云南高校图书馆联盟文献共享服务平台- ARTESUNATE

ARTESUNATE: 作品数：73被引量：225H指数：8; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：姚丽谢红靳秋月陈立军王静更多>>; 相关机构：武警医学院太原市第三人民医院山西医科大学山西省肿瘤医院更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金广东省自然科学基金广西壮族自治区自然科学基金中国博士后科学基金更多>>

NUMB endocytic adaptor protein(NUMB)mediates the anti-hepatic fibrosis effect of artesunate(ART)by inducing senescence in hepatic stellate cells(HSCs): 《Chinese Journal of Natural Medicines》2025年第3期322-333,共12页Yangling Qiu Yujia Li Mengran Li Yingqian Wang Min Shen Jiangjuan Shao Feng Zhang Xuefen Xu Feixia Wang Zili Zhang Shizhong Zheng; supported by the National Natural Science Foundation of China(Nos.82474164,82374124,82073914,82173874,82274185,82305046 and 82304902);the Natural Science Foundation of Jiangsu Province(Nos.BK20230458 and BK20220467);the General Project of the Natural Science Research of Jiangsu Higher Education Institutions(No.23KJB310017);Young Elite Scientists Sponsorship Program by CACM(No.2022-QNRC2-B15).; Developing and identifying effective medications and targets for treating hepatic fibrosis is an urgent priority.Our previous research demonstrated the efficacy of artesunate(ART)in alleviating liver fibrosis by elimi...; 关键词：Hepatic stellate cells NUMB endocytic adaptor protein SENESCENCE ARTESUNATE UBIQUITYLATION Liver fibrosis

A self-assembled nanomicelle-based "one stone for two birds" strategy for precision therapy of hepatic ischemia-reperfusion injury: 《Nano Research》2025年第2期627-640,共14页Mengyuan Yu Jiongjie Yu Yujie Zhou Zhi Liang Hong Tang Changbiao Li Qingyang Que Hangxiang Wang Haiyang Xie Xiao Xu; This research gained support from the National Key Research and Development Program of China(No.2021YFA1100500);the Major Research Plan of the National Natural Science Foundation of China(No.92159202);the National Natural Science Foundation of China(Nos.32171368 and 81930016);State Key Laboratory for Diagnosis and Treatment of Infectious Diseases(No.zz202310);the Non profit Central Research Institute Fund of Chinese Academy of Medical Sciences(No.2023-PT320-02);the International Science and Technology Cooperation Project of Zhejiang province.; Hepatic ischemia-reperfusion injury(IRI)is an intricate and inevitable physiological event occurred in the liver transplantation(LT)and it is of paramount importance to devise novel and efficient methods to ameliorate...; 关键词：carvacrol(CAR) artesunate(ART) nanoparticles ischemia-reperfusion injury(IRI) ferroptosis

Artesunate Induces Ferroptosis in Hepatic Stellate Cells and Alleviates Liver Fibrosis via the ROCK1/ATF3 Axis: 《Journal of Clinical and Translational Hepatology》2024年第1期36-51,共16页Yingqian Wang Yujia Li Yangling Qiu Min Shen Ling Wang Jiangjuan Shao Feng Zhang Xuefen Xu Zili Zhang Mei Guo Shizhong Zheng; supported by the National Natural Science Foundation of China(No.82000572,82073914,82173874,82274185);the Natural Science Foundation of Jiangsu Province(No.BK20220467,BK20200840);the Major Project of the Natural Science Research of Jiangsu Higher Education Institutions(No.22KJB310013,19KJA310005);the Joint Project of Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica and Yangtze River Pharmaceutical(No.JKLPSE202005);the Natural Science Foundation of Nanjing University of Chinese Medicine(No.NZY82000572);Nanjing Pharmaceutical Association-Changzhou Fourth Pharmaceutical Hospital Pharmaceutical Research Fund(NO.2021YX030);Postgraduate Research&Practice Innovation Program of Jiangsu Province(No.SJCX22_0792).; Background and Aims:Development of fibrosis in chronic liver disease requires activation of hepatic stellate cells(HSCs)and leads to a poor outcome.Artesunate(Art)is an ester derivative of artemisinin that can induce ...; 关键词：Ferroptosis Liver fibrosis Antioxidant system ATF3 ROCK1

Research progress of artesunate in diabetes and its complications: 《Traditional Medicine Research》2023年第5期44-51,共8页Yuan-Hui Guo Lu-Lu Chen Ying LI Jia-Jia Duan Chuan-Xin Liu Hong-Wei Jiang; Diabetes is a metabolic disease characterized by abnormally elevated blood glucose levels.Persistent hyperglycemia leads to diabetic nephropathy,diabetic retinopathy,diabetes with periodontal disease and other diabeti...; 关键词：ARTESUNATE DIABETES diabetic complications islet cells glycolipid metabolism ANTI-INFLAMMATORY IMMUNOREGULATION

Clinical Efficacy of Artemether-Lumefantrine Artesunate-Amodiaquine of Children from Three Chadian Provinces with Acute of Uncomplicated Falciparum malariae from 6 Months to 5 Years: 《Advances in Infectious Diseases》2022年第4期788-798,共11页Issa Ramat Adam Nack Jacques Hamit Mahamat Alio Akono Ntonga Patrick Abakar Idriss Lawane Mahamat Ali Bolti; Introduction: Artemisinin-based combination therapies are the first-line antimalarial drugs used to treat uncomplicated Plasmodium falciparum malaria in many endemic countries worldwide. In Chad, since the adoption of...; 关键词：Plasmodium falciparum Artemeter-Lumefantrine Artesunate-Amodiaquine Efficacy Parasitological Density Hemoglobin Levels

Artesunate对克罗恩病样结肠炎的保护性作用及机制: 《齐齐哈尔医学院学报》2019年第8期925-928,共4页席进朱玉可吴华涛周杰王研葛思堂左芦根; 蚌埠医学院自然科学重点项目(BYKY1836ZD); 目的探讨青蒿琥酯(Artesunate)对TNBS结肠炎小鼠的治疗作用及机制。方法采用6～8周龄Balb/c小鼠,建立TNBS模型后将16只小鼠随机分为Artesunate组及Model组两组,每组8只。Artesunate组小鼠每日腹腔注射Artesunate(150 mg/kg/d),Model组...; 关键词：青蒿琥酯克罗恩病黏膜免疫肠屏障功能肠炎

Anti-inflammatory and antipyretic activities of artesunate in experimental animals: 《Journal of Coastal Life Medicine》2016年第9期737-741,共5页Ette Ettebong Emmanuel Etuk Imaobong Sunday; Supported by Education Trust Fund of the University of Uyo(Grant No.ETF 057).; Objective:To evaluate the anti-inflammatory and antipyretic potentials of artesunate in albino mice and Wistar rats respectively.Methods:For the anti-inflammatory activity,artesunate(5 mg/kg)was administered orally ag...; 关键词：ARTESUNATE ANTI-INFLAMMATORY ANTIPYRETIC IBUPROFEN

Preliminary Study on Counterfeiting of Artemether and Artesunate Marketed in Lubumbashi被引量：1: 《Pharmacology & Pharmacy》2016年第5期185-192,共8页Pierrot Mwamba Tshilumba Elie Rongorongo Kagoha Valentin Bashige Chiribagula Glauber Mbayo Kalubandika Vianney Ntabaza Ndage Trésor Sumbu Nzuzi Evodie Numbi Wa Ilunga Pierre Duez Jean Baptiste Kalonji Ndoumba; Pharmaceutical counterfeiting is a health scourge responsible for several cases of morbidity and mortality. Counterfeit medicines cause therapeutic failure, emergence of resistance in the treatment of infections. This...; 关键词：COUNTERFEIT MEDICINES ANTIMALARIAL Lubumbashi DR Congo

Protective effects of artesunate on septic lung injury in mice via modulation of heme oxygenase-1: 《China Medical Abstracts(Internal Medicine)》2016年第1期37-38,共2页曹天辉; Objective To investigate the effects of artesunate(AS)on septic lung injury in mice and to study the modulation of heme oxygenase-1(HO-1)in lung in order to clarify the mechanism of AS action.Methods Sixty Kunming mal...; 关键词：ARTESUNATE SEPTIC OXYGENASE clarify Kunming protective EDEMA saline puncture LIGATION

Antimalarial drug artesunate affords protection against carrageenan induced acute inflammation in rat: 《BIOCELL》2014年第1期1-5,共5页Vijay L.KUMAR B.GURUPRASAD Priyanka CHAUDHARY; research grant(A-059)from All India Institute of Medical Sciences,New Delhi.Artesunate and diclofenac were kind gifts from Arbro Pharmaceuticals Ltd.,New Delhi.; Artesunate, an antimalarial drug, has been shown to inhibit the release of inflammatory mediators in various disease conditions. The present study was carried out to evaluate the anti-edematogenic effect of arte- suna...; 关键词：ARTESUNATE EDEMA MYELOPEROXIDASE TNF-α PGE_(2)

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