云南高校图书馆联盟文献共享服务平台- PYRROLIZIDINE

PYRROLIZIDINE: 作品数：10被引量：60H指数：3; 导出分析报告; 相关领域：医药卫生理学更多>>; 相关作者：徐风倪轶轲刘铸晋陆仁荣更多>>; 相关机构：中国科学院更多>>; 相关期刊：《Advances in Microbiology》《Chinese Journal of Structural Chemistry》《Chinese Journal of Natural Medicines》《Acta Pharmacologica Sinica》更多>>; 相关基金：国家自然科学基金上海市青年科技启明星计划更多>>

Antitumor activity of nervosine Ⅶ,and the crosstalk between apoptosis and autophagy in HCT116 human colorectal cancer cells被引量：1: 《Chinese Journal of Natural Medicines》2020年第2期81-89,共9页HUANG Shuai ZHAO Shuang-Mei SHAN Lian-Hai ZHOU Xian-Li; This work was supported by the National Natural Science Foundation of China(No.81402803).; Nervosine Ⅶ is one of the known saturated pyrrolizidine alkaloids isolated from the plant of Liparis nervosa.This is first study to investigate the antitumor activity of nervosine Ⅶ in vitro,and the results indicate...; 关键词：Liparis nervosa PYRROLIZIDINE ALKALOIDS NervosineⅦ AUTOPHAGY APOPTOSIS HCT116 cells

Pyrrolizidine alkaloids-induced hepatic sinusoidal obstruction syndrome: Pathogenesis, clinical manifestations, diagnosis,treatment, and outcomes被引量：36: 《World Journal of Gastroenterology》2019年第28期3753-3763,共11页Xiao-Qian Yang Jin Ye Xin Li Qian Li Yu-Hu Song; Supported by National Natural Science Foundation of China,No.81570555 and No.81770582; Hepatic sinusoidal obstruction syndrome (HSOS) can be caused by the intake of pyrrolizidine alkaloids (PAs). To date, PAs-induced HSOS has not been extensively studied. In view of the difference in etiology of HSOS be...; 关键词：HEPATIC sinusoidal obstruction syndrome PYRROLIZIDINE alkaloids HEPATIC sinusoidal endothelial cells Pyrrole-protein ADDUCTS Diagnostic criteria Symptomatic TREATMENT ANTICOAGULANT therapy

Gynura Rhizoma containing pyrrolizidine alkaloids induces the hepatic sinusoidal obstruction syndrome in mice via upregulating fibrosis-related factors被引量：12: 《Acta Pharmacologica Sinica》2019年第6期781-789,共9页Fang Zhang Yue Zhou Xiao Yang Ai-zhen Xiong Zheng-tao Wang Li Yang; National Natural Science Foundation (81222053 to Dr. LY and 81603384 to Dr. A-zX);Shanghai Nature Science Foundation (16ZR1434200 to Dr. A-zX);Shanghai Rising-Star Program (17QA1403600 to Dr. A-zX);Program for Shanghai S&T Achievements Transformation and Industrialization Project (17DZ1920100 to Dr. LY);Program of Shanghai Academic/Technology Research Leader (17XD1403500 to Dr. LY).; Recently, hepatic sinusoidal obstruction syndrome (HSOS) caused by herbal preparations containing pyrrolizidine alkaloids (PAs), such as Gynura Rhizoma (Tusanqi), has gained global attention. However, the lack of a re...; 关键词：hepatic sinusoidal obstruction syndrome herbal-induced LIVER injury PYRROLIZIDINE ALKALOID Gynura Rhizoma LIVER FIBROSIS inflammation

Mitochondrial dysfunction as a mechanism of drug-induced hepatotoxicity:current understanding and future perspectives被引量：10: 《Journal of Clinical & Translational Research》2018年第1期75-100,共26页Anup Ramachandran Luqi Duan Jephte Y.Akakpo Hartmut Jaeschke; Mitochondria are critical cellular organelles for energy generation and are now also recognized as playing important roles in cellular signaling.Their central role in energy metabolism,as well as their high abundance ...; 关键词：ACETAMINOPHEN DICLOFENAC RIFAMPIN ISONIAZID valproic acid herbal SUPPLEMENTS PYRROLIZIDINE alkaloids mitochondria

Butterflies Extracts Show Antibacterial Activity: 《Advances in Microbiology》2017年第6期467-479,共13页Reuven Rasooly Miriam Rothschild Yael Gov Paul Wolferstan Robert Nash Paula Do Naomi Balaban; Extracts of several British butterfly species were tested and shown to possess powerful bactericidal activity against gram-positive bacteria (tested on Staphylococcus aureus and Bacillus anthracis). The active compoun...; 关键词：PYRROLIZIDINE ALKALOIDS BRITISH Butterflies STAPHYLOCOCCUS AUREUS Antimicrobial

Novel Synthesis and Crystal Structure of 2-(4-Methylphenyl)-3-ferrocenyl-4,4-dicyanpyrrolizidine: 《Chinese Journal of Structural Chemistry》2013年第6期853-856,共4页刘鹏张玉梅张红利耿丽君; Financially supported by the Science and Technology Support Plan Project of Hebei Province (11207184D);the Fund of Hebei Provincial Higher Education Scientific Research Plan Project (No. Q2012021); A novel ferroenyl pyrrolizidine derivative containing cyano groups, 2-O-methylphenyl）-3-ferrocenyl-4,4-dicyanpyrrolizidine （C26H25FeN3, Mr = 435.34）, was synthesized in moderate yields via a facile 1.3-dipolar cycl...; 关键词：FERROCENE PYRROLIZIDINE SYNTHESIS crystal structure

Generalist <i>versus</i>Specialist Herbivores on the Invasive <i>Senecio inaequidens</i>and a Native Related Species: What Makes the Difference?: 《American Journal of Plant Sciences》2013年第2期386-394,共9页Anne-Laure Jacquemart Valérie Vanparys Pierre Meerts; We compared herbivory pressure in the native Jacobaea vulgaris (formely Senecio jacobaea) and the alien invasive S. inaequidens in sites where they co-occur in Belgium. We predicted that the alien species experiences ...; 关键词：Enemy Release Biotic Resistance INVASIVE Plant INVASIVE Success PYRROLIZIDINE Alkaloids

Two New Pyrrolizidines from Ligularia lankongensis被引量：2: 《Chinese Chemical Letters》2004年第1期68-70,共3页AiMinTAN YunSenLI HongYANG ZhengTaoWANG HongPingHE MianZHANG XiaoJiangHAO; Two new pyrrolizidines named lankongensisine A (1), B (2) were isolated from the roots of Ligularia lankongensis collected in Lijiang, Yunnan, and their structures were established by spectroscopic analysis.; 关键词：PYRROLIZIDINE Ligularia lankongensis lankongensisine A lankongensisine B.

A New Approach to the Construction of Pyrrolizidine and Indolizidine Skeleton: Enantioselective Synthesis of (1S, 7aS)-1-hydroxypyrrolizidine and (1S, 8aS)-1-hydroxyindolizidine: 《Chinese Chemical Letters》1997年第9期773-776,共4页Dong, HQ Shi, ZC Lin, GQ; A new approach to the construction of pyrrolizidine and indolizidine skeleton was described. By employing this cyclization method the synthesis of (1S. 7aS)-1-hydroxypyrrolizidine (1a) and (1S. 8aS)-1-hydroxyindolizid...

一种合成2-苄基类取代Pyrrolizidine和Pyrrolizidinone环系的新途径: 《化学学报》1988年第2期143-148,共6页刘铸晋陆仁荣徐风; 本文报道合成Pyrrolizidinone和Pyrrolizidine环系的新方法,即通过酰亚胺正离子14成环,然后经碳正离子15重排而成Pyrrolizidinone环系.采用这种方法,合成了六个新的Pyrrolizidinone及Pyrrolizidine生物碱类似物(1—6).; 关键词：正离子硅胶洗脱阳离子柱层析 Pyrrolizidinone PYRROLIZIDINE 甲氧基苯乙酸乙酯无水硫酸钠石油醚溶剂油生物碱丁烯基

PYRROLIZIDINE