云南高校图书馆联盟文献共享服务平台- SOMAN

SOMAN: 作品数：17被引量：8H指数：1; 导出分析报告; 相关领域：医药卫生理学更多>>; 相关作者：景德强陈尔瑜周廷冲王玉霞孙曼霁更多>>; 相关机构：第三军医大学军事医学科学院第二军医大学北京药物化学研究所更多>>; 相关期刊：《Neuroscience Bulletin》《神经解剖学杂志》《中国海洋药物》《Acta Pharmacologica Sinica》更多>>; 相关基金：国家自然科学基金更多>>

Review: Practical Use of a Neurophysiological Detector and the Protocol for High-Performance Liquid Chromatography: 《International Journal of Analytical Mass Spectrometry and Chromatography》2023年第1期1-10,共10页Ilia Brondz; The main aim for discovery and development of the neurophysiological detector was detection of the production’ seats and criminal use of poisons in warfare. Phosphor-organic (PO) substances with acetylcholinesterase-...; 关键词：Neurophysiological Detector Phosphor-Organic Substances TABUN SOMAN Criminal Use of Poisons in Warfare

TRPV4 Regulates Soman-Induced Status Epilepticus and Secondary Brain Injury via NMDA Receptor and NLRP3 Inflammasome被引量：3: 《Neuroscience Bulletin》2021年第7期905-920,共16页Shuai Wang Huanhuan He Jianhai Long Xin Sui Jun Yang Guodong Lin Qian Wang Yongan Wang Yuan Luo; the Special Fund for Military Medical Science(AWS15J007 and BWS16J007);the National Natural Science Foundation of China(81703505).; Nerve agents are used in civil wars and terrorist attacks,posing a threat to public safety.Acute exposure to nerve agents such as soman(GD)causes serious brain damage,leading to death due to intense seizures induced b...; 关键词：Nerve agents SOMAN TRPV4 NMDA receptor NLRP3 inflammasome

The influence of ultraviolet blood irradiation and oxygenation on oxygen free radicals metabolism in rabbits with soman intoxication: 《Journal of Medical Colleges of PLA(China)》2006年第1期42-44,共3页张献清张晓迪穆士杰陈蕤夏爱军梁欣海春旭; Objective: To investigate the effect of ultraviolet blood irradiation and oxygenation (UBIO) on the metabolism of oxygen free radicals in rabbits with acute soman intoxication. Methods: One hundred rabbits were random...; 关键词：blood irradiation and oxygenation ultraviolet soman intoxication oxygen free radical

Experimental study on therapy of ultraviolet blood irradiation and oxygenation in acute soman intoxication in rabbits: 《Journal of Medical Colleges of PLA(China)》2005年第6期361-363,共3页张献清穆士杰张晓迪陈蕤夏爱军梁欣Department of Toxicology Fourth Military Medical University Xi'an 710032 China 海春旭Department of Toxicology Fourth Military Medical University Xi'an 710032 China; Objective:To study the therapy effect of ultraviolet blood irradiation and oxygenation （UBIO） on blood AChe activity and lung injury due to acute soman intoxication in rabbits. Methods:Forty rabbits were randomly di...; 关键词：ultraviolet blood irradiation and oxygenation soman lung injury ACETYLCHOLINESTERASE blood gas analysis

Influence of nimodipine on elimination of soman in rabbit blood and distribution of [3~H]soman in mice: 《Acta Pharmacologica Sinica》2002年第10期937-941,共5页李劲彤阮金秀袁淑兰张振清宋争艳王晓英; AIM: To investigate the effect of nimodipine on the elimination of soman in rabbit blood and distribution of [3H] soman in mice. METHODS: Chirasil capillary gas chromatographic analysis method with large volume inject...; 关键词：SOMAN NIMODIPINE gas chromatography drug metabolic detoxication area under curve

Y-Hydroxyphosphonate inducing single-chain antibodies capable of catalyzing soman hydrolysis: 《Science China Chemistry》2000年第6期649-656,共8页王字玲荣康泰杨日芳恽榴红; A γ-hydroxyphosphonate P6 (O1-methyl-O2-(1, 2, 2-trimethylpropyl)-2-hydroxy-5-nitro-phenyl methylphosphonic acid) which is proposed to be an analog of the transition state in hydrolysis of soman was synthesized. Arti...; 关键词：SOMAN catalytic antibody PHAGE display library.

Nitric oxide and soman poisoning被引量：1: 《中国药理学报》1998年第5期470-472,共3页王玉霞孙曼霁; 目的：探查索曼中毒机制是否有ＮＯ参与．方法：预先侧脑室注射Ａｒｇ、ＮＡＭＥ，观察索曼中毒小鼠惊厥潜伏期、死亡率及脑中ＮＯＳ活性变化．结果：Ａｒｇ预处理时，潜伏期从５２ｍｉｎ（对照组）缩短到４３ｍｉｎ（Ａｒｇ１６０...; 关键词：索曼一氧化氮中毒毒理学

SOMAN诱发惊厥后c-fos在大鼠杏仁核簇─氧化氮神经元中的表达: 《神经解剖学杂志》1998年第2期174-178,共5页景德强陈尔瑜余争平程天民; 运用FOS免疫组化结合NADPH－d组化双重标记技术，研究了soman诱发惊厥大鼠杏仁核内c－fos高表达神经元与NADPH－d阳性神经元之间的关系。结果显示：在soman诱发惊厥后的1．5h至48h，杏仁核簇内c－fos呈现持续过度表达、FOS免疫阳性神经...; 关键词：C-FOS NO 杏仁核 SOMAN 惊厥大鼠

Protooncogene c-fos overexpression in NADPH-d positive neurons of the amygdala in soman induced seizures in the rat: 《Journal of Medical Colleges of PLA(China)》1998年第1期43-48,共6页景德强陈尔瑜余争平程天民; Fos immunohistochemistry and NADPH-d histochemistry and double labeling of the 2 methods were used to study therelationship between c-Fos expressed neurons and NADPH-d positive neurons of the amygdala in soman-induced...; 关键词：C-FOS NITRIC oxide AMYGDALA SOMAN seilzure

Effects of hypoxia, soman and their combination on PC12 cells: 《Journal of Medical Colleges of PLA(China)》1997年第3期173-176,共4页余争平程天民伊规须英辉; To investigate the effects of hypoxia, soman and their combined ones on PC12 cells. Methods: After the PC12 cells were exposed to an atmosphere containing different concentrations of oxygen and cultured in a medium co...; 关键词：HYPOXIA SOMAN CYTOTOXICITY combined effect LACTIC DEHYDROGENASE (LDH) PC12 cell

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