CORTICAL

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The Principle of Cortical Development and Evolution
《Neuroscience Bulletin》2025年第3期461-485,共25页Zhengang Yang 
supported by the Ministry of Science and Technology of China(STI2030-2021ZD0202300);the National Natural Science Foundation of China(32070971,32100768,32200776,and 32200792);the Shanghai Municipal Science and Technology Major Project(2018SHZDZX01)。
Human’s robust cognitive abilities,including creativity and language,are made possible,at least in large part,by evolutionary changes made to the cerebral cortex.This paper reviews the biology and evolution of mammal...
关键词：Radial glia Cortical neurogenesis Cortical gliogenesis Cortical expansion Cortical evolution FGFERK signaling SHH signaling BMP7 INTERNEURON Human-specific gene 
Cortical Morphological Networks Difer Between Gyri and Sulci
《Neuroscience Bulletin》2025年第1期46-60,共15页Qingchun Lin Suhui Jin Guole Yin Junle Li Umer Asgher Shijun Qiu Jinhui Wang 
supported by the STI 2030-Major Projects(2021ZD0200500);the National Social Science Foundation of China(20&ZD296);Key Realm R&D Program of Guangdong Province(2019B030335001).
This study explored how the human cortical folding pattern composed of convex gyri and concave sulci afected single-subject morphological brain networks,which are becoming an important method for studying the human br...
关键词：Morphological connectivity Magnetic resonance imaging Test-retest reliability Cortical folding Graph theory 
Neural Network Mechanisms Underlying General Anesthesia:Cortical and Subcortical Nuclei
《Neuroscience Bulletin》2024年第12期1995-2011,共17页Yue Hu Yun Wang Lingjing Zhang Mengqiang Luo Yingwei Wang 
supported by the National Natural Science Foundation of China(82271292,82371286,and 82101350);the Foundation of Shanghai Municipal Science and Technology Medical Innovation Research Project(23Y21900600).
General anesthesia plays a significant role in modern medicine.However,the precise mechanism of general anesthesia remains unclear,posing a key scientific challenge in anesthesiology.Advances in neuroscience technique...
关键词：General anesthesia Neural network CORTEX Subcortical nuclei CONSCIOUSNESS 
Specific and Plastic:Chandelier Cell‑to‑Axon Initial Segment Connections in Shaping Functional Cortical Network
《Neuroscience Bulletin》2024年第11期1774-1788,共15页Yanqing Qi Rui Zhao Jifeng Tian Jiangteng Lu Miao He Yilin Tai 
supported by the National Science and Technology Innovation 2030 Major Projects of China(STI2030-Major Projects-2022ZD0206500);the National Natural Science Foundation of China(32371006,32171087,82071450).
Axon initial segment(AIS)is the most excitable subcellular domain of a neuron for action potential initiation.AISs of cortical projection neurons(PNs)receive GABAergic synaptic inputs primarily from chandelier cells(C...
关键词：Axon initial segment Chandelier cell PLASTICITY 
Altered Cortical Information Interaction During Respiratory Events in Children with Obstructive Sleep Apnea-Hypopnea Syndrome
《Neuroscience Bulletin》2024年第10期1458-1470,共13页Jin Chen Minmin Lin Naikai Shi Jingxian Shen Xuchu Weng Feng Pang Jiuxing Liang 
supported by the National Natural Science Foundation of China (82001919);the Guangdong Basic and Applied Basic Research Foundation (2022A1515010050);the China Postdoctoral Science Foundation (2022M711219);the Key Realm R&D Program of Guangdong Province (2019B03035001);the Foundation of Guangdong Provincial Key Laboratory of Sensor Technology and Biomedical Instruments (2020B1212060077).
Obstructive sleep apnea-hypopnea syndrome(OSAHS)significantly impairs children's growth and cognition.This study aims to elucidate the pathophysiological mechanisms underlying OSAHS in children,with a particular focus...
关键词：Obstructive sleep apnea-hypopnea syndrome CHILDREN Respiratory events ELECTROENCEPHALOGRAM Effective connectivity-Symbolic transfer entropy 
Treadmill Exercise Reshapes Cortical Astrocytic and Neuronal Activity to Improve Motor Learning Deficits Under Chronic Alcohol Exposure
《Neuroscience Bulletin》2024年第9期1287-1298,共12页Linglin Liu Lanzhi Luo Ji-an Wei Xintong Xu Kwok-Fai So Li Zhang 
STI2030-Major Projects(2022ZD0207600);National Key Research and Development Program of China(2020YFA0113600);National Natural Science Foundation of China(U22A20301,32070955);Key Research and Development Plan of Ningxia(2022BEG01004);Guangdong Basic and Applied Basic Research Foundation(2023B1515040015).
Alcohol abuse induces various neurological disorders including motor learning deficits,possibly by affecting neuronal and astrocytic activity.Physical exercise is one effective approach to remediate synaptic loss and ...
关键词：Alcohol abuse Motor learning Dendritic spine Reactive astrocyte 
Learning Improves Peripheral Vision Via Enhanced Cortico-Cortical Communications
《Neuroscience Bulletin》2024年第7期1007-1011,共5页Yuwei Cui Xincheng Lu MiYoung Kwon Nihong Chen 
supported by the National Natural Science Foundation of China(31971031and 31930053);STI2030-Major Projects(2021ZD0203600);supported by NIH R01-EY017707.
Dear Editor,The adult human visual system is capable of reshaping its oculomotor control and sensory coding to adapt to impoverished visual inputs.When one's central vision is deprived,a spared part of the peripheral ...
关键词：VISUAL SHAPING capable 
Norepinephrine-Astrocyte Signaling Regulates Cortical State Homeostasis
《Neuroscience Bulletin》2024年第7期1021-1024,共4页Yulan Li Lixuan Li Yibei Wang Xinyi Li Zhong Chen 
supported by the National Natural Science Foundation of China(82201564,and 32300851);the Postdoctoral Science Foundation of Zhejiang Province(ZJ2022060).
Cortical states such as high and low arousal during wakefulness or rapid eye movement(REM)and non-REM(NREM)phases of sleep are fundamental biological processes that are highly conserved across species.An intricate bal...
关键词：HOMEOSTASIS NREM STASIS 
A Novel Retrograde AAV Variant for Functional Manipulation of Cortical Projection Neurons in Mice and Monkeys
《Neuroscience Bulletin》2024年第1期90-102,共13页Yefei Chen Jingyi Wang Jing Liu Jianbang Lin Yunping Lin Jinyao Nie Qi Yue Chunshan Deng Xiaofei Qi Yuantao Li Ji Dai Zhonghua Lu 
supported by Ministry of Science and Technology of China(2019YFA0903803 and 2018YFA0801404);National Natural Science Foundation of China(31871090,32000730,81961128019,and 81901397);Shenzhen Science and Technology Innovation Commission(JCYJ20190809171003698,JCYJ202103243001018,JCYJ20180507182505475,and JCYJ20180504165804015);Shenzhen Technological Research Center for Primate Translational Medicine(F-2021-Z99-504979);Youth Innovation Promotion Association(CAS 2017120);Chinese Academy of Sciences International Partnership Program(172644KYSB20170004);China Postdoctoral Science Foundation(2019M653115.);CAS Key Laboratory of Brain Connectome and Manipulation(2019DP173024);Guangdong Provincial Key Laboratory of Brain Connectome and Behavior(2017B030301017);International Science and Technology Cooperation Base of Guangdong Province(2019A050505008).
Retrograde adeno-associated viruses(AAVs)are capable of infecting the axons of projection neurons and serve as a powerful tool for the anatomical and functional characterization of neural networks.However,few retro-gr...
关键词：Retrograde AAV Capsid variant Cortical projection neuron OPTOGENETICS Monkey 
Chemogenetic Therapeutics: A Powerful Tool to Control Cortical Seizures in Non-human Primates
《Neuroscience Bulletin》2023年第10期1601-1604,共4页Lin Yang Mengdi Zhang Yi Wang Zhong Chen 
This research highlight was supported by grants from the National Key R&D Program of China(2020YFA0803902);the National Natural Science Foundation of China(82022071);the Natural Science Foundation of Zhejiang Province(LD22H310003).
The Basis for Investigating the Role of DREADDs in Epilepsy in Non-human Primates Epilepsy is one of the common neurological disorders,characterized by spontaneous and recurrent seizures.Its etiology and pathophysiolo...
关键词：EPILEPSY THERAPEUTIC seizures 
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