POSTCONDITIONING

作品数：38被引量：305H指数：10
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相关领域：医药卫生更多>>
相关作者：薛枫蒋文平李勋韩莲花蒋廷波更多>>
相关机构：苏州大学哈尔滨医科大学天津市第三中心医院首都医科大学更多>>
相关期刊：《中国急救医学》《Chinese Journal of Traumatology》《Acta Pharmacologica Sinica》《中国现代医学杂志》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划湖北省自然科学基金山西省自然科学基金更多>>
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Pim-1 Kinase Regulating Dynamics Related Protein 1 Mediates Sevoflurane Postconditioning-induced Cardioprotection被引量：7
《Chinese Medical Journal》2017年第3期309-317,共9页Jin-Dong Liu Hui-Juan Chen Da-Liang Wang Hui Wang Qian Deng 
Background： It is well documented that sevoflurane postconditioning （SP） has a significant myocardial protection effect. However, the mechanisms underlying SP are still unclear. In the present study, we investigate...
关键词：CARDIOPROTECTION Ischemia-reperfusion Injury MITOCHONDRIA PIM-1 POSTCONDITIONING SEVOFLURANE 
Restoration of autophagic flux in myocardial tissues is required for cardioprotection of sevoflurane postconditioning in rats被引量：27
《Acta Pharmacologica Sinica》2014年第6期758-769,共12页Yu-lin ZHANG 
Acknowledgements This work was supported by the National Natural Science Foundation of China （Grant No 81070098 and 81200109）.
Aim： Sevoflurane postconditioning （SpostC） has been shown to protect the heart from ischemia-reperfusion （I/R） injury. In this study, we examined whether SpostC affected autophagic flux in myocardial tissues tha...
关键词：SEVOFLURANE inhalation anesthetics POSTCONDITIONING heart ischemia-reperfusion injury CARDIOPROTECTION AUTOPHAGY CHLOROQUINE 
Sevoflurane postconditioning alleviates action potential duration shortening and L-type calcium current suppression induced by ischemia/reperfusion injury in rat epicardial myocytes被引量：13
《Chinese Medical Journal》2012年第19期3485-3491,共7页GONG Jun-song YAO Yun-tai FANG Neng-xin HUANG Jian LI Li-huan 
This work was supported by the grant Irom the National Natural Science Foundation of China （No. 81070098） and Foundation for Postgraduates＇ Innovative Research of Peking Union Medical College （No. 2010-1002-004）.
Background It has been proved that sevoflurane postconditioning （SpostC） could protect the heart against myocardial ischemia/reperfusion injury, however, there has been few research focused on the electrophysiologic...
关键词：SEVOFLURANE POSTCONDITIONING ISCHEMIA/REPERFUSION L-type calcium current 
Sevoflurane preconditioning and postconditioning attenuate apoptosis induced by ischemia-reperfusion in rat lung
《中国现代医学杂志》2011年第6期718-726,共9页Qing Li Su-pin Zhang Timo Rinne Yong-hao Yu Guo-lin Wang 
Objective To investigate the effect of sevoflurane preconditioning and postconditioning on lung ischemia-reperfusion(IR) injury and apoptosis in rat.Methods Wistar rats were randomly assigned to four groups:sham group...
关键词：ischemia-reperfusion induced injury APOPTOSIS SEVOFLURANE PRECONDITIONING POSTCONDITIONING 
Sevoflurane postconditioning reduces myocardial reperfusion injury in rat isolated hearts via activation of PI3K/Akt signaling and modulation of Bcl-2 family proteins被引量：36
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2010年第9期661-672,共12页Li-na YU Jing YU Feng-jiang ZHANG Mei-juan YANG Ting-ting DING Jun-kuan WANG Wei HE Tao FANG Gang CHEN Min YAN 
supported by the National Natural Science Foundation of China (No. 30772090);the Natural Science Foundation of Zhejiang Province (Nos. Y204141 and R2090259);the Foundation from Science and Technology Department of Zhejiang Province (No. 2007R10034);the Foundation from the Health Bureau of Zhejiang Province (No. 2007QN007),China
Sevoflurane postconditioning reduces myocardial infarct size.The objective of this study was to examine the role of the phosphatidylinositol-3-kinase(PI3K)/Akt pathway in anesthetic postconditioning and to determine w...
关键词：SEVOFLURANE POSTCONDITIONING CARDIOPROTECTION Akt Bcl-2 BAD 
Effects of sevoflurane preconditioning and postconditioning on rat myocardial stunning in ischemic reperfusion injury被引量：19
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2010年第4期267-274,共8页An-lu DAI Li-hua FAN Feng-jiang ZHANG Mei-juan YANG Jing YU Jun-kuan WANG Tao FANG Gang CHEN Li-na YU Min YAN 
Project supported by the National Natural Science Foundation of China (No. 30772090);the Natural Science Foundation of Zhejiang Province (No. Y204141);the Foundation from Science and Tech-nology Department of Zhejiang Province (No. 2007R10034);the Foundation from the Health Bureau of Zhejiang Province (No. 2007QN007), China
Ischemic preconditioning and postconditioning distinctly attenuate ventricular arrhythmia after ischemia without affecting the severity of myocardial stunning. Therefore, we report the effects of sevofiurane precondit...
关键词：Inhalation anesthetics SEVOFLURANE POSTCONDITIONING PRECONDITIONING Ischemia-reperfusion injury Myocardial stunning 
Cardioprotection of sevoflurane postconditioning by activating extracellular signal-regulated kinase 1/2 in isolated rat hearts^1被引量：41
《Acta Pharmacologica Sinica》2008年第8期931-941,共11页Hong-tao CHEN Cheng-xiang YANG Heng LI Cheng-jing ZHANG Xian-jie WEN Jun ZHOU You-ling Fan Teng HUANG Yin-ming ZENG 
Aim： The activation of extracellular signal-regulated kinase （ERK）1/2 protects against ischemic-reperfusion injury. Whether ERK1/2 mediates the cardioprotection of sevoflurane postconditioning is unknown. We tested...
关键词：SEVOFLURANE POSTCONDITIONING extracellular signal-regulated protein kinase p70S6kinase MITOCHONDRIA cytochrome c ISCHEMIA-REPERFUSION 
Postconditioning of sevoflurane and propofol is associated with mitochondrial permeability transition pore被引量：48
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2008年第2期100-108,共9页Wei HE Feng-jiang ZHANG Shao-ping WANG Gang CHEN Cong-cong CHEN Min YAN 
Project supported by the National Natural Science Foundation ofChina (No. 30772090);the Natural Science Foundation of ZhejiangProvince (No. Y204141);the Foundation from Science and Technology Department of Zhejiang Province (No. 2007R10034);theFoundation from Personnel Department of Zhejiang Province (NoJ20050046);the Foundation from Health Department of ZhejiangProvince (No. 2007QN007), China
Background: Sevoflurane and propofol are effective cardioprotective anaesthetic agents, though the cardioprotection of propofol has not been shown in humans. Their roles and underlying mechanisms in anesthetic postcon...
关键词：SEVOFLURANE PROPOFOL POSTCONDITIONING Reperfusion injury Mitochondrial permeability transition pore （MPTP） 
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