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作品数:111被引量:405H指数:10
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相关领域:医药卫生更多>>
相关作者:胡苹王磊李素萍王晓敏陈尚武更多>>
相关机构:吉林大学山东大学云南省第一人民医院宁夏医科大学更多>>
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相关基金:国家自然科学基金广东省自然科学基金上海市青年科技启明星计划国家重点基础研究发展计划更多>>
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DNA methyltransferase 1/miR-342-3p/Forkhead box M1 signaling axis promotes self-renewal in cervical cancer stem-like cells in vitro and nude mice models
《World Journal of Stem Cells》2025年第3期44-64,共21页Xiao-Zheng Cao Yao-Feng Zhang Yu-Wei Song Lei Yuan Hui-Li Tang Jin-Yuan Li Ye-Bei Qiu Jia-Zhi Lin Ying-Xia Ning Xiao-Yu Wang Yong Xu Shao-Qiang Lin 
Supported by Guangzhou Basic and Applied Basic Research Foundation,No.202201010121;Medical Joint Fund of Jinan University,No.YXZY2024014 and No.YXJC2022001;Hospital Achievement Transformation and Cultivation Project,No.ZH201911;the Key Discipline Project of Guangdong Province,No.2019-GDXK-0016;and the Medical Science and Technology Research Foundation of Guangdong Province,No.B2021145.
BACKGROUND Cervical cancer(CC)stem cell-like cells(CCSLCs),defined by the capacity of differentiation and self-renewal and proliferation,play a significant role in the progression of CC.However,the molecular mechanism...
关键词:DNA methyltransferase 1 Cancer stem cell Cervical cancer MiR-342-3p Forkhead box M1 
Exploring the mechanism of Xiaoaiping Injection inhibiting autophagy in prostate cancer based on proteomics
《Chinese Journal of Natural Medicines》2025年第1期64-76,共13页Qiuping Zhang Qiuju Huang Zhiping Cheng Wei Xue Shoushi Liu Yunnuo Liao Xiaolan Li Xin Chen Yaoyao Han Dan Zhu Zhiheng Su Xin Yang Zhuo Luo Hongwei Guo 
supported by Guangxi Natural Science Foundation(No.2023GXNSFDA026047);Guangxi Science and Technology Project(No.FANGKE ZY20221502);the National Natural Science Foundation of China(No.82160948);the Advanced Innovation Teams and Xinghu Scholars Program of Guangxi Medical University。
Xiaoaiping(XAP)Injection demonstrates the anti-prostate cancer(PCa)effects,yet the underlying mechanism remains unclear.This study aims to investigate the impact of XAP on PCa and elucidate its mechanism of action.PCa...
关键词:Xiaoaiping Injection AUTOPHAGY Apoptosis Forkhead box O3a Prostate cancer 
TMED3 promotes prostate cancer via FOXO1a and FOXO3a phosphorylation
《Oncology Research》2025年第1期161-169,共9页XIUWANG WEI JIANBO LIANG HUANWEN HUANG DAMING YANG XINXIN WANG XIUJIA WANG CHANGSHENG CHEN KAIQIANG LI TAISEN PANG BIN HU FENGNING WU 
supported by Guangxi Medical and Health Appropriate Technology Development and Promotion Application Project(S2022022).
Background:Transmembrane emp24 trafficking protein 3(TMED3)is associated with the development of several tumors;however,whether TMED3 regulates the progression of prostate cancer remains unclear.Materials and Methods:...
关键词:Prostate cancer Transmembrane emp24 trafficking protein 3(TMED3) forkhead box O transcription factor(FOXO) Proliferation Apoptosis 
Forkhead box O proteins:steering the course of stem cell fate
《Cell Regeneration》2024年第1期315-337,共23页Mengdi Cheng Yujie Nie Min Song Fulin Chen Yuan Yu 
National Natural Science Foundation of China(31900330);Natural Science Basic Research Plan in Shaanxi Province of China(2024JC-YBMS-182).
Stem cells are pivotal players in the intricate dance of embryonic development,tissue maintenance,and regenera-tion.Their behavior is delicately balanced between maintaining their pluripotency and differentiating as n...
关键词:Stem cell fate SELF-RENEWAL QUIESCENCE Differentiation FOXO 
Autocrine IL-8 Contributes to Propionibacterium Acnes-induced Proliferation and Differentiation of HaCaT Cells via AKT/FOXO1/Autophagy
《Current Medical Science》2024年第5期1058-1065,共8页Xiu-qin YU Jin-zhu MAO Shu-yun YANG Lu WANG Chang-zhi YANG Lei HUANG Qi-hong QIAN Ting-ting ZHU 
supported by the National Natural Science Foundation of China(No.82103756).
Objective Proprionibacterium acnes(P.acnes)-induced inflammatory responses,proliferation and differentiation of keratinocytes contribute to the progression of acne vulgaris(AV).P.acnes was found to enhance the product...
关键词:acne vulgaris Proprionibacterium acnes KERATINOCYTE INTERLEUKIN-8 C-X-C motif chemokine receptor 2 protein kinase B forkhead box O1 AUTOPHAGY 
Forkhead box K1 deficiency alleviates ischemia-reperfusion-induced acute kidney injury
《China Medical Abstracts(Internal Medicine)》2024年第3期176-177,共2页LI Chen 
Objective To investigate the effect and mechanism of forkhead box K1 (FOXK1) in acute kidney injury(AKI),and to provide new ideas and targets for preventing and treating AKI.Methods Three models of AKI were establishe...
关键词:C57BL/6 ISCHEMIA REPERFUSION 
FOXO1 reshapes neutrophils to aggravate acute brain damage and promote late depression after traumatic brain injury被引量:2
《Military Medical Research》2024年第4期521-542,共22页Mi Zhou Yang-Wu-Yue Liu Yu-Hang He Jing-Yu Zhang Hao Guo Hao Wang Jia-Kui Ren Yi-Xun Su Teng Yang Jia-Bo Li Wen-Hui He Peng-Jiao Ma Man-Tian Mi Shuang-Shuang Dai 
This work was supported by the National Natural Science Foundation of China(82071779 and 81901626);the Science Fund for Creative Research Groups of Chongqing Municipal Education Commission of China,the grants from the Talent Foundation of Army Medical University(to Shuang-Shuang Dai);the Scientific Research Grant(ALJ22J003);the Chongqing Natural Science Foundation of China(CSTB2022NSCQ-MSX0177).
Background:Neutrophils are traditionally viewed as first responders but have a short onset of action in response to traumatic brain injury(TBI).However,the heterogeneity,multifunctionality,and time-dependent modulatio...
关键词:Traumatic brain injury(TBI) NEUTROPHIL Forkhead box protein O1(FOXO1) Acute stage Chronic stage 
Self-assembly of differentiated dental pulp stem cells facilitates spheroid human dental organoid formation and prevascularization被引量:1
《World Journal of Stem Cells》2024年第3期287-304,共18页Fei Liu Jing Xiao Lei-Hui Chen Yu-Yue Pan Jun-Zhang Tian Zhi-Ren Zhang Xiao-Chun Bai 
Supported by the Science and Technology Programme of Guangzhou City,No.202201020341.
BACKGROUND The self-assembly of solid organs from stem cells has the potential to greatly expand the applicability of regenerative medicine.Stem cells can self-organise into microsized organ units,partially modelling ...
关键词:Human dental pulp stem cells Prevascularized organoids Integrated analyses ANGIOGENESIS Forkhead box protein O1 
Fangji Fuling Decoction Alleviates Sepsis by Blocking MAPK14/FOXO3A Signaling Pathway被引量:1
《Chinese Journal of Integrative Medicine》2024年第3期230-242,共13页WANG Yi CHEN Ming-qi DAI Lin-feng ZHANG Hai-dong WANG Xing 
Objective:To examine the therapeutic effect of Fangji Fuling Decoction(FFD) on sepsis through network pharmacological analysis combined with in vitro and in vivo experiments.Methods:A sepsis mouse model was constructe...
关键词:SEPSIS Fangji Fuling Decoction mitogen-activated protein kinase 14/Forkhead Box O 3A signaling pathway inflammatory response apoptosis lung injury Chinese medicine 
Comprehensive Analysis of the Role of Forkhead Box J3(FOXJ3)in Human Cancers
《Wuhan University Journal of Natural Sciences》2024年第1期74-84,共11页YANG Yang LI Yulong WANG Xiaoli 
Supported by the School Level Project of Shaanxi University of Traditional Chinese Medicine(17102032234)。
Forkhead box J3(FOXJ3)is a member of the forkhead box(Fox)family.Recently,increasing evidence has revealed the relationship between Fox family members and cancer.FOXJ3 is involved in various types of cancer,including ...
关键词:FOXJ3 CANCER genetic alteration PROGNOSIS 
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