EPITOPES

作品数：96被引量：141H指数：7
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Flu Universal Vaccines: New Tricks on an Old Virus被引量：1
《Virologica Sinica》2021年第1期13-24,共12页Ruikun Du Qinghua Cui Lijun Rong 
supported by The Drug Innovation Major Project(Grant No.2018ZX09711001);the Key Research and Development Projects of Science and Technology Department of Shandong Province(Grant No.2017CXGC1309);Shandong Provincial Natural Science Foundation of China(Grant No.ZR2019MH078,ZR2017MH086)
Conventional influenza vaccines are based on predicting the circulating viruses year by year,conferring limited effectiveness since the antigenicity of vaccine strains does not always match the circulating viruses.Thi...
关键词：Influenza virus Universal vaccine Conserved epitopes Broadly protection 
Human Monoclonal Antibodies: On the Menu of Targeted Therapeutics Against COVID-19被引量：1
《Virologica Sinica》2020年第6期713-724,共12页Junsen Chen Rui Huang Yiwen Nie Xinyue Wen Ying Wu 
supported by Grants from the National Science and Technology Major Project (Grant No.2018ZX10733403)。
Coronavirus disease 2019(COVID-19), reminiscent of the severe acute respiratory syndrome(SARS) outbreak in 2003,has been a tragic disaster to people all over the world. As there is no specific drug for COVID-19, neutr...
关键词：COVID-19 MABS S glycoprotein EPITOPES 
Localization Analysis of Heterophilic Antigen Epitopes of H1N1 Influenza Virus Hemagglutinin被引量：1
《Virologica Sinica》2019年第3期306-314,共9页Chun-Yan Guo Hai-Xiang Zhang Jun-Jun Zhang Li-Jun Sun Hui-Jin Li Dao-Yan Liang Qing Feng Yan Li Yang-Meng Feng Xin Xie Jun Hu 
supported by The National Key Research and Development Program of China (Grant No. 2016YFD0500700);The Natural Science Basic Research Program of Shaanxi Province (Grant No. 2016JM8065);Shaanxi Provincial People’s Hospital Incubation Fund Program (Grant No. 2015YX-4)
Previous studies have indicated that two monoclonal antibodies(mAbs;A1-10 and H1-84)of the hemagglutinin(HA)antigen on the H1N1 influenza virus cross-react with human brain tissue.It has been proposed that there are h...
关键词：H1N1 influenza virus HA ANTIGEN MONOCLONAL antibody LOCALIZATION Heterophilic EPITOPE 
Human leukemia antigen-A0201-restricted epitopes of humanendogenous retrovirus W family envelope(HERV-W env)inducestrong cytotoxic T lymphocyte responses被引量：4
《Virologica Sinica》2017年第4期280-289,共10页Xiaoning Tu Shan Li Lijuan Zhao Ran Xiao Xiuling Wang Fan Zhu 
supported by grants from the National Natural Sciences Foundation of China(no.31470264,no.81271820,no.30870789 and no.30300117);the Key Program of the Natural Science Foundation of Hubei Province of China(no.2014CFA078);the Stanley Foundation from the Stanley Medical Research Institute(SMRI),USA(no.06R-1366),for Dr.F Zhu;the Scientific Innovation Team Project of Hubei Province of China(no.2015CFA009)
Human endogenous retrovirus W family(HERV-W) envelope(env) has been reported to be related to several human diseases, including autoimmune disorders, and it could activate innate immunity.However, there are no reports...
关键词：HUMAN endogenous RETROVIRUS W (HERV-W) ENV peptide HLA CTL 
Identification of the Epitopes of Monoclonal Antibodies against P74 of Helicoverpa armigera Nucleopolyhedrovirus
《Virologica Sinica》2013年第6期360-367,共8页Limin Liao Dianhai Hou Huachao Huang Manli Wang Fei Deng Hualin Wang Zhihong Hu Tao Zhang 
supported by the National Science Foundation of China(31130058 to Z.H.).Monoclonal Antibodies against HearNPV P74
P74 is a per os infectivity factor of baculovirus.Here,we report the production of three monoclonal antibodies (mAbs),denoted as 20D9,20F9 and 21E1,raised against P74 of Helicoverpa armigera nucleopolyhedrovirus (Hear...
关键词：HEARNPV P74 Linear epitope Monoclonal antibody 
Advances of Bioinformatics Tools Applied in Virus Epitopes Prediction被引量：7
《Virologica Sinica》2011年第1期1-7,共7页Simon Rayner 
The National Natural Science Foundations of China (30870131);the National Key Projects in the Infectious Fields (2008ZX10002-011, 2008ZX10004-004)
In recent years,the in silico epitopes prediction tools have facilitated the progress of vaccines development significantly and many have been applied to predict epitopes in viruses successfully. Herein,a general over...
关键词：EPITOPE BIOINFORMATICS Epitope prediction algorithms 
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