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作品数：656被引量：1797H指数：16
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DDX24 promotes lymphangiogenesis and lymph node metastasis via AGRN production in cervical squamous cell carcinoma
《Chinese Medical Journal》2025年第3期361-363,共3页Baibin Wang Yuan Zhuang Chongrong Weng Yanhui Jiang Bingfan Xie Lijie Wang Yingying Dong Xiangpei Fang Jianzhong He Xiaojin Wang Huanhuan He Yong Chen Huilong Nie 
National Natural Science Foundation of China(Nos.92159105 and 81872113);Guangdong Province(No.2020A0505100028)
To the Editor:Cervical cancer(CC)is the second leading cause of cancer death in women,representing a major global health challenge.[1]Cervical squamous cell carcinoma(CSCC)accounts for 70%of CC cases,and pelvic lymph ...
关键词：pelvic lymph node metastasis squamous cell carcinoma cscc accounts ddx cervical squamous cell carcinoma agrn LYMPHANGIOGENESIS underlying mechanisms lymph node metastasis 
RNF213 in moyamoya disease:Genotype-phenotype association and the underlying mechanism
《Chinese Medical Journal》2024年第21期2552-2560,共9页Jianxun Fang Xinzhuang Yang Jun Ni 
supported by grants from STI2030-Major Project#2021ZD0201100 Task 5#2021ZD0201105;National High Level Hospital Clinical Research Funding(No.2022-PUMCH-D-007).
Moyamoya disease(MMD)is a cerebrovascular disorder characterized by a steno-occlusive internal carotid artery and compensatory vascular network formation.Although the precise pathogenic mechanism remains elusive,genet...
关键词：Moyamoya disease RNF213 POLYMORPHISM p.R4810K 
Prognostic significance and underlying mechanisms of STING in lung adenocarcinoma
《Chinese Medical Journal》2024年第20期2501-2503,共3页Haohua Zhu Yufeng Cao Jingyu Lu Lei Guo Rongrong Luo Huiyang Shi Yu Feng Yutao Liu Puyuan Xing Hongyu Wang Yuankai Shi Jie Ma Xingsheng Hu 
founded by Beijing Xisike Clinical Oncology Research Foundation(No.Y-2019AZMS-0439).
To the Editor:Genomic instability is a hallmark of cancer,with increasing genetic changes and DNA damage.The accumulated mutations in the tumor genome can generate neoantigens,which can trigger an antitumor immune res...
关键词：INTERFERON STIMULATOR ADENOCARCINOMA 
Subsequent strategies and underlying mechanism of acquired resistance to PD-1 axis inhibitors in advanced non-small cell lung cancer
《Chinese Medical Journal》2024年第7期880-882,共3页Huilan Wang Xinyu Cheng Fan Yang Lu Chen Anmei Zhang Liangzhi Zhong Haixia Long Bo Zhu Zhongyu Wang 
National Natural Science Foundation of China(No.82173097 to Z.W.);National Key Research&Development Program of China(Nos.2022YFC2505000 and 2022YFC2505002 to H.L.)
To the Editor:With the widespread application of immune checkpoint inhibitors(ICIs)in clinical practice,acquired resistance(AR)to programmed death-1(PD-1)/programmed death ligand 1(PD-L1)axis inhibitors in advanced no...
关键词：ROUTINE alterations resistance 
Prevalence, risk factors, and survival associated with pulmonary hypertension and heart failure among patients with underlying coronary artery disease: a national prospective, multicenter registry study in China被引量：8
《Chinese Medical Journal》2022年第15期1837-1845,共9页Li Huang Lingpin Pang Qing Gu Tao Yang Wen Li Ruilin Quan Weiqing Su Weifeng Wu Fangming Tang Xiulong Zhu Jieyan Shen Jingzhi Sun Guangliang Shan Changming Xiong Shian Huang Jianguo He 
National Key Technology R&D Program of China(No. 2011BAI11B15);National Key Research and Development Program of China(No. 2016YFC1304400)。
Background: Coronary artery disease (CAD) is the commonest cause of heart failure (HF), whereas pulmonary hypertension (PH) has not been established or reported in this patient population. Therefore, we assessed the p...
关键词：Coronary artery disease Heart failure Pulmonary hypertension Registry study 
Identification of key genes underlying the effects of obesity on knee osteoarthritis被引量：1
《Chinese Medical Journal》2022年第4期474-476,共3页Siming Dai Juan Zhang Xiaoying Zhu Yuxuan Lin Ying Cui Zhiyi Zhang Zhiguo Lin 
This work was supported by grants from the National Natural Science Foundation of China(Nos.81771749 and 81901638);Harbin Technology Bureau Research Fund(No.2017RAQXJ196);Scientific Research Innovation Foundation of the First Affiliated Hospital of Harbin Medical University(No.2019B18)。
To the Editor:Osteoarthritis(OA)is a disease associated with high morbidity and disability.Obesity,typically measured as a body mass index(BMI)≥30 kg/m2,is a well-known risk factor for the onset of OA and its related...
关键词：OBESITY DISEASES PATHOGENESIS 
Effects of CO2 fractional laser on hair growth in C57BL/6 mice and potential underlying mechanisms被引量：6
《Chinese Medical Journal》2019年第10期1257-1260,共4页Feng-Lin Zhuo Lin-Feng Li Liang-Qi Cai Yue Huang 
grants from the Beijing Natural Science Foundation (No. 7152040);the Youth Scientific Research Development Fund of The First Affiliated Hospital of Xiamen University (No. XYY2017007).
To the Editor: Hair loss or alopecia is a very common disease, which has the potential to impact the quality of life, physical attractiveness, and interpersonal relationships. In recent years, lasers and light therapy...
关键词：CO2 FRACTIONAL laser HAIR GROWTH 
Vascular Calcification： Current Genetics Underlying This Complex Phenomenon被引量：8
《Chinese Medical Journal》2017年第9期1113-1121,共9页Nonanzit Perez-Hernandez Gad Aptilon-Duque Ruben Blachman-Braun Gilberto Vargas-Alarcon Adrian Asael Rodriguez-Cortes Shely Azrad-Daniez Rosalinda Posadas-Sanchez Jose Manuel Rodriguez-Perez 
Objective： Vascular calcification is the consequence of the complex interaction between genetic, environmental, and vascular factors, which ultimately lead to the deposition of calcium in the tunica intima （atherosc...
关键词：ATHEROSCLEROSIS Cardiovascular Risk GENETICS POLYMORPHISMS Vascular Calcification 
Gene Expressions Underlying Mishandled Calcium Clearance and Elevated Generation of Reactive Oxygen Species in the Coronary Artery Smooth Muscle Cells of Chronic Heart Failure Rats被引量：10
《Chinese Medical Journal》2017年第4期460-469,共10页Liang Ding Xian-Xiu Su Wen-Hui Zhang Yu-Xiang Xu Xue-Feng Pan 
Background： The calcium clearance and reactive oxygen species （ROS） generations in the coronary artery smooth muscle cells in chronic heart failure （HF） have not been fully investigated. Therefore, we attempted t...
关键词：Calcium Clearance Chronic Heart Failure Nicotinamide Adenine Dinucleotide Phosphate Oxidase Sarco/Endoplasmic Reticulum Ca2^-ATPase Sodium-calciumExchanger 
Common underlying diseases do not contribute in determining the causes of sudden unexplained death
《Chinese Medical Journal》2013年第5期870-874,共5页TIAN Zhao-xing LV Yan-yu Chetan Rai Nugessur YAN Wei ZHAO Wen-kui KONG Li-li ZHENG Ya-an 
This study was supported by a grant from National Natural Science Foundation of China （No. 81172745）.
Background Underlying diseases have a statistically significant positive correlation to sudden death. However, sudden unexplained death （SUD） is different from sudden death, as there is no clinical evidence to suppo...
关键词：sudden unexplained death common underlying diseases death causes 
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