PARKINSONS

作品数：206被引量：380H指数：9
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相关领域：医药卫生生物学更多>>
相关作者：王宏梅王奇王奇更多>>
相关机构：辽东学院安徽医科大学广州中医药大学中山大学更多>>
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相关基金：国家自然科学基金国家重点基础研究发展计划北京市自然科学基金国家高技术研究发展计划更多>>
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Effects of Physical Activity Levels on Fatigue Perception in Patients with Parkinson’s Disease and Neurologically Healthy Individuals
《Health》2014年第21期2927-2933,共7页Paulo Cezar Rocha dos Santos Fabio Augusto Barbieri Diego Orcioli-Silva Lucas Simieli Lilian Teresa Bucken Gobbi 
Background: Recent researches involving fatigue and Parkinson’s disease (PD) sought to verify its incidence and the impacts of fatigue on quality life of patients with PD. Despite the importance of regular physical a...
关键词：Parkinson’s Disease SYMPTOM of FATIGUE Physical Activity Levels NON-MOTOR SYMPTOM 
Non-motor signs and symptoms in Parkinson’s disease
《Health》2012年第11期1133-1137,共5页Kazuo Abe 
Motor symptoms are cardinal clinical features of Parkinson’s disease (PD). Progress in drug therapy and rehabilitation has been presenting beneficial effect for motor symptoms. However, non-motor symptoms and signs i...
关键词：Parkinson’s Disease (PD) NON-MOTOR SIGNS and SYMPTOMS Activities of Daily Livings (ADL) Quality of Life (QOL) 
Pharmacological strategies for Parkinson’s disease
《Health》2012年第11期1153-1166,共14页José-Rubén García-Montes Alejandra Boronat-García René Drucker-Colín 
Parkinson’s disease (PD) or Paralysis Agitans was first formally described in “An essay on the shaking palsy”, published in 1817 by a British physician named James Parkinson. In the late 1950’s, dopamine was relat...
关键词：Parkinson’s Disease PHARMACOLOGICAL STRATEGIES Preventive AGENTS DOPAMINERGIC AGENTS L-DOPA 
Alpha-synuclein truncation and disease
《Health》2012年第11期1167-1177,共11页Caroline M. Ritchie Philip J. Thomas 
Alpha-synuclein is the major component of Lewy bodies, insoluble protein aggregates, found in patients with Parkinson’s disease, diffuse Lewy body disease, and the Lewy body variant of Alzheimer’s disease. Alpha-syn...
关键词：ALPHA-SYNUCLEIN Neurodegeneration Parkinson’s DISEASE LEWY Body PROTEASOME TRUNCATION Degradation Aggregation Protease 
Unilateral 6-OHDA <i>th-fgfr1</i>(<i>tk-</i>) mouse model supports the role of FGFs in Parkinson’s disease and the effects of nicotine and L-DOPA on spontaneous motor impairments
《Health》2012年第11期1178-1190,共13页Aaron Kucinski Scott Wersinger Ewa K. Stachowiak Milen Radell Renae Hesse Thomas Corso Matthew Parry Merouane Bencherif Kristen Jordan Sharon Letchworth Michal K. Stachowiak 
In the developing and adult brain, neurotrophic growth factors support the growth and protec tion of dopaminergic neuronal systems. Recently, links between impaired neurotrophin support of dopamine (DA) neurons has be...
关键词：Parkinson’s Disease Fibroblast Growth Factor (FGF) Signaling Transgenic Mouse NICOTINE L-DOPA 
Recent advances in pharmacological therapy of Parkinson’s disease: Levodopa and carbidopa protective effects against DNA oxidative damage
《Health》2012年第11期1191-1199,共9页Monica Colamartino Luca Padua Tommaso Cornetta Antonella Testa Renata Cozzi 
Parkinson’s disease is one of the most common progressive neurodegenerative disorder. It is characterized by the depletion of dopamine in the dopaminergic neurons of the striatum of the brain. Pharmacological treatme...
关键词：Parkinson’s DISEASE LEVODOPA CARBIDOPA Protective Effects 
Diagnostics, rehabilitation and models of Parkinson’s disease
《Health》2012年第11期1200-1217,共18页Juliana Dushanova 
Diagnostics and rehabilitation of Parkinson’s disease (PD) presents the current information pertaining to etiology, early biomarkers for diagnostics, novel methods to evaluate symptoms, multidisciplinary rehabilitati...
关键词：Parkinson’s DISEASE DIAGNOSTICS REHABILITATION MODELS 
The interaction between the dopaminergic and the serotonergic systems in the 6-OHDA rat model of Parkinson’s disease
《Health》2012年第11期1218-1224,共7页Daphna Sourani Gadi Goelman 
This review summarizes published results that are related to the coupling between the dopaminergic and the serotonergic systems and their association to Parkinson’s disease. We focus on the 6-hydroxydopamine rat mode...
关键词：Parkinson’s Disease Depression 6-HYDROXYDOPAMINE Lateral HABENULA Manganese-Enhanced-MRI 
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