GELATIN

作品数：313被引量：563H指数：10
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Constructing a biofunctionalized 3D-printed gelatin/sodium alginate/chitosan tri-polymer complex scaffold with improvised biological andmechanical properties for bone-tissue engineering
《Bio-Design and Manufacturing》2024年第1期57-73,共17页Amit Kumar Singh Krishna Pramanik Amit Biswas 
The authors are thankful to Ministry of Human Resource Development(presently Ministry of Education),Government of India,New Delhi,for providing research facility by sanctioning Center of Excellence(F.No.5-6/2013-TS VII)in Tissue Engineering and Center of Excellence in Orthopedic Tissue Engineering and Rehabilitation funded by World Bank under TEQIP-II.
Sodium alginate(SA)/chitosan(CH)polyelectrolyte scaffold is a suitable substrate for tissue-engineering application.The present study deals with further improvement in the tensile strength and biological properties of...
关键词：SCAFFOLD Biomaterial Sodium alginate CHITOSAN GELATIN 3D printing Tissue engineering 
3D-printed engineered bacteria-laden gelatin/sodium alginate composite hydrogels for biological detection of ionizing radiation
《Bio-Design and Manufacturing》2023年第4期439-450,共12页Ziyuan Chen Jintao Shen Meng Wei Wenrui Yan Qiucheng Yan Zhangyu Li Yaqiong Chen Feng Zhang Lina Du Bochuan Yuan Yiguang Jin 
supported by the Special Program for Capability Promotion
Nuclear safety is a global growing concern,where ionizing radiation(IR)is a major injury factor resulting in serious damage to organisms.The detection of IR is usually conducted with physical dosimeters;however,biolog...
关键词：3D printing ALGINATE Engineered bacteria GELATIN HYDROGEL Ionizing radiation 
Advanced strategies in the application of gelatin-based bioink for extrusion bioprinting被引量：5
《Bio-Design and Manufacturing》2023年第5期586-608,共23页Jirong Yang Huimin He Duo Li Qian Zhang Lizhi Xu Changshun Ruan 
support for this work from the National Key R&D Program of China(No.2018YFA0703100);the National Natural Sci-ence Foundation of China(Nos.32122046,82072082,and 32000959);the Youth Innovation Promotion Association of CAS(No.2019350);the Guangdong Natural Science Foundation(No.2019A1515111197);the Shenzhen Fundamental Research Foun-dation(Nos.JCYJ20190812162809131,JCYJ20200109114006014,JCYJ20210324113001005,and JCYJ20210324115814040).
The significance of bioink suitability for the extrusion bioprinting of tissue-like constructs cannot be overemphasized.Gelatin,derived from the hydrolysis of collagen,not only can mimic the extracellular matrix to imm...
关键词：Gelatin-based bioink Extrusion bioprinting Tissue-like construct 
Alginate/gelatin/boron-doped hydroxyapatite-coated Ti implants:in vitro and in vivo evaluation of osseointegration
《Bio-Design and Manufacturing》2023年第3期217-242,共26页Ahmet E.Pazarçeviren Zafer Evis Tayfun Dikmen Korhan Altunbas Mustafa V.Yaprakçı Dilek Keskin Aysen Tezcaner 
Acknowledgements Authors would like to thank Center of Excellence in Biomaterials and Tissue Engineering(BIOMATEN)for the support provided.Authors also acknowledge financial support provided by National Boron Institute(BOREN,Grant No:2018-31-07-25-001).
In this study,boron-doped hydroxyapatite(BHT)-loaded alginate/gelatin-based(A/G)hydrogel coating on Ti was fabricated to support bone integration through triggering osteoinduction,vascularization and immunomodulation....
关键词：Boron Alginate/gelatin Implant coating Titanium Osteochondral model 
Gelatin-based hydrogel functionalized with taurinemoieties for in vivo skin tissue regeneration被引量：2
《Bio-Design and Manufacturing》2023年第3期284-297,共14页Farnaz Rahimi Nima Ahmadkhani Aida Goodarzi Fariba Noori Sajad Hassanzadeh Sepideh Saghati Mehdi Khanmohammadi Arash Goodarzi 
Functionalized hydrogels stimulate the migration and morphogenesis of endothelial cells(ECs)and are useful substrates for wound healing.The present study investigates the feasibility of covalent conjugation of taurine...
关键词：Taurine conjugation Covalent crosslinking Immobilization of growth factors Gelatin-based hydrogel Endothelial cells 
Evaluation of different crosslinking methods in altering the properties of extrusion-printed chitosan-basedmulti-material hydrogel composites被引量：3
《Bio-Design and Manufacturing》2023年第2期150-173,共24页Suihong Liu Haiguang Zhang Tilman Ahlfeld David Kilian Yakui Liu Michael Gelinsky Qingxi Hu 
The authors acknowledge the funding support from the National Natural Science Foundation of China(Nos.52175474 and 51775324);the China Scholarship Council(No.202006890054).
Three-dimensional printing technologies exhibit tremendous potential in the advancing fields of tissue engineering and regenerative medicine due to the precise spatial control over depositing the biomaterial.Despite t...
关键词：Multi-material composite hydrogel Crosslinking mechanism CHITOSAN GELATIN Egg white 3D printing 
Rapid and mass manufacturing of soft hydrogel microstructures for cell patterns assisted by 3D printing被引量：1
《Bio-Design and Manufacturing》2022年第4期641-659,共19页Chaofan He Xuechun Chen Yuan Sun Mingjun Xie Kang Yu Jing He Jinwei Lu Qing Gao Jing Nie Yi Wang Yong He 
sponsored by the National Key Research and Development Program of China (No.2018YFA0703000);the National Natural Science Foundation of China (Nos.T2121004 and U1909218);supported by the Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine (No.ZYYCXTD-D-202002)。
Micro-/nano-patterns on hydrogels are widely used in cell patterning.However,manufacturing molds with traditional lithography is time-consuming and expensive.In addition,the excessive demolding force can easily damage...
关键词：3D printing Gelatin-based hydrogel Cell pattern Cardiomyocytes beating 
Fabrication of gelatin methacryloyl hydrogel microneedles for transdermal delivery of metformin in diabetic rats被引量：8
《Bio-Design and Manufacturing》2021年第4期902-911,共10页Zhiyong Zeng Guohua Jiang Tianqi Liu Gao Song Yanfang Sun Xueya Zhang Yanting Jing Mingjia Feng Yufei Shi 
supported by the National Natural Science Foundation of China(No.51873194);the Natural Science Foundation of Zhejiang Province,China(No.LY18E030006).
Injection therapy for diabetes has poor patient compliance,and the pain occurring at the site of subcutaneous injections causes significant inconvenience to diabetic patients.In this work,to demonstrate the benefits o...
关键词：MICRONEEDLES METFORMIN Transdermal delivery BIODEGRADABLE GELATIN Hypoglycemic effect 
3D human nonalcoholic hepatic steatosis and fibrosis models被引量：5
《Bio-Design and Manufacturing》2021年第2期157-170,共14页Sushila Maharjan Diana Bonilla Princy Sindurakar Hongbin Li Wanlu Li Sergio Duarte Ali Zarrinpar Y.Shrike Zhang 
YSZ received funding from National Institutes of Health(K99CA201603,R00CA201603,R21EB025270,R21EB026175,R01EB028143,R03EB027984);National Science Foundation(1935105);Brigham Research Institute New England Anti-Vivisection Foundation,and American Fund for Alternatives to Animal Research(AFAAR).AZ received funding from National Institutes of Health(K08DK113244,R01MD012579);SD received funding from National Institutes of Health(R01MD012579-UT20664DS).
This study presents a simple and robust three-dimensional human hepatic tissue model to emulate steatotic and fibrotic conditions and provide an in vitro model for drug testing and mechanistic studies.Using a photolit...
关键词：Nonalcoholic fatty liver disease(NAFLD) Gelatin methacryloyl(GelMA) PHOTOCROSSLINKING STEATOSIS 
Gelatin-based hydrogels combined with electrical stimulation to modulate neonatal rat cardiomyocyte beating and promote maturation被引量：1
《Bio-Design and Manufacturing》2021年第1期100-110,共11页Feng Zhang Kaiyun Qu Xiaopei Li Chaoming Liu Lazarus S.Ortiz Kaihong Wu Xiaowei Wang Ningping Huang 
This work was financially supported by the National Natural Science Foundation of China(Grant No.31871017);the Natural Science Foundation of Jiangsu Province,China(Grant No.BK20171352);the Southeast University-Nanjing Medical University Cooperative research project(2242019K3DN05);the Medical Science and Technology Development Foundation,Jiangsu Provincial Commission of Health and Family Planning,China(ZDRCA2016073);the“111”Project(B17011,Ministry of Education of China).
Cardiovascular diseases are the leading cause of morbidity and mortality throughout the world underlining the importance of efficient treatments including disease modeling and drug discovery by cardiac tissue engineer...
关键词：Gelatin hydrogel Electrical stimulation Cardiomyocyte maturation Cardiac tissue engineering 
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