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CELL-FREE: 作品数：148被引量：425H指数：12; 导出分析报告; 相关作者：冉静学孙强李秀军郭晓东侯朝晖更多>>; 相关机构：哈尔滨工业大学中国航天科工集团第四研究院北京机电工程总体设计部中央民族大学凯迪迪爱通信技术有限公司更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划北京市自然科学基金更多>>

Use of priming strategies to advance the clinical application of mesenchymal stromal/stem cell-based therapy: 《World Journal of Stem Cells》2024年第1期7-18,共12页Vitale Miceli; Mesenchymal stromal/stem cells(MSCs)have garnered significant attention in the field of regenerative medicine due to their remarkable therapeutic potential.MSCs play a pivotal role in maintaining tissue homeostasis an...; 关键词：Mesenchymal stromal/stem cells Therapeutic properties Paracrine effects Cell priming Cell-free therapies Regenerative medicine

Human pluripotent stem cell-derived extracellular vesicles:From now to the future: 《World Journal of Stem Cells》2023年第5期453-465,共13页Bruno Moises de Matos Marco Augusto Stimamiglio Alejandro Correa Anny Waloski Robert; Extracellular vesicles(EVs)are nanometric particles that enclose cell-derived bioactive molecules in a lipid bilayer and serve as intercellular communication tools.Accordingly,in various biological contexts,EVs are re...; 关键词：Pluripotent stem cells Extracellular vesicles EXOSOME Cell-free therapy

Chronic wounds:pathological characteristics and their stem cell-based therapies被引量：2: 《Engineered Regeneration》2023年第1期81-94,共14页Xiangyi Wu Haofang Zhu Ye Xu Bin Kong Qian Tan; supported by grants from the National Natural Science Foundation of China (No.81974288);the National Natural Science Foundation of China (No.82101184);Shenzhen Fundamental Research Program (No.JCYJ20210324102809024);Shenzhen PhD Start-up Program (No.RCBS20210609103713045).; Chronic wounds are characterized by prolonged healing processes and poor prognoses,which have substantially impacted human health and daily life.Traditional treatment strategies have various limitations and drawbacks....; 关键词：Chronic wounds Stem cell Cell scaffold Cell-free therapy Gene modification

Adjusting the stiffness of a cell-free hydrogel system based on tissue-specific extracellular matrix to optimize adipose tissue regeneration: 《Burns & Trauma》2023年第1期217-228,共12页Ye Li Xin Bi Mengfan Wu Xinyao Chen Weiqing Zhan Ziqing Dong Feng Lu; supported by the following organizations:National Nature Science Foundation of China(81601702,81671931,81772101,81701920,81801933,81801932,81871573,81901976,81901975,81971852,8207081184,82002052);Natural Science Foundation of Guangdong Province of China(2021A1515011623);Medical Scientific Research Foundation of Guangdong Province of China(A2020542);Science and Technology Program of Guangzhou of China(201604020007);Fundamental and applied fundamental Research Regional United Fund of Guangdong Province(2019A1515110112);Administrator Foundation of Nanfang Hospital(2019B021,2020Z004);the National Undergraduate Innovation and Entrepreneurship Training Program(X202012121222,X202012121312).; Background:Large-area soft tissue defects are challenging to reconstruct.Clinical treatment methods are hampered by problems associated with injury to the donor site and the requirement for multiple surgical procedure...; 关键词：STIFFNESS Extracellular matrix Adipose tissue REGENERATION Adipose-derived stem cells Hydrogel STIFFNESS

Mesenchymal stem cells and cell-free preparations for treating atopic dermatitis: 《BIOCELL》2022年第11期2363-2367,共5页TRINIDAD MONTERO-VILCHEZ MANUEL SANCHEZ-DIAZ CAROLINA MONTERO-VILCHEZ ALVARO SIERRA-SANCHEZ SALVADOR ARIAS-SANTIAGO; Atopic dermatitis(AD)is a chronic cutaneous inflammatory disease caused by an interaction between genetic,immune and epidermal barrier factors.Several treatments can be used to treat this disease but there are patient...; 关键词：Atopic dermatitis Conditioned medium DERMATOLOGY Mesenchymal stem cells Stem cells

MSCs derived extracellular vesicles as a therapeutic paragon for neurodegenerative disorders:A viewpoint: 《BIOCELL》2022年第6期1435-1438,共4页YASHVI SHARMA SHARDA RAY SUJATA MOHANTY; Neurodegenerative disorders are a vicious woe to the public health and wellness.Uncertainty in their underlying causes,lack of effective biomarkers for their early detection,existence of only supportive therapy,and th...; 关键词：Mesenchymal stem cells Extracellular vesicles Neurodegenerative disorders Cell-free therapy REGENERATION

Mesenchymal stem cells derived secretome as an innovative cell-free therapeutic approach: 《BIOCELL》2022年第4期907-911,共5页EJLAL ABU-EL-RUB RAMADA R.KHASAWNEH FATIMAH A.ALMAHASNEH HANA M.ZEGALLAI; The paracrine and immunomodulatory cytokines secreted by mesenchymal stem cells(MSCs),generally referred to as the MSCs derived secretome,has substantial potential for the treatment of many chronic and degenerative di...; 关键词：Mesencyhmal stem cells SECRETOME Immuno-modulation CYTOKINES Growth factors

Textile-embedded Cell-free Biosensors: 《Chinese Journal of Biomedical Engineering(English Edition)》2022年第1期39-39,共1页; Freeze-dried genetic circuits can be integrated with textiles for the detection-colorimetric,or via fluorescence or luminescence-of small molecules and nucleic acids from pathogens.The authors used silicone elastomers...; 关键词：DRIED CELLULOSE free

3D bioactive cell-free-scaffolds for in-vitro/in-vivo capture and directed osteoinduction of stem cells for bone tissue regeneration被引量：13: 《Bioactive Materials》2021年第11期4083-4095,共13页Mamatali Rahman Xue-Liang Peng Xiao-Hong Zhao Hai-Lun Gong Xiao-Dan Sun Qiong Wu Dai-Xu Wei; Grants from National Natural Science Foundation of China(Grant Nos.31900950,31670991 and 52072210);National Key Research and Development Project of China(Grant No.2018YFA0900100).; Hydrophilic bone morphogenetic protein 2(BMP2)is easily degraded and difficult to load onto hydrophobic carrier materials,which limits the application of polyester materials in bone tissue engineering.Based on soybean...; 关键词：Soybean lecithin Bioactive material Cell-free scaffold BMP2 Cell-capture OSSIFICATION

Mesenchymal stem cells secretome:The cornerstone of cell-free regenerative medicine被引量：7: 《World Journal of Stem Cells》2020年第12期1529-1552,共24页Alberto González-González Daniel García-Sánchez Monica Dotta JoséC Rodríguez-Rey Flor M Pérez-Campo; Supported by Spanish Ministerio de Economía y competitividad,No.RTI2018-097324;Predoctoral program in Biomedicine from the University of Cantabria and the Instituto de Investigación Valdecilla(IDIVAL),No.PREVAL 19/02 and PREVAL 20/01.; Mesenchymal stem cells(MSCs)are the most frequently used stem cells in clinical trials due to their easy isolation from various adult tissues,their ability of homing to injury sites and their potential to differentiat...; 关键词：Mesenchymal stem cells SECRETOME Soluble factors Extra-cellular vesicles EXOSOMES Bone regeneration

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