ENDOTOXIN

作品数：255被引量：1096H指数：16
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相关作者：李兰娟马伟杭吴仲文陈亚岗俞云松更多>>
相关机构：浙江大学医学院附属第一医院复旦大学南京大学大连医科大学更多>>
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相关基金：国家自然科学基金国家重点基础研究发展计划北京市自然科学基金高等学校学科创新引智计划更多>>
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Decreased hepatic peroxisome proliferator-activated receptor-γ contributes to increased sensitivity to endotoxin in obstructive jaundice被引量：5
《World Journal of Gastroenterology》2011年第48期5267-5273,共7页Xin Lv Jian-Gang Song Hong-Hai Li Jun-Ping Ao Ping Zhang Ye-Sheng Li Shao-Li Song Xiang-Rui Wang 
Supported by China Postdoctoral Science Foundation, No.20080440626;National Natural Science Foundation of China,No. 30700788 and No. 81001545;Shanghai Leading Academic Discipline Project, No. S30203
AIM: To investigate the role of hepatic peroxisome proliferator-activated receptor-γ (PPAR-γ) in increased susceptibility to endotoxin-induced toxicity in rats with bile duct ligation during endotoxemia.METHODS: Mal...
关键词：Obstructive jaundice ENDOTOXEMIA Liver Peroxisome proliferator-activated receptor-γ ROSIGLITAZONE 
Downregulation effects of beta-elemene on the levels of plasma endotoxin,serum TNF-alpha,and hepatic CD14 expression in rats with liver fibrosis被引量：3
《Frontiers of Medicine》2011年第1期101-105,共5页Jianguo LIU Zhe ZHANG Jiechang GAO Jiwen XIE Lin YANG Shenjun HU 
It has been demonstrated thatβ-elemene could protect against carbon tetrachloride(CCl_(4))-induced liver fibrosis in our laboratory work,and the aim of this paper is to reveal the protective mechanisms ofβ-elemene.T...
关键词：liver fibrosis beta-elemene ENDOTOXIN CD14 
The relationship between activation of TLR4 and partial hepatic ischemia/reperfusion injury in mice被引量：7
《Hepatobiliary & Pancreatic Diseases International》2006年第1期101-104,共4页
This work was supported by a grant from the National Natural Science Foundation of China (No. 30200272).
BACKGROUND: Toil-like receptors (TLRs) are a group of evolutionarily conserved pattern recognition receptors involved in the activation of the immune system in response to various pathogens. In this study, we elucidat...
关键词：liver REPERFUSION INJURY TOLL-LIKE RECEPTOR ENDOTOXIN 
Effects of Salvia miltiorrhiza on intestinal microflora in rats with ischemia/reperfusion liver injury被引量：14
《Hepatobiliary & Pancreatic Diseases International》2005年第2期274-280,共7页Hui-Chun Xing, Lan-Juan Li, Kai-Jin Xu, Tian Shen, Yun-Bo Chen, Yu Chen, Su-Zhen Fu, Ji-Fang Sheng, Chun-Lei Chen, Jian-Guo Wang, Dong Yan, Fang-Wei Dai and Xiao-Ying Sha Hangzhou, China Key Laboratory of Infectious Diseases, Ministry of Public Health of China, and Institute of Infectious Diseases, Department of Infectious Diseases, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China  Zhejiang Academy of Medical Sciences, Hangzhou 310012, China 
This study was supported by grants from the NationalBasic Research Program (973) of China ( No. 2003CB515506),Postdoctoral Fund of China (20040350233), and Research Grantawarded by the First Affiliated Hospital, Zhejiang UniversitySchool of Medicine, Hangzhou, China.
BACKGROUND: Hepatic ischemia/reperfusion injury may induce intestinal microflora imbalance. Salvia miltiorrhiza is effective in promoting blood circulation and counteracting peroxidation in tissues. The aim of the pre...
关键词：Salviae miltiorrhiza hepatic ischemia/reperfusion MICROFLORA ENDOTOXIN bacterial translocation 
TLR2 mRNA Upregulation in Ischemic Lobes in Mouse Partial Hepatic Ischemia/Reperfusion Injury Model被引量：5
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2004年第2期144-146,共3页张进祥 吴河水 王琳 张锦辉 王慧 郑启昌 
ThisprojectwassupportedbyagrantfromNationalNaturalSciencesFoundationofChina (No .30 2 0 0 2 72 )
To investigate TLR2 (Toll-like receptor 2) mRNA expression in ischemic hepatic lobes under the condition of partial hepatic ischemia/reperfusion injury in BALB/c mice and its relationship with liver function impairmen...
关键词：toll-like receptor 2 reperfusion injury ENDOTOXIN liver 
Toll-like receptor 4 involvement in hepatic ischemia/reperfusion injury in mice被引量：10
《Hepatobiliary & Pancreatic Diseases International》2004年第2期250-253,共4页Ori Rotstein 
BACKGROUND: Toll-like receptor 4 (TLR4) is involved in innate immunity by recognizing endotoxin resulting in a burst of inflammatory cascade. We investigated the relation between activation of TLR4 and liver injury in...
关键词：LIVER ISCHEMIA/REPERFUSION INJURY toll-like receptor ENDOTOXIN 
Effects of endotoxin on endothelin receptor in hepatic and intestinal tissues after endotoxemia in rats被引量：12
《World Journal of Gastroenterology》2000年第2期298-300,共3页Bao Hua Liu Hui Sun Chen Ji Hong Zhou Nan Xiao 
INTRODUCTIONEndothelins(ETs) has a potent and sustainedvasoconstrictive effect on a variety of blood vessels.The vascular smooth muscle cell (VSMC)is thetarget for ETs.VSMC of the whole body containsendothelin recepto...
关键词：ENDOTOXIN ENDOTHELIN receptor liver INTESTINES RATS 
The Effects of Human Fetal Liver Cells on Experimental Fulminant Hepatic Failure in Rats
《Journal of Medical Colleges of PLA(China)》1990年第3期246-250,共5页郝飞 向居正 李奇芬 余曼英 
The beneficial dffects of human fetal liver cells on the D-galactosamine-inducedfulminant hepatic failure were observed in rats and the mechanisms of the effects investi-gated.The survival rate of the rats intraperito...
关键词：liver diseases GALACTOSAMINE CYTOSOL MALONDIALDEHYDE ENDOTOXIN HEPATIC failure ~3H-thymidine 
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