the Development of Sustainable Application for Standard Herbal Resource by the Korea Institute of Oriental Medicine (No. KSN2012320)。
OBJECTIVE: To assess Atractylodis Rhizoma Alba extract(ARE) neuroprotective function in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine(MPTP)-treated mice and related genes. METHODS: Examined m RNA-DNA methylation change...
the Project of National Famous Old Chinese Medicine Experts Inheritance Studio Construction:the National Project of Taking Inheriting Experience of Prestigious Chinese Physicians Wang Linpeng(No.ZY202275)。
OBJECTIVE:To explore the effect of electroacupuncture on skeletal muscle pain in Parkinson's disease(PD).METHODS:A single-center randomized controlled trial was conducted with sixty patients with Parkinson's disease w...
Supported by National Natural Science Foundation of China:Study on the Mechanism of Regulating miR-124 by Tongdu Tiaoshen Acupuncture to Promote Neuroprotection in Cerebral Ischemia Reperfusion Injury(No.81973933);Natural Science Fund for Colleges and Universities in Anhui Province:Study on the Regulatory Mechanism of Tongdu Tiaoshen Acupuncture on Dopaminergic Neurons in Parkinson’s Disease Model Mice Based on Mitochondrial Autophagy(No.KJ2019A0475)。
OBJECTIVE:To explore the possible mechanism of Tongdu Tiaoshen acupuncture combined with Xiaoxuming decoction(小续命汤,XXMD)in the treatment of Parkinson’s disease(PD).METHODS:C57BL/6 mice were randomly divided into ...
Supported by the Open Fund of Key Laboratory of Dunhuang Medicine,Ministry of Education(DHYX20-09);the Youth Research Foundation of the Gansu University of Chinese Medicine(No.ZQ2017-14)。
OBJECTIVE:To investigate the protective effect of resveratrol on cardiomyocytes after hypoxia/reoxygenation intervention based on PTEN-induced putative kinase protein 1/Parkinson disease protein 2(PINK1/PARKIN)signali...
Supported by the Creation of Major New Drugs for Major National Science and Technology Projects(No.2019ZX09301154);National Natural Science Foundation of China(Nos.81904263,81804156);2021 Fujian Provincial Traditional Chinese Medicine Science and Technology Program;2018 Outstanding Young Scientific Research Project in Fujian province。
OBJECTIVE:To investigate the effect of Roucongrong(Herba Cistanches Deserticolae)decoction on the substantia nigra in rats with Parkinson’s disease(PD)induced by 6-hydroxydopamine hydrochloride(6-OHDA).To further det...
Supported by the Korea Institute of Oriental Medicine:the Verification of Efficacy and Safety for Chung-bu Medicinal Materials Described in the Dong Ui Bo Gam (K18411);Applicational Development of Standardized Herbal Resources (KSN1911420)。
OBJECTIVE: To investigate whether scorpion extract elicits a neuroprotective effect in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine(MPTP)-treated mice models, and the genes associated with the therapeutic effects usin...
Supported by Clinical Study on Treatment of Parkinson’s Disease with Sleep Disorder in Symptom Pattern of Phlegma-heat-stirring Wind Due to by Huatan Jieyu granules (No.2017-D-YY-70)。
OBJECTIVE: To investigate the safety and efficacy of Huatan Jieyu granules in treatment of Parkinson’s disease(PD) patients with sleep disorder identified as symptom pattern of phlegma-heat-stirring wind in terms of ...
Supported by the Dongguk University Research Fund of 2014
OBJECTIVE:To examine the role of KSOP1009(a modified formulation of Suhexiang Wan essential oil)in an animal model of Parkinson's disease(PD)induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydro-pyridine(MPTP)injection.METH...
Supported by Surface Project of National Natural Science Foundation of China,"TCM Compound Rehmannia Formula Regulating Basal Ganglia Loop to Treat Parkinson's Disease"(No.30973722);Surface Project of National Natural Science Foundation of China"Mechanism of TCM Compound Rehmannia Granule Regulating MAPK/ERK Signaling Pathway in Parkinson's Disease"(No.81573899);Shanghai TCM Research and Technology Support Project"Development of TCM Compound Rehmannia Granule Treating Parkinson's Disease"(No.12401900302);Shanghai TCM Research and Technology Support Project"Toxicological Research on TCM Compound Rehmannia Granules Treating Parkinson's Disease"(No.16401902400);Shanghai Municipal Health Bureau Scientific Research Project"Based on the Neural Plasticity Compound Rehmannia Treating Parkinson's Disease"(No.2012J009A)
OBJECTIVE: To use the theory of Traditional Chinese Medicine to identify the major symptom patterns of Parkinson's disease.METHODS: Journal databases were searched for relevant articles in the last 30 years. Articles ...
Based on the long-term clinical practice and scientific researches on the three methods for the stage-treatment of Parkinson's disease put forward by the author in the early years, this essay further discusses the di...