CHOLINE

作品数：133被引量：439H指数：11
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相关机构：复旦大学成都军区昆明总医院四川大学华西医院山东大学更多>>
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Alternative splicing of a carboxyl/choline esterase gene enhances the fenpropathrin tolerance of Tetranychus cinnabarinus
《Insect Science》2023年第5期1255-1266,共12页Peng Wei Xinying Zeng Haonan Han Yiqing Yang Youjun Zhang Lin He 
supported in part by the National Nature Sciences Foundation(32001935 and 31972297);the Fundamental Research Funds for the Central Universities(SWU-KR22005).
Detoxification plays a crucial role in agricultural pests to withstand pesticides,and cytochrome P450s,carboxyl/choline esterases(CCEs),and glutathione-S-transferases are the main proteins responsible for their detoxi...
关键词：alternative splicing carboxyl/choline esterase(CCE) detoxification function PYRETHROID pests 
Long non-coding RNA GAS5 promotes PC12 cells differentiation into Tuj1-positive neuron-like cells and induces cell cycle arrest被引量：6
《Neural Regeneration Research》2019年第12期2118-2125,共8页He-Yan Zhao Sheng-Tong Zhang Xiang Cheng Hao-Ming Li Lei Zhang Hui He Jian-Bing Qin Wei-Ye Zhang Yan Sun Guo-Hua Jin 
supported by the National Natural Science Foundation of China,No.81501133(to HML);Postgraduate Research&Practice Innovation Program of Jiangsu Province of China,No.KYCX17-1931(to HYZ);Undergraduate Innovation and Entrepreneurship Training Project of Nantong University of China,No.2018150(to STZ);Pre-research Project of Natural Science Foundation of Nantong University of China,No.17ZY19(to HH);Scientific Research Fund Project of Nantong University Xinglin College of China,No.2018K131(to HYZ);Nantong Science and Technology Project of China,No.JC2018064(to HYZ)
Growth arrest-specific 5 (GAS5) is an anti-oncogene that has been extensively studied in tumors. However, research on GAS5 in the context of nervous system disease is rare at present. This study aimed to investigate t...
关键词：nerve REGENERATION growth arrest-specific 5 PC12 CELL neuron proliferation CELL cycle CHOLINE ACETYLTRANSFERASE ACETYLCHOLINE Alzheimer's disease neural REGENERATION 
Differential modulation of GABAA and NMDA receptors by α-nicotinic receptor desensitization in cultured rat hippocampal neurons
《Acta Pharmacologica Sinica》2016年第3期312-321,共10页Lei SHEN Wen-yu CUI Ru-zhu CHEN Hai WANG 
Aim： To explore the modulatory effect of desensitized a7-containing nicotinic receptors （（x7-nAChRs） on excitatory and inhibitory amino acid receptors in cultured hippocampal neurons and to identify the mechanism ...
关键词：α7 nicotinic receptors DESENSITIZATION GABA receptors NMDA receptors CHOLINE 
3rain protection against ischemic stroke using choline as a new molecular bypass treatment被引量：9
《Acta Pharmacologica Sinica》2015年第12期1416-1425,共10页Xin JIN Ru-huan WANG Hui WANG Chao-liang LONG Hai WANG 
Aim： To determine whether administration of choline could attenuate brain injury in a rat model of ischemic stroke and the underlying mechanisms. Methods： A rat model of ischemic stroke was established through perma...
关键词：ischemic stroke pMCAO rats CHOLINE METHYLLYCACONITINE NEOVASCULARIZATION α7 nicotinic acetylcholine receptor HIF-1Α VEGF ANGIOGENESIS brain microvascular endothelial cells 
Phosphatidylethanolamine N-methyltransferase and choline dehydrogenase gene polymorphisms are associated with human sperm concentration被引量：1
《Asian Journal of Andrology》2012年第5期778-783,共6页Leandros Lazaros Nectaria Xita Elissavet Hatzi Apostolos Kaponis Georgios Makrydimas Atsushi Takenaka Nikolaos Sofikitis Theodoros Stefos Konstantinos Zikopoulos Ioannis Georgiou 
Choline is a crucial factor in the regulation of sperm membrane structure and fluidity, and this nutrient plays an important role in the maturation and fertilizing capacity of spermatozoa. Transcripts of phosphatidyle...
关键词：choline dehydrogenase male infertility phosphatidylethanolamine N-methyltransferase PHOSPHOLIPIDS spermconcentration 
Quantification of choline concentration following liver cell apoptosis using ~1H magnetic resonance spectroscopy被引量：5
《World Journal of Gastroenterology》2012年第10期1130-1136,共7页Zhi-Wei Shen Zhen Cao Ke-Zeng You Zhong-Xian Yang Ye-Yu Xiao Xiao-Fang Cheng Yao-Wen Chen Ren-Hua Wu 
Supported by Grants from Medical Scientific Research Foundation of Guangdong Province, China, No. B2008128;National Natural Science Foundation of China, No. 30930027 and No. 60971075, in part
AIM: To evaluate the feasibility of quantifying liver choline concentrations in both normal and apoptotic rabbit livers in vivo, using 1H magnetic resonance spectroscopy (1H-MRS). METHODS: 1H-MRS was performed in 18 r...
关键词：Cell apoptosis Magnetic resonance spectroscopy Quantification CHOLINE In vivo 
Impairment of cognitive function and reduced hippocampal cholinergic activity in a rat model of chronic intermittent hypoxia被引量：1
《Neural Regeneration Research》2011年第17期1301-1305,共5页Chunling Zhao Yan Chen Chunlai Zhang Linya Lā Qian Xu 
a grant from Luzhou Medical College,No.2009
The present study established a rat model of chronic intermittent hypoxia （CIH） to simulate obstructive sleep apnea syndrome. CIH rats were evaluated for cognitive function using the Morris water maze, and neuronal ...
关键词：hypoxia brain memory dysfunction choline acetyl transferase nicotinic acetylcholinereceptor chronic intermittent hypoxia RAT neural regeneration 
Effects of cotransplantated Schwann cells and neural stem cells in a rat model of Alzheimer's disease被引量：13
《Neural Regeneration Research》2011年第4期245-251,共7页Yan Zhan Dihui Ma Yu Zhang 
the Science and Technology Development Foundation of Jilin Province, No. 200505204, 200705129
Schwann cells （SCs） are significantly better at promoting neural stem cell （NSCs） proliferation, differentiation and synaptic formation when cocultured with NSCs in vitro, compared with cultured in a single nerve ...
关键词：Schwann cells neural stem cells CO-TRANSPLANTATION ETHOLOGY glial fibrillary acidic protein S100Β choline acetyl transferase mRNA Alzheimer＇s disease 
Nicotine alpha 4 beta 2 receptor-mediated free calcium in an animal model of facial nucleus injury被引量：1
《Neural Regeneration Research》2010年第19期1500-1504,共5页Dawei Sun Wenhai Sun Yanqing Wang Fugao Zhu Rui Zhou Yanjun Wang Banghua Liu Xiuming Wan Huamin Liu 
Youth Research Fund of Qingdao University (2007)
Previous studies have demonstrated that the cholinergic system, via nicotinic receptors, regulates intracellular free calcium levels in the facial nucleus under normal physiological conditions. However, the regulation...
关键词：facial nerve injury nicotinic receptor CHOLINE CALCIUM peripheral nerve injury 
Protective effects of transplanted neural stem cells on the brain of Alzheimer’s disease rats被引量：9
《Neural Regeneration Research》2010年第11期825-832,共8页Yan Zhan Dihui Ma Yu Zhang Ming Chang Linsen Hu 
the Jilin Pro-vincial Technology Devel-opment Foundation, No. 200505204, 200705129;the Postdoctorate Founda-tion from Northeast Normal University, No. 111258000
BACKGROUND： To date, no drugs are able to halt the progression of Alzheimer＇s disease （AD）. Neural stem cells （NSCs） transplantation has been widely used to treat AD, but the mechanism of AD treatment remains un...
关键词：neural stem cells Alzheimer＇s disease choline acetyl transferase glial fibrillary acidic protein S100Β proteomics 
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