NICK

作品数:116被引量:144H指数:6
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相关领域:医药卫生更多>>
相关作者:杨松涛葛金英夏咸柱王喜军步志高更多>>
相关机构:中国农业科学院哈尔滨兽医研究所青岛大学北京协和医学院吉林农业大学更多>>
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相关基金:国家自然科学基金天津市科技计划国家科技支撑计划国家高技术研究发展计划更多>>
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利用改良的CRISPR/Cas9n double nick系统构建DPF2基因敲除的人胰腺癌PANC-1细胞株
《宁夏医科大学学报》2023年第12期1189-1193,共5页黄卫东 张文胜 陈一帆 郭嘉义 
宁夏自然科学基金项目(2018AAC03075);宁夏回族自治区重点研发计划项目(2022BEG03151)。
目的利用改良的CRISPR/Cas9n double nick系统构建DPF2基因敲除的PANC-1人胰腺癌细胞模型。方法设计两对靶向DPF2基因第四外显子上下游的单链向导RNA(single guide RNA,sgRNA),化学合成sgRNA寡核苷酸序列,并克隆至pGL3-U6-sgRNA-PGK-pur...
关键词:DPF2基因 CRISPR/Cas9n double nike系统 基因敲除 PANC-1细胞株 
Stress effect on lattice thermal conductivity of anode material NiNB_(2)O_(6)for lithium-ion batteries
《Chinese Physics B》2023年第5期43-48,共6页陈奥 童话 吴成伟 谢国锋 谢忠祥 向长青 周五星 
the National Natural Science Foundation of China(Grant Nos.12074115 and 11874145);the Natural Science Foundation of Hunan Province,China(Grant No.2021JJ30202)。
The thermal transport properties of NiNB_(2)O_(6)as anode material for lithium-ion battery and the effect of strain were studied by machine learning interatomic potential combined with Boltzmann transport equation.The...
关键词:nickel niobate lattice thermal conductivity uniaxial strain machine learning potential 
Regulatory Effects of Zuogui Pill on Apoptosis of Follicles in Rats Injured by 60Co-γRays Based on PI3K/Akt/m TOR Signaling Pathway
《Medicinal Plant》2022年第5期45-50,58,共7页Fenqin ZHAO Mingxia AN Xiaonan DING Jieying LIU Yan ZHAO Zhihui XIE Shuping LI 
Supported by National Natural Science Foundation of China(81760806);Project of Traditional Chinese Medicine Administration of Gansu Province(GZK-2019-28);Innovation Ability Improvement Project of Higher Education Institutions of Gansu Province(2019B-103)。
[Objectives]To explore the protective effects of Zuogui Pill on ^(60)Co-γ-ray-induced premature aging of rats based on phosphatidylinositol 3-kinase/protein kinase B/mammalian target of rapamycin(PI3K/Akt/mTOR)signal...
关键词:Radiation injury Premature ovarian failure(POF) Zuogui Pill Terminal deoxynucleotidyl transferase(TdT)-mediated dUTP nick-end labeling(TUNEL) Phosphatidylinositol-3-kinases/protein kinase B/mammalian target of rapamycin(PI3K/Akt/mTOR)signaling pathway B-cell lymphoma-2 Bcl-2-associated X protein 
Discovering Nick:An Analysis of the Narrative Features in The Great Gatsby
《Psychology Research》2022年第8期608-611,共4页WANG Yan 
Fitzgerald tells the story in The Great Gatsby through the dramatized narrator, or the character in the play which helps this novel become a classic one. In this paper, the endeavor is to discover Nick Carraway both a...
关键词:NICK NARRATOR narrative features 
整本书阅读:构建思维型英语阅读课堂——以Nick Nelly and Jake为例
《英语教师》2022年第6期18-22,共5页蒋元琪 
江苏省苏州市高新区教育科学“十四五”规划2021年度“重点立项”课题“基于思维品质提升的初中英语整本书阅读教学研究”(SND-2021-ZD-034)的部分研究成果。
阐述通过整本书阅读实现思维品质提升的理论依据及整本书阅读的特点与优势。以外研社《多维阅读》第13级Nick Nelly and Jake为例,探索以提升学生思维品质为目标的整本书阅读教学的实施,即观察封面展开想象,形成阅读期待;预测情节走近人...
关键词:整本书阅读 思维品质 逻辑思维 批判思维 创造思维 
从凝视理论看摇滚乐中的女性他者——以Nick Cave的《Where The Wild Roses Grow》为例
《戏剧之家》2021年第29期54-55,共2页吴梅云 
《Where The Wild Roses Grow》是澳大利亚艺术家Nick Cave所在乐队最负盛名的谋杀概念专辑《Murder Ballads》中的一首歌曲。歌词以“wild rose”(野玫瑰)的比喻,塑造了一个集甜美和狂野于一身的女性形象。一方面,她作为男性凝视的产物...
关键词:凝视理论 女性主义 他者 摇滚乐 
基于英语学习活动观的初中英语分级阅读教学实践——以Nick Nelly and Jack为例被引量:3
《英语教师》2021年第17期117-120,共4页付俊华 
分析初中英语分级阅读教学现状及基于英语学习活动观开展分级阅读的意义。以《多维阅读》13级阅读文本Nick Nelly and Jack为例,探讨英语学习活动观在初中英语分级阅读教学中的具体应用。提出在初中英语分级阅读教学中,教师应基于英语...
关键词:英语学习活动观 初中英语 分级阅读 
Shortening the sgRNA-DNA interface enables SpCas9 and eSpCas9(1.1)to nick the target DNA strand被引量:4
《Science China(Life Sciences)》2020年第11期1619-1630,共12页Rong Fan Zhuangzhuang Chai Sinian Xing Kunling Chen Fengti Qiu Tuanyao Chai Jin-Long Qiu Zhengbin Zhang Huawei Zhang Caixia Gao 
supported by grants from the Strategic Priority Research Program of the Chinese Academy of Sciences(Precision Seed Design and Breeding,XDA24020102);the National Transgenic Science and Technology Program(2018ZX0801002B);the National Natural Science Foundation of China(31788103 and 31971370);the Chinese Academy of Sciences(QYZDY-SSW-SMC030);the National Key R&D Program of China(2018YFA0900600,2016YFD0100102-11,and 2016YFD0100605)。
The length of the sgRNA-DNA complementary sequence is a key factor influencing the cleavage activity of Streptococcus pyogenes Cas9(SpCas9)and its variants.The detailed mechanism remains unknown.Here,based on in vitro...
关键词:SpCas9 eSpCas9(1.1) truncated spacer DSB nickase co-editing 
PRINTED IN NORTH KOREA Nick Bonner Discusses His DPRK Art Collection
《城市漫步(上海版、英文)》2020年第5期12-15,共4页Ned Kelly 
Koryo Tours founder Nick Bonner first visited the Democratic People's Republic of Korea(DPRK),commonly known as North Korea,in 1993 and immediately started exploring the the nation's art world-collecting works,meeting...
关键词:PRINT Korea RELEASE 
An Analysis Of Nick’s Moral Evolution Process In Graet Gatsby From The Perspective Of Kohlberg’s Theory In Stages Of Moral Development
《校园英语》2020年第16期251-251,共1页黄中梅 李雪婷 
Based on Lawrence Kohlberg’s theory of the stages of moral development,this paper studies the evolution of Nick’s moral values,and further makes an in-depth and systematic analysis of the factors affecting Nick’s m...
关键词:NICK KOHLBERG MORAL NARRATOR PARTICIPANT 
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