云南高校图书馆联盟文献共享服务平台- TETRAMETHYLPYRAZINE

TETRAMETHYLPYRAZINE: 作品数：58被引量：265H指数：9; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：文志斌贺石林何晓凡庄沛张婉玉更多>>; 相关机构：中南大学齐鲁工业大学天津科技大学沈阳华泰药物研究所更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金湖北省自然科学基金山东省科技发展计划项目国家高技术研究发展计划更多>>

Tetramethylpyrazine and paeoniflorin combination(TMP-PF)alleviates atherosclerosis progress by reducing hyperlipemia and inhibiting plaque angiogenesis via the NR4A1/VEGFR2 pathway: 《Food Science and Human Wellness》2024年第5期2642-2652,共11页Rong Yuan Qiqi Xin Weili Shi Yu Miao Zhengchuan Zhu Yahui Yuan Ying Chen Xiaoning Chen Sean Xiao Leng Keji Chen Weihong Cong; supported by Fundamental Research Funds for the Central Public Welfare Research Institutes(ZZ11-061,ZZ14-YQ-007);the National Natural Science Foundation of China(82004193);CACMS Innovation Fund(CI 2021A00914);Irma and Paul Milstein Program for Senior Health of Milstein Medical Asian American Partnership Foundation。; Atherosclerosis remains a great threat to human health worldwide.Previous studies found that tetramethylpyrazine(TMP)and paeonifl orin(PF)combination(TMP-PF)exerts anti-atherosclerotic effects in vitro.However,whether...; 关键词：ATHEROSCLEROSIS HYPERLIPEMIA ANGIOGENESIS Plaque stability Chinese medicine TETRAMETHYLPYRAZINE PAEONIFLORIN

Tetramethylpyrazine prevents liver fibrotic injury in mice by targeting hepatocyte-derived and mitochondrial DNA-enriched extracellular vesicles被引量：13: 《Acta Pharmacologica Sinica》2022年第8期2026-2041,共16页Ya-jing Li Run-ping Liu Ming-ning Ding Qi Zheng Jian-zhi Wu Xiao-yong Xue Yi-qing Gu Bo-ning Ma Ya-jie Cai Shuo Li Sheng Lin Lu-yong Zhang Xiaojiaoyang Li; supported by the Beijing Municipal Science&Technology Commission(Grant No.7212174 to XL);National Natural Science Foundation of China(Grant No.82004045 to XL);Beijing Nova Program of Science&Technology(Grant No.Z191100001119088 to XL,Grant No.Z201100006820025 to RL);the Young Talents Promotion Project of China Association of Traditional Chinese Medicine(Grant No.2020-QNRC2-01 to XL);Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine(Grant No.ZYYCXTD-C-202006 to XL).; Liver fibrosis is the common consequence of almost all liver diseases and has become an urgent clinical problem without efficient therapies.Recent evidence has shown that hepatocytes-derived extracellular vesicles(EVs...; 关键词：liver fibrosis TETRAMETHYLPYRAZINE CCL4 ACETAMINOPHEN extracellular vesicle intercellular communication mouse primary hepatocytes hepatic stellate cells

Tetramethylpyrazine inhibits proliferation of colon cancer cells in vitro被引量：4: 《World Journal of Clinical Cases》2021年第18期4542-4552,共11页Hua Li Yan-Xu Hou Yu Yang Qing-Qiang He Tian-Hua Gao Xiao-Feng Zhao Zhi-Bin Huo Shu-Bo Chen Deng-Xiang Liu; BACKGROUND Colon cancer is one of the most common malignancies worldwide,and chemotherapy is a widely used strategy in colon cancer clinical therapy.However,chemotherapy resistance is a major cause of disease recurren...; 关键词：TETRAMETHYLPYRAZINE Colon cancer Apoptosis Cell proliferation CHEMOTHERAPY Cell cycle

Percutaneous absorption and brain distribution facilitation of borneol on tetramethylpyrazine in a microemulsion-based transdermal therapeutic system被引量：4: 《Asian Journal of Pharmaceutical Sciences》2019年第3期305-312,共8页Xiaoge Hu Ning Cheng Jihui Zhao Xianghua Piao Yulu Yan Qibo Zhang Kuan Zhou Yongtai Zhang Nianping Feng; supported by the Program from Shanghai Uni-versity of Traditional Chinese Medicine(B201725); In this study, we show that the percutaneous absorption and brain distribution of tetramethylpyrazine(TMP) is enhanced when combined with borneol(BN) in a microemulsionbased transdermal therapeutic system(ME-TTS). The...; 关键词：TETRAMETHYLPYRAZINE BORNEOL MICROEMULSION PERCUTANEOUS absorption Brain distribution

Synergistic Effects of Chuanxiong-Chishao Herb-Pair on Promoting Angiogenesis at Network Pharmacological and Pharmacodynamic Levels被引量：20: 《Chinese Journal of Integrative Medicine》2017年第9期654-662,共9页WANG Yan GUO Gang YANG Bin-rui XIN Qi-qi LIAO Qi-wen LEE Simon Ming-Yuen HU Yuan-jia CHEN Ke-ji CONG Wei-hong; Supported by Beijing Municipal Science and Technology Commission(No.Z141100002214011);the Science and Technology Development Fund of Macao SAR(No.069/2015/A2 and 134/2014/A3);Research Committee of University of Macao(No.MYRG2015-00182-ICMS-QRCM,MYRG2015-00214-ICMS-QRCM,MYRG139(Y1-L4)-ICMS12-LMY,and MYRG2016-00129-ICMS-QRCM),China; Objective： To investigate the synergistic effects of Chuanxiong-Chishao herb-pair （CCHP） on promoting angiogenesis in silico and in vivo. Methods： The mechanisms of action of an herb-pair, Chuanxiong- Chishao, wer...; 关键词：TETRAMETHYLPYRAZINE paeoniflorin angiogenesis network pharmacology

Pharmacokinetics of Tetramethylpyrazine Hydrochloride in Rabbits Blood after Intranasal Administration被引量：1: 《Chinese Herbal Medicines》2015年第4期316-322,共7页Jin-fan Yan Feng Han Li Ma Yan-jing Cheng Jing Gao Jin-li Deng Xia Feng; National Science and Technology Major Project(No.2011ZX09102-003-05,China); Objective To study the pharmacokinetic behavior of tetramethylpyrazine hydrochloride（TMPH） in plasma of rabbits after intranasal administration and the relationship between absorption and dosage, furthermore, to ill...; 关键词：borneol intranasal administration musk pharmacokinetics tetramethylpyrazine hydrochloride

Inhibitory Effect of Tetramethylpyrazine Preconditioning on Overload Training-Induced Myocardial Apoptosis in Rats被引量：5: 《Chinese Journal of Integrative Medicine》2015年第6期423-430,共8页杨翼李章华柳华石武谛张杰; Supported by the National Natural Science Foundation of China(No.30700388);Natural Science Foundation of Hubei Province,China(No.2011CDB313); Objective： To investigate the inhibitory effect of tetramethylpyrazine （Tot） preconditioning on overload training-induced myocardial apoptosis in rats, and to explore cardioprotective mechanisms of Tot precondition...; 关键词：overload training TETRAMETHYLPYRAZINE PRECONDITIONING myocardial apoptosis

Effects of Tetramethylpyrazine on Cardiac Function and Mortality Rate in Septic Rats被引量：7: 《Chinese Journal of Integrative Medicine》2012年第8期610-615,共6页郭力恒杨澄王磊陈全福胡亚南张敏州; Supported by the Fund for Social Development Project from Department of Science and Technology,Guangdong Province, China(No.2011KT1988); Objective： To study the effects of tetramethylpyrazine （TMP） on cardiac function and mortality rate in septic rats. Methods： Fifty male Sprague-Dawley rats were randomized into a sham-operation group （sham group,...; 关键词：TETRAMETHYLPYRAZINE SEPSIS cardiac function mortality rate

Protective Effects of Tetramethylpyrazine on Glutamate-Induced Neurotoxicity in Mice被引量：1: 《Journal of Behavioral and Brain Science》2012年第3期326-332,共7页Yongping Zhang Zimo Huang Lijiang Yu Libin Zhang; The aim of this study was to investigate the potential protective effect of tetramethylpyrazine (TMP), one of available blood-activating and stasis-eliminating components from traditional Chinese medicines, on glutama...; 关键词：EXCITATORY Amino Acids NEUROTOXICITY NEUROPROTECTION TETRAMETHYLPYRAZINE NMDARs MICE

EXPERIMENTAL STUDY ON THE EFFECT OF ACUPUNCTURE ON TROPISM-DISTRIBUTION OF TETRAMETHYLPYRAZINE AND THE CONTENT OF cAMP IN ARTHRITIS RATS: 《World Journal of Acupuncture-Moxibustion》2005年第3期43-48,共6页谷雨陈以国; Objective： To verify two hypotheses： 1 ） Acupuncture can increase the re-distribution of tetramethylpyrazine （ligustrazine） hydrochloride （TMPH） to the target organs in adjuvant arthritic rats. 2） Cyclic Adeno...; 关键词：Adjuvant arthritis ACUPUNCTURE Tetramethylpyrazine hydrochloride CAMP

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