funded by the National Natural Science Foundation of China(XFY 82271492).
Epilepsy,characterized by recurrent seizures,is influenced by biological rhythms,such as circadian,seasonal,and menstrual cycles.These rhythms affect the frequency,severity,and timing of seizures,although the precise ...
This review delved into the intricate relationship between circadian clocks and physiological processes,emphasizing their critical role in maintaining homeo-stasis.Orchestrated by interlocked clock genes,the circadian...
supported by grants from the National Natural Science Foundation of China(No.81874195,82173144);the Natural Science Foundation of Hunan Province(No.2020JJ4769);the Fundamental Research Funds for the Central Universities of Central South University(No.2021zzts0925);the Open-End Fund for the Valuable and Precision Instruments of Central South University(No.CSUZC202237).
Circadian rhythm refers to the inherent 24-h cycle oscillation of biochemical,phys-iological and behavioral functions,which is almost universal in eukaryotes.At least 14 core clock genes have been reported to form mul...
This study was supported by the National Natural Science Foundation of China(grant No.81974099,82170785,81974098,and 82170784);a program from Science and Technology Department of Sichuan Province(grant No.21GJHZ0246);Young Investigator Award of Sichuan University 2017(grant No.2017SCU04A17);Technology Innovation Research and Development Project of Chengdu Science and Technology Bureau(2019-YF05-00296-SN);Sichuan University-Panzhihua Science and Technology Cooperation Special fund(2020CDPZH-4).
The circadian clock is an evolutionary molecular product that is associated with better adaptation to changes in the external environment.Disruption of the circadian rhythm plays a critical role in tumorigenesis of ma...
This work was supported by the Clinical Research Plan of SHDC(SHDC2020CR3066B)。
Evidence about the interaction between circadian rhythms(CR)and epilepsy has been expanded with the application of advanced detection technology.An adequate understanding of how circadian system and epilepsy interact ...
supported by the National Natural Science Foundation of China (No.81473151);the Priority Academic Program Development of Jiangsu Higher Education Institutions
The clinical manifestations of variant angina is unevenly distributed during the 24 h, thusthe in vivo performance of drugs should be tailored according to the angina circadianrhythm. Cryptotanshinone(CTN) is one of t...
Circadian rhythms are daily oscillations of multiple biological processes. Recently, relationships between circadian rhythms and immune functions have also been described. In a mouse sepsis model, the death rate due t...
Circadian rhythms refer to the endogenous rhythms that are generated to synchronize physiology and behavior with 24-h environmental cues. These rhythms are regulated by both external cues and molecular clock mechanism...
The present study was undertaken to 1) formulate a pulsatile colonic delivery of simvastatin (SIM) as chronotherapy for treatment of hypercholesterolemia, and 2) enhance the dissolution profile of the prepared SIM chr...
supported by Project of Training Plan of Shanghai Outstanding Young Clinical Talents of Traditional Chinese Medicine(ZYSNXD011-RC-XLXX-20110006)
To introduce two cases with orthopedic and traumatic diseases attacking at specific time periods treated by the Shu-Stream points,and explain the theory‘select Shu-Stream points for condition that alleviate or aggrav...