supported by the National Natural Science Foundation of China,No.82171521(to CL);the Special Funds ofTaishan Scholars Project of Shandong Province,No.tsqn202211368(to CL);the Natural Science Foundation of Shandong Province,Nos.ZR2022YQ65(to CL),ZR2021MH073(to CL),ZR2019PH109(to WW);the Projects of Medical and Health Technology Development Program in Shandong Province,China,Nos.202003090720(to DZ),202003070728(to JL),2019 WS329(to DW);the Scientific Research Foundation of Binzhou Medical University,No.BY2018KJ21(to DW)。
Social dysfunction is a risk factor for several neuropsychiatric illnesses.Previous studies have shown that the lateral septum(LS)-related pathway plays a critical role in mediating social behaviors.Howeve r,the role ...
supported by the National Natural Science Foundation of China,No.81760242(to MGM).
Dysregulation of hyperpolarization-activated cyclic nucleotide-gated cation(HCN)channels alters neuronal excitability.However,the role of HCN channels in status epilepticus is not fully understood.In this study,we est...
supported by scholarships from Conselho Nacional de Desenvolvimento Científico e Tecnológico(CNPq);Coordenaao de Aperfeicoamento de Pessoal de Nível Superior(CAPES),Brazil(to TCM and DR);supported by the Kungl Vetenskapssamh Scholarship(Royal Society of Arts and Scientists);provided by Uppsala University,Sweden(to TCM);supported by the Swedish Research Council and the Swedish Brain Research Foundation(to HBS)。
Mechanisms of homeostatic plasticity promote compensatory changes of cellular excitability in response to chronic changes in the network activity.This type of plasticity is essential for the maintenance of brain circu...
supported by the National Natural Science Foundation of China,No.81330029,81501057;the Natural Science Foundation of Tianjin of China,No.17JCQNJC12000;the Tianjin Medical University General Hospital Funding in China,No.ZYYFY2016014
Traumatic brain injury can cause loss of neuronal tissue, remote symptomatic epilepsy, and cognitive deficits. However, the mechanisms underlying the effects of traumatic brain injury are not yet clear. Hippocampal ex...
supported by the National Natural Sciences Foundation of China,No.61534003,61076118;the Innovation Foundation for State Key Laboratory of the Ministry of Science and Technology,China,No.2016-2018;a grant from the Open Projects of Key Laboratory of Child Development and Learning of the Ministry of Education of China,No.CDLS201205
The electrical excitability of neural networks is influenced by different environmental factors. Effective and simple methods are required to objectively and quantitatively evaluate the influence of such factors, incl...
supported by the National Natural Science Foundation of China,No.31500836,81671288;the Natural Science Foundation of Anhui Province of China,No.1608085QH176
Limited by the tiny structure of axons,the effects of these axonal hyperpolarizing inputs on neuronal activity have not been directly elucidated.Here,we imitated these processes by simultaneously recording the activit...
supported by Major State Basic Research Development Program of China(973 Program),No.2011CB504400
The hippocampal region of the brain is important for encoding environment inputs and memory formation. However, the underlying mechanisms are unclear. To investigate the behavior of indi-vidual neurons in response to ...
funded by the General Project of Medical Technology of Military during the "12~(th) Five-Year Plan"Period, No. CWS11J00
Hyperhomocysteinemia is an important risk factor for preeclampsia-eclampsia. This study established a pregnant rat model of hyperhomocysteinemia, in which blood plasma homocysteine concentrations were twice or three t...
Science and Technology Project of Shandong Province, No. 032050117
The aim of this study was to observe the changes in monoamine and amino acid neurotransmitters in the telencephalon of rats at four functional states after exhaustive exercise and treatment with a Yang-invigorating co...
Neuronal connections can be detected by neuronal network discharges in hippocampal neurons cultured on multi-electrodes.However,the multi-electrode-array(MEA)has not been widely used in hippocampal slice culture stu...