104,21735001,21705010);the Natural Science Foundation of Hunan Province(2019JJ30025).
Nanocarriers have been developed to deliver DNA probes into cells for imaging analysis and improving their nuclease resist-ance.However,we found obvious lowered sensitivity and even false-negative results in the tradi...
关键词：Cationic dipeptide nanoparticles DNA probe False-negative signal Fluorescence Cell imaging 
Structurally defined tandem-responsive nanoassemblies composed of dipeptide-based photosensitive derivatives and hypoxia-activated camptothecin prodrugs against primary and metastatic breast tumors被引量：1
《Acta Pharmaceutica Sinica B》2022年第2期952-966,共15页Mengchi Sun Hailun Jiang Tian Liu Xiao Tan Qikun Jiang Bingjun Sun Yulong Zheng Gang Wang Yang Wang Maosheng Cheng Zhonggui He Jin Sun 
supported by National Natural Science Foundation of China,Nos.81773656 and U1608283;Liaoning Revitalization Talents Program,No.XLYC1808017;Key Projects of Technology Bureau in Shenyang,No.18400408;Key projects of Liaoning Province Department of Education,No.2017LZD03;China Postdoctoral Science Foundation(No.2020M680986)。
Substantial progress in the use of chemo-photodynamic nano-drug delivery systems(nanoDDS) for the treatment of the malignant breast cancer has been achieved. The inability to customize precise nanostructures, however,...
关键词：Chemo-photodynamic Tandem-responsive Both-in-one co-nanoassembly Computational simulations CAMPTOTHECIN Pyropheophorbide Reactive oxygen species Breast tumor metastasis 
Gas-Induced Phase Transition of Dipeptide Supramolecular Assembly被引量：2
《CCS Chemistry》2021年第11期8-16,共9页Huimin Xue Jinbo Fei Aoli Wu Xia Xu Junbai Li 
The authors gratefully acknowledge the financial support for this research from the National Nature Science Foundation of China(nos.21961142022,21872150,and 22072160);J.F.particularly thanks to the Youth Innovation Promotion Association of CAS(no.2016032);Institute of Chemistry,CAS(no.Y6290512B1).
The manipulation of supramolecular assembly enables single-component architectures to possess diverse structures and functions.Here,we report directed phase transitions of dipeptide supramolecular gel to crystals with...
关键词：supramolecular assembly PEPTIDE GEL CRYSTAL phase transition 
Origins of catalyst-controlled enantiodivergent hydroamination of enones with pyridazinones:A computational study
《Chinese Chemical Letters》2021年第9期2769-2772,共4页Xiangwei Ren Hongli Wu Mei Zhang Wentao Zhao Genping Huang 
supported by the National Natural Science Foundation of China(Nos.22073066,21503143 and 21975179);the Natural Science Foundation of Tianjin(No.16JCQNJC05600)。
Density functional theory calculations have been performed to investigate the dipeptide phosphinecatalyzed hydroamination of enones with pyridazinones.The computations reveal that a number of the N-H...O hydrogen-bond...
关键词：Dipeptide phosphine catalyst HYDROAMINATION Mechanism Selectivity DFT calculations 
Role of the C9ORF72 Gene in the Pathogenesis of Amyotrophic Lateral Sclerosis and Frontotemporal Dementia被引量：1
《Neuroscience Bulletin》2020年第9期1057-1070,共14页Zongbing Hao Rui Wang Haigang Ren Guanghui Wang 
supported by the National Natural Science Foundation of China (31871023 and 31970966);the National Key Scientific R&D Program of China (2016YFC1306000);a Project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions。
Since the discovery of the C9ORF72 gene in2011,great advances have been achieved in its genetics and in identifying its role in disease models and pathological mechanisms;it is the most common genetic cause of amyotro...
关键词：Amyotrophic lateral sclerosis Frontotemporal dementia C9ORF72 Dipeptide repeat proteins Pathological inclusions 
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