CANCER_CELL

作品数：220被引量：561H指数：13
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相关作者：郭鹏曾津芮红兵陈元仲陈炜更多>>
相关机构：西安交通大学医学院第一附属医院北京大学西安交通大学福建医科大学更多>>
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Functions and clinical significance of mechanical tumor microenvironment:cancer cell sensing,mechanobiology and metastasis被引量：8
《Cancer Communications》2022年第5期374-400,共27页Hanying Zhou Meng Wang Yixi Zhang Qingqing Su Zhengxin Xie Xiangyan Chen Ran Yan Ping Li Tingting Li Xiang Qin Hong Yang ChunhuiWu Fengming You Shun Li Yiyao Liu 
National Natural Science Foundation of China,Grant/Award Numbers:U19A2006,12132004,11972111,31900940,32071304,32171309,32171395;Sichuan Science and Technology Program,Grant/Award Number:21YJ0130;Joint Funds of Center for Engineering Medicine,Grant/Award Numbers:ZYGX2021YGLH017,ZYGX2021YGLH010,ZYGX2021YGLH023。
Dynamic and heterogeneous interaction between tumor cells and the surrounding microenvironment fuels the occurrence,progression,invasion,and metastasis of solid tumors.In this process,the tumormicroenvironment(TME)fra...
关键词：tumor microenvironment mechanical model MECHANOSENSING MECHANOTRANSDUCTION cytoskeleton remodelin 
Cancer cell reprogramming:a promising therapy converting malignancy to benignity被引量：4
《Cancer Communications》2019年第1期434-446,共13页Lanqi Gong Qian Yan Yu Zhang Xiaona Fang Beilei Liu Xinyuan Guan 
In the past decade, remarkable progress has been made in reprogramming terminally differentiated somatic cells and cancer cells into induced pluripotent cells and cancer cells with benign phenotypes. Recent studies ha...
关键词：Cancer cell reprogramming Transcription factor Small molecule MicroRNA EXOSOME MALIGNANCY BENIGN PLURIPOTENCY Cancer stem cell Induced pluripotent stem cell 
When fats commit crimes: fatty acid metabolism, cancer stemness and therapeutic resistance被引量：13
《Cancer Communications》2018年第1期499-510,共12页Ching-Ying Kuo David K.Ann 
supported in part by funds from the National Institutes of Health R01DE026304 and R01CA220693(to D.K.A.);Ministry of Science and Technology,R.O.C,Special Talents Award(to C.-Y.K).
The role of fatty acid metabolism,including both anabolic and catabolic reactions in cancer has gained increas-ing attention in recent years.Many studies have shown that aberrant expression of the genes involved in fa...
关键词：Fatty acid synthesis Fatty acid oxidation Fatty acid metabolism Lipogenic phenotype Cancer stem cells Tumor-initiating cells Cancer cell plasticity Therapeutic resistance Drug-tolerant persisters 
Tumor vasculature: a sally port for inhibiting cancer cell spreading被引量：2
《Cancer Communications》2018年第1期569-571,共3页Chao-Nan Qian Francesco Pezzella 
The close relationship between metastasis and establishment of tumor vasculature has inspired enormous research interests aiming to suppress metastasis via inhibiting the development of tumor vasculature.International...
关键词：INHIBITING METASTASIS BLOOD 
The 150 most important questions in cancer research and clinical oncology series: questions 94-101被引量：1
《Cancer Communications》2018年第1期736-744,共9页Cancer Communications 
Since the beginning of 2017,Cancer Communications(former title:Chinese Journal of Cancer)has published a series of important questions regarding cancer research and clinical oncology,to provide an enhanced stimulus fo...
关键词：Tumor origin Polyploid giant cancer cell Pancreatic ductal adenocarcinoma Biomarker Liquid biopsy Spontaneous animal model Metastasis Chemotherapy Immunotherapy Precision treatment Vaccine immunization Metformin Circulating tumor cell Circulating tumor DNA CpG methylation Methylation haplotype block PHYTOCHEMICALS P-GLYCOPROTEIN Multi-drug resistance P-Glycoprotein inhibitor Epithelial-to-mesenchymal transition Migration Pro-migratory gene 
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