AIM:To assess early visual outcomes and corneal stability following small incision lenticule extraction(SMILE)in eyes with a pre-planned residual stromal thickness(RST)ranging from 280 to 300μm.METHODS:This retrospec...
Supported by the Science&Technology Department of Sichuan Province(China)Funding Project(No.2021YFS0221,No.2023YFS0179);1.3.5 Project for Disciplines of Excellence,West China Hospital,Sichuan University(No.2022HXFH032,No.ZYJC21058);the Postdoctoral Research Funding of West China Hospital,Sichuan University,China(No.2020HXBH044).
●AIM:To explore the clinical efficacy and safety of stromal lenticule addition keratoplasty(SLAK)with corneal crosslinking(CXL)on patients with corneal ectasia secondary to femtosecond laser-assisted in situ keratomi...
AIM:To review recent innovations,challenges,and applications of small incision lenticule extraction(SMILE)extracted lenticule for treating ocular disorders.METHODS:A literature review was performed in the PubMed datab...
Supported by the National Key Research and Development Program of China(No.2020YFE0204400);the National Natural Science Foundation of China(No.82271042);the Zhejiang Province Key Research and Development Program(No.2023C03090).
A corneal epithelial-stromal defect is recognized as a major contributor to corneal scarring.Given the rising prevalence of blindness caused by corneal scarring,increasing attention has been focused on corneal epithel...
the project with number IR.SBMU.RETECH.REC.1399.024 from Student Research Committee,Department of Optometry,Faculty of Rehabilitation,Shahid Beheshti University of Medical Sciences,Tehran,Iran;the“Student Research Committee”and“Research&Technology Chancellor”in Shahid Beheshti University of Medical Sciences for their financial support of this study。
·AIM: To evaluate the efficacy and safety of intrastromal transplantation of adipose-derived stem cells(ASCs) in keratoconus patients.·METHODS: This study was conducted on 8 eyes of 8 patients with moderate to sever...
Supported by the National Key R&D Program of China (No.2016YFC1100100);the Key R&D Program of Shaanxi Province (No.2018ZDXM-SF-056);the Health and Family Planning Research Fund Project of Shaanxi Province (No.2016C004);the Key Research and Development Program of Shaanxi Province (No.2019SF-196);the Research Talent Project of Xi’an Municipal Health Commission (No.J201902037)。
Corneal stroma-derived mesenchymal stem cells(CS-MSCs) are mainly distributed in the anterior part of the corneal stroma near the corneal limbal stem cells(LSCs). CS-MSCs are stem cells with self-renewal and multidire...
Supported by the National High Technology R&D Program of China(No.2006AA02A132)
AIM: To reveal the cytotoxicity and related mechanisms of gatifloxacin(GFX) to stromal fibroblasts(SFs) in vitro.METHODS: SFs were treated with GFX at different concentrations(0.009375%-0.3%), and their viability was ...
Supported by Natural Science Foundation of Hunan Province(No.2016JJ2163);Natural Science Foundation of Hubei Province(No.2015CFC837);Health and Family Planning Committee Science Foundation of Hubei Province(No.WJ2015MB259);Health and Family Planning Committee Science Foundation of Wuhan Municipality(No.WX17A13)
AIM: To compare the clinical and microstructural changes induced by different transepithelial iontophoresis-assisted corneal cross-linking(I-CXL) methods for keratoconus. METHODS: A total of 42 eyes of 42 patients wit...
Supported in part by the National Natural Science Foundation of China(No.11402161);the Programs for Science and Technique Development of Shanxi Province,China(No.20120313025-3);the Science and Technology Research Projects of the Shanxi Provincial Health Department,China(No.201201018);an unrestricted grant from Research to Prevent Blindness,New York,NY,USA
AIM: To investigate the long term(≥5 y) efficacy, predictability, and safety of laser in situ keratomileusis(LASIK) in eyes with thin corneas [central corneal thickness(CCT) 〈500 μm]. METHODS: A total of 33...
AIMTo evaluate the clinical findings of toxic keratopathy associated with abuse of topical anesthetics and the treatment efficacy of amniotic membrane transplantation (AMT).METHODSFifteen eyes of 10 patients with abus...