云南高校图书馆联盟文献共享服务平台- RILUZOLE

RILUZOLE: 作品数：14被引量：15H指数：2; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：王玉凯程源深吕文李树合章翔更多>>; 相关机构：佛山市第一人民医院兰州大学浙江大学医学院附属第二医院浙江大学医学院附属邵逸夫医院更多>>; 相关期刊：《Chinese Journal of Integrative Medicine》《International Journal of Ophthalmology(English edition)》《中华医学信息导报》《Neural Regeneration Research》更多>>; 相关基金：国家自然科学基金更多>>

Combined Treatment with Bojungikgi-tang(Buzhong Yiqi Decoction)and Riluzole Attenuates Cell Death in TDP-43-Expressing Cells: 《Chinese Journal of Integrative Medicine》2024年第7期616-622,共7页Eun Jin Yang; Supported by the Korea Institute of Oriental Medicine(KIOM)under Grant(No.C18040)。; Objective To examine the effect of combined treatment with Bojungikgi-tang(BJIGT,Buzhong Yiqi Decoction)and riluzole(RZ)in transactive response DNA-binding protein 43(TDP-43)stress granule(SG)cells,a amyotrophic later...; 关键词：Bojungikgi-tang Buzhong Yiqi Decoction transactive response DNA-binding protein 43 AUTOPHAGY oxidative stress amyotrophic lateral sclerosis

Rethinking to riluzole mechanism of action: the molecular link among protein kinase CK1δ activity, TDP-43 phosphorylation, and amyotrophic lateral sclerosis pharmacological treatment被引量：1: 《Neural Regeneration Research》2019年第12期2083-2085,共3页Maicol Bissaro Stefano Moro; Life expectancy in industrialized and developed countries will continue to increase in the near future. Consequently, over the last years, the incidence and social impact of neurodegenerative diseases have increased, ...; 关键词：RILUZOLE mechanism LIFE future

Activation of the TRAAK two-pore domain potassium channels in rd1 mice protects photoreceptor cells from apoptosis被引量：1: 《International Journal of Ophthalmology(English edition)》2019年第8期1243-1249,共7页Lei Wang Kang-Pei Shi Han Li Hao Huang Wen-Bin Wu Chu-Sheng Cai Xiao-Tong Zhang Xiao-Bo Zhu; Supported by National Natural Science Foundation of China (No.81271012); AIM: To investigate the expression of TWIK-related arachidonic acid-stimulated K+ channel(TRAAK) in retinal degeneration mice(rd1) and further evaluate how TRAAK affect photoreceptor cell apoptosis.METHODS: The rd1 mi...; 关键词：TRAAK RILUZOLE PHOTORECEPTOR cell APOPTOSIS

Tandem pore TWIK-related potassium channels and neuroprotection被引量：5: 《Neural Regeneration Research》2019年第8期1293-1308,共16页J.Antonio Lamas Diego Fernández-Fernández; supported by grants to JAL from the Spanish Government:Secretaría de Estado de Investigación,Desarrollo e Innovación(MINECO,BFU2014-58999-P),Galician Government:Consellería de Cultura,Educación e Ordenación Universitaria,Xunta de Galicia(GPC2015/022);European Regional Development Fund(FP7-316265-BIOCAPS);supported with Fondo Europeo de Desarrollo Regional Funds; TWIK-related potassium channels (TREK) belong to a subfamily of the two-pore domain potassium channels family with three members, TREK1, TREK2 and TWIK-related arachidonic acid-activated potassium channels. The two-po...; 关键词：TREK channels TREK-1 TREK-2 TRAAK NEUROPROTECTION free FATTY acids LYSOPHOSPHOLIPIDS RILUZOLE

钠通道Na(v)1.6与缺血性脑损伤: 《中风与神经疾病杂志》2013年第6期493-496,共4页任丽王玉凯黄铭娜龙赤黄海鹰; 佛山市科技局资助项目(No.201208105); 目的通过观察大鼠缺血脑组织中Na(v)1.6表达探讨Na(v)1.6与缺血性脑损伤的关系。方法线栓法制作大鼠脑缺血模型,168只SD大鼠分为假手术组、脑缺血组和钠通道阻滞剂-riluzole、钙通道阻滞剂-ni-modipine治疗组。大鼠脑缺血后6h、1d、2d...; 关键词：脑缺血 RILUZOLE NIMODIPINE 大鼠 Na(v)1 6

An investigation of the antinociceptive effects of Riluzole in hyperal gesia models of mice: 《Journal of Nanjing Medical University》2006年第3期172-175,共4页Xiaoping Xia Zhenliang Ma Yinming Zeng; Key Laboratory Foundation of Jiangsu Province Department of Health(WK200501); Objective： To investigate the antinociceptive effects of Riluzole administered intraperitoneally in three hyperalgesia model of mice. Methods： Antinociceptive tests in C57BL mice were investigated with formalin test...; 关键词：RILUZOLE Formalin test INFLAMMATION PAIN GLUTAMATE NOCICEPTION

神经外科: 《中国医学文摘（外科学）》2005年第5期434-446,共13页; 颅脑外伤：组织化院前钻孔引流在脑疝期颅内血肿救治中的作用；Riluzole对大鼠早期创伤性脑水肿作用的实验研究；亚低温治疗重型颅脑损伤临床疗效的评价；原发性脑干损伤41例分析;急性颅脑损伤并发精神障碍76例临床分析……; 关键词：神经外科 RILUZOLE 原发性脑干损伤创伤性脑水肿重型颅脑损伤急性颅脑损伤亚低温治疗发精神障碍颅内血肿

Riluzole对大鼠早期创伤性脑水肿作用的实验研究: 《医学临床研究》2005年第6期775-777,共3页赵贤军刘运生裘明德康笃伦; 【目的】探讨电压门控Na+通道拮抗剂riluzole对大鼠早期创伤性脑水肿的作用以及可能的作用机制。【方法】20只Wistar大鼠随机分组,按照Feeney的方法制作颅脑损伤模型,治疗组于损伤后15min、6h、18h、30h分别给予riluzole尾静脉注射。按...; 关键词：脑水肿脑损伤大鼠

ELDEPRYL AND RILUZOLE INHIBIT 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE(MPTP)-INDUCED NIGRAL NEURONAL APOPTOSIS IN MICE: 《Journal of Shanghai Second Medical University(Foreign Language Edition)》2002年第1期1-6,共6页陈生弟郭明刘振国陈红专; SupportedbytheNationalProgramofBasicResearch (BrainScience ,G19990 5 40 0 8)ofChina ,thetrainingprogramfortheChineseMinistryofEducationspecialfortheReturnScholarsfromabroad ,andthe 10 0 Cross CenturyoutstandingscholarsofacademicscienceinShanghaiHea; Objective To investigate the possible role of apoptosis in the pathogenesis of Parkinson’s disease. Methods C- 57 BL mice were treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine(MPTP), and TUNEL and flow cytom...; 关键词：Parkinson's disease apoptosis substantia nigra PC12 MPTP MPP + Eldepryl Riluzole

脊髓腹侧压迫损伤后MP、Iloprost和Riluzole对Bcl-2表达的影响被引量：1: 《中国脊柱脊髓杂志》2001年第5期282-284,共3页张峡王正国朱佩芳; 目的 :观察脊髓腹侧压迫损伤后Bcl 2表达的动态变化及神经保护剂对Bcl 2表达的影响。方法 :大鼠胸脊髓腹侧压迫损伤后 ,将受试动物分别用甲基强的松龙 (MP)、Iloprost、Riluzole及以上三种药物合用联合治疗。应用免疫组织化学及原位杂...; 关键词：脊髓损伤 BCL-2 神经保护剂

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