PROTECTIVE_EFFECT

作品数:622被引量:1922H指数:19
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相关作者:张晓林张祥建陈晓春王春波王跃军更多>>
相关机构:复旦大学福建医科大学北京大学河北医科大学第二医院更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划北京市自然科学基金中国博士后科学基金更多>>
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Goji berry-derived phenylpropionyl phenylethylamine derivatives protect against ethanol-induced hepatic damage
《Food Science and Human Wellness》2025年第3期1139-1147,共9页Zhengqun Zhou Zhaodi Che Jiancong Mai Rui Zhang Zhihui Luo Yifang Li Kwokfai So Jia Xiao Xinsheng Yao Hao Gao 
funded via National Natural Science Foundation of China(81925037,82321004,U22A20371,and 82273801);Guangdong Major Project of Basic and Applied Basic Research(2023B0303000026);Guangdong International Science and Technology Cooperation Base(2021A0505020015);Innovative and Research Teams Project of Guangdong Higher Education Institution(2021KCXTD001);Guangdong Basic and Applied Basic Research Foundation(2022A1515012071);Young Elite Scientists Sponsorship Program by China Association of Chinese Medicine(2021-QNRC2-B21);Guangdong-Hong Kong-Macao Universities Joint Laboratory for the Internationalization of Traditional Chinese Medicine(2023LSYS002);Guangzhou Key Laboratory of Traditional Chinese Medicine&Disease Susceptibility(2024A03J090);Science and Technology Program of Guangzhou(201707010414,202201020066,and 2024A04J9955)。
Goji berry is a famous edible and medicinal substance around the world.In this research,15 phenylpropionyl phenylethylamine derivatives(1-15),in cluding one new compound(1),were separated and identified from g oji ber...
关键词:Goji berry Lycium barbarum Phenylpropionyl phenylethylamine derivatives Antioxidant activity He patoprotective effect 
Identification of phenolanine in rape bee pollen and its protective effect and mechanism on alcoholic liver injury
《Food Science and Human Wellness》2025年第2期484-496,共13页Cheng Lü Mingjuan Xu Xinbiao Yang Yanlun Feng Yun Zhu Qun Lu Chengming Wang Rui Liu 
supported by Key Research and Development Program of Hubei Province(2022BBA0072);Applied Fundamental Frontier Project of Wuhan Science and Technology Bureau(2020020601012271)。
Rape bee pollen has attracted increasing interests for its excellent protective effect against chemicalinduced liver injury owing to its abundant polyphenols.This study aims to analyze the types and contents of phenol...
关键词:Rape bee pollen Phenolamide Alcoholic liver disease(ALD) AML12s National Institute on Alcohol Abuse and Alcoholism(NIAAA) TRANSCRIPTOME 
Alkali-extracted polysaccharides from mung bean skin possess protective effect on H_(2)O_(2)-induced IEC-6 cells:the role of NF-κB and MAPK signaling pathways
《Food Science and Human Wellness》2025年第1期101-111,共11页Shuai Chen Liuming Xie Pingwei Wen Qiang Yu Yi Chen Hanyu Lu Ting Chen Xin Tao Jianhua Xie 
financially supported by the National Key Research and Development Program of China(2023YFF1104001);Natural Science Foundation of Jiangxi Province,China(20232BCD44003);National High-Level Talents Special Support Program of China(202212)。
Intestinal oxidation-reduction balance is essential to protect host health.Research on the underlying mechanisms of oxidation homeostasis can provide conditions to the treatment or protection of intestinal oxidative s...
关键词:POLYSACCHARIDE Alkali-extracted Oxidative stress RNA sequencing Molecular mechanism 
Capsaicin(CAP)exerts a protective effect against ethanol-induced oxidative gastric mucosal injury by modulating the chemokine receptor 4(CCR4)/Src/p47phox signaling pathway both in vitro and in vivo
《Chinese Journal of Natural Medicines》2025年第2期191-202,共12页Zhiru Yang Haolin Guo Pengfei Zhang Kairui Liu Junli Ba Xue Bai Shiti Shama Bo Zhang Xiaoning Gao Jun Kang 
supported by the High-level Talent Research Start-up Project Funding of Henan Academy of Sciences (No.252028037)。
Ethanol(EtOH)is a common trigger for gastric mucosal diseases,and mitigating oxidative stress is essential for attenuating gastric mucosal damage.Capsaicin(CAP)has been identified as a potential agent to counteract ox...
关键词:CAPSAICIN Gastric mucosal damage Chemokine signaling NF-κB p65 
Protective effect of marine animal hydrolysis-peptides on adjuvant-induced arthritis in mice by gut microbiota and short-chain fatty acids
《Food Science and Human Wellness》2025年第1期361-370,共10页Zhen Zhang Shasha Tang Ziyan Wang Jiaojiao Han Jun Zhou Chenyang Lu Bin Liu Xiaoling Sun Rongxian Yu Rixin Wang Xiurong Su 
sponsored by the National Key R&D Program of China(2019YFD0900101);One Health Interdisciplinary Research Project,Ningbo University,KC Wong Magna Fund in Ningbo University;the National Natural Science Foundation of China(42106122);the Natural Science Foundation of Zhejiang Province(LGC22C190002)。
Marine fauna provides a plentiful repository of peptides and bioactive proteins.Peptides and proteins isolated from marine animals have been studied and applied in the development of food supplements,drugs,and cosmece...
关键词:Marine animals-derived peptides Adjuvant-induced arthritis Gut flora Short-chain fatty acid 
Protective effect of lappaconitine on Freund's complete adjuvant-induced arthritis exerted through P2X7 receptor-mediated regulation of M1/M2 balance in rats
《Journal of Traditional Chinese Medicine》2025年第1期39-48,共10页ZHANG Pengqiang FENG Qi HUANG Weiyan OU Shan 
OBJECTIVE:to investigate the anti-arthritic effects of lappaconitine(LA)on adjuvant-induced arthritis in Sprague-Dawley rats and its possible involvement in the regulation of M1/M2 macrophage balance through the P2X7 ...
关键词:arthritis experimental macrophage polarization receptors purinergic P2X7 anti-inflammatory agents ANALGESICS LAPPACONITINE 
Autophagy serves as a protective effect against inflammatory injury of oxidative stress in ARPE-19 cell
《International Journal of Ophthalmology(English edition)》2025年第1期28-38,共11页Na-Na Meng Lei-Zhou Xia Yi-Qing Gong Pei-Rong Lu 
Supported by the Science and Technology Planning Social Development Project of Zhenjiang City(No.FZ2022132,No.FZ2023062,No.SH2023041);Foundation of Jinshan Doctor of Zhenjiang City(No.2021-JSYZ-13);Foundation of the Affiliated People’s Hospital of Jiangsu University(No.KFB2020005,No.KFQM-08).
AIM:To test the effect of autophagy on inflammatory damage resulting from oxidative stress in adult retinal pigment epithelial cell line(ARPE-19).METHODS:ARPE-19 cells were pretreated with 200 and 600μmol/L hydrogen ...
关键词:retinal pigment epithelium AUTOPHAGY reactive oxygen species INFLAMMATION 
Dermatoprotective Effect of Ocoxin Cream® in Cancer Patients Treated with Radiation Therapy. Case Series
《Case Reports in Clinical Medicine》2025年第1期25-39,共15页Iris B. Inguanzo-Valdés Helga Candanedo-Pazo Aixa Ulloa-Balmaseda Oslay Cervantes-Hernández Acralis de La Cruz-Galguera Martha Lugioyo-Lugo Rosa M. Ortiz-Reyes Mircea Betancourt-Cabeza Jorge Luis Soriano-García Ramón Ropero-Toirac 
Background: The effects of radiation therapy can impact patients’ quality of life, leading to treatment interruptions and therefore sub-optimal outcomes. The main aim was to evaluate the preliminary effects of Ocoxin...
关键词:DERMATITIS Radiation Therapy Ocoxin Cream® Quality of Life 
Protective Effect of Liraglutide on Early Renal Fibrosis in Diabetes Mice
《Journal of Biosciences and Medicines》2025年第1期84-91,共8页Xiaolan Ke Te’an Ma 
Background: In recent years, studies have shown that liraglutide may delay the progression of renal fibrosis by inhibiting renal fibrosis signaling pathways and reducing collagen deposition. TGF-β1 and E-Cadherin pla...
关键词:LIRAGLUTIDE DIABETES Renal fibrosis TGF-β1 E-CADHERIN 
Protective Effect of Selenium Supplementation on Cerebral Ischemia-Reperfusion Injury after Ischemic Stroke
《Journal of Biosciences and Medicines》2025年第1期184-195,共12页Mingtian Lu Zehua He Zhejing Ding Zhengwei Chen Tianyang Guan Zhongliang Li Guomin Huang Guangsen Cheng Shaoqin Liao Yu Liu 
With the wide application of thrombolytic drugs and the advancement of endovascular therapeutic techniques, the recanalization treatment of acute artery occlusion in ischemic stroke (IS) has made a leap forward, but i...
关键词:SELENIUM Ischemic Stroke Cerebral Ischemia-Reperfusion Injury GPx4 
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