supported by the National Natural Science Foundation of China(52173151,82002734,51803067);the Natural Science Foundation of Guangdong Province of China(2021A1515011084,2019A1515110312);the Fundamental Research Funds for the Central Universities(22qntd1302);the Shenzhen Outbound Postdoctoral Scientific Research Fund(SZBH202108).
Cartilage tissues possess an extremely limited capacity for self-repair,and current clinical surgical approaches for treating articular cartilage defects can only provide short-term relief. Despite significantadvances...
funded by Donghua University Postgraduate Innovation and Entrepreneurship Ability Training Program(yjssc2023002);supported by Science and Technology Commission of Shanghai Municipality,China(grant numbers 20S31900900 and 20DZ2254900);Sino German Science Foundation Research Exchange Center,China(M-0263);China Education Association for International Exchange(2022181).
Physiological repair of large-sized bone defects requires instructive scaffolds with appropriate mechanical properties,biocompatibility,biodegradability,vasculogenic ability and osteo-inductivity.The objective of this...
supported by the National Natural Science Foundation of China(Grant Nos 82272472,52373146,52173131,51973108);Natural Science Foundation of Shanghai(Grant No.22ZR1424700).
Platelet-rich plasma(PRP)that has various growth factors has been used clinically in cartilage repair.However,the short residence time and release time at the injury site limit its therapeutic effect.The present study...
supported by the National Natural Science Foundation of China(82270721);the National Natural Science Foundation of China(81873600).
In recent years,there has been an increasing focus on the application of hydrogels in tissue engineering.The integration of 3D bioprinting technology has expanded the potential applications of hydrogels.However,few co...
supported by the National Natural Science Foundation of China(Grant No.52075285);the Applied Basic Research Project of Sichuan Province(Grant No.2021YJ0563).
Biopolymer microbeads present substantial benefits for cell expansion,tissue engineering,and drug release applications.However,a fabrication system capable of producing homogeneous microspheres with high precision and...
supported by the National Key Research and Development Project(grant no.2019YFD0901905).
Chronic diabetic wound healing remains a formidable challenge due to susceptibility to bacterial infection,excessive oxidative stress,and poor angiogenesis.To address these issues,a sodium alginate(SA)based phototherm...
supported by the National Natural Science Foundation of China(31870960,32171331 and 82130061);the Fundamental Research Funds for the Central Universities,Huazhong University of Science and Technology(2019kfyXMBZ021 and 2020kfyXJJS115).
Skin defect is common in daily life,but repairing large skin defects remains a challenge.Using biomaterials to deliver biochemical or physical factors to promote skin tissue regeneration is of great significance for a...
National Foundation for Liver Research(NFLR)for financially supporting the cell-based work in this project.CIBER-BBN is an initiative funded by the VI National R&D&I Plan 2008–2011,Iniciativa Ingenio 2010,Consolider Program.CIBER actions are financed by the Instituto de Salud CarlosⅢwith assistance from the European Regional Development Fund;the University Grants Commission,India for the award of the Basic Scientific Research(UGC-BSR)Faculty Fellowship[No.F.4-5(11)2019(BSR)].
The current study investigated a triad,which comprises of adipose tissue derived stem cells isolated from infrapatellar fat pad and gelatin/polyvinyl alcohol(PVA)-based matrix with exclusive ascorbic acid signalling.T...
supported by following grants:the National Key Research and Development Program of China(grant number 2017YFA0104304);the National Natural Science Foundation of China(grant numbers 81571213,82070459 to B.W.,grant numbers 81800583 to Y.Y.X.);Key Project of Jiangsu Province(grant number BE2020765 to B.W.);Nanjing Medical Science and Technique Development Foundation(grant numbers QRX17006,QRX17057,ZKX20016 to B.W.);Nanjing Medical Science and Technique Development Foundation(grant number YKK20071 to H.Y.);Jiangsu Provincial Plan for Mass Entrepreneurship and Innovation(2019,B.W.);Project of Modern Hospital Management and Development Institute,Nanjing University/Aid project of Nanjing Drum Tower Hospital Health,Education&Research Foundation(grant number NDYG2020030 to B.W.).
Accumulating research has indicated that the transplantation of combined stem cells and scaffolds is an effective method for spinal cord injury(SCI).The development of three-dimensional(3D)bioprinting technology can m...
supported by Postdoctoral Science Foundation of China(No.194012);National Natural Science Foundation of China(No.82172398);Science&Technological Convenience Foundation of Dalian(No.2020JJ27SN076);Doctoral Research Starting Foundation of Affiliated Zhongshan Hospital of Dalian University(No.DLDXZSYY-BK201809).
The ideal scaffold material of angiogenesis should have mechanical strength and provide appropriate physiological microporous structures to mimic the extracellular matrix environment.In this study,we constructed an in...