BACKGROUND Organ donation and transplantation are vital for saving lives,yet awareness remains limited.Health literacy,the ability to understand and use health information,and self-control,which influences decision-ma...
Oxidative stress is characterized by elevated intracellular reactive oxygen species(ROS)levels.At physiological levels,ROS work as signaling molecules,helping cells go through the cell cycle normally and keeping their...
Supported by the National Key Research and Development Program of China,No.2022YFC2503600。
BACKGROUND The discrepancy between endoscopic biopsy pathology and the overall pathology of gastric low-grade intraepithelial neoplasia(LGIN)presents challenges in developing diagnostic and treatment protocols.AIM To ...
supported by funding from the Zhejiang Provincial Key Research and Development Program(No.2021C03107 to S.H.);the Leading Talent of Scientific and Technological Innovation-“Ten Thousand Talents Program”of Zhejiang Province(No.2021R52016 to S.H.);the National Natural Science Foundation(No.82172770 to P.F.);the Fundamental Research Funds for the Central Universities(226-2022-00193,226-2022-00002).
Epidemiological evidence indicates that major depressive disorder(MDD)may predispose the development and prognosis of breast cancer(BC)in females[1].However,the mechanisms linking these phenotypes are not fully unders...
The role of Toll-like receptor 4 (TLR4) and nuclear factor κB p65 (NF-κB p65) proteins in the pathogenesis of otitis media is explored. In recent years, the incidence of otitis media has been rising globally, becomi...
Breast cancer exhibits the second-highest incidence and fourth-highest mortality rates worldwide based on current global cancer statistics.1Significant advances such as surgical resection, radiation therapy, chemother...
MicroRNAs(miRNAs)are recognized for their involvement in the regulation of gene expression and exhibit significant potential in both the prognostic assessment and treatment of hepatocellular carcinoma(HCC).HCC,like ot...
Supported by Tianjin Key Medical Discipline(Specialty)Construction Project,No.TJYXZDXK-009A;Tianjin Medical University Cancer Hospital National Natural Science Foundation Cultivation Program,No.220108;National Natural Science Foundation of China,No.82373134;Science and Technology Development Fund of Tianjin Education Commission for Higher Education,No.2022KJ228;Chinese Anti-Cancer Association-Heng Rui Anti-angiogenesis Targeted Tumor Research Fund,No.2021001045;and Scientific Research Translational Foundation of Wenzhou Safety(Emergency)Institute of Tianjin University,No.TJUWYY2022025.
BACKGROUND Esophageal squamous cell carcinoma(ESCC)is a deadly malignancy with limited treatment options.Deubiquitinases(DUBs)have been confirmed to play a crucial role in the development of malignant tumors.JOSD2 is ...
Objective:To analyze the diagnostic value of frozen section pathology in the diagnosis of breast cancer.Methods:A total of 50 patients with breast tumors treated between July 2021 and February 2023 were randomly selec...
National Natural Science Foundation of China,Grant/Award Numbers:92268107,82170476;Natural Science Foundation of Beijing,China,Grant/Award Number:M21008。
Antiphospholipid syndrome(APS)is typically characterized by increased levels of three classes of antiphospholipid antibodies,namely lupus anticoagulant,anti-β2-glycoprotein I(anti-β2GPI),and anticardiolipin antibodi...