Supported by Guangzhou Basic and Applied Basic Research Foundation,No.202201010121;Medical Joint Fund of Jinan University,No.YXZY2024014 and No.YXJC2022001;Hospital Achievement Transformation and Cultivation Project,No.ZH201911;the Key Discipline Project of Guangdong Province,No.2019-GDXK-0016;and the Medical Science and Technology Research Foundation of Guangdong Province,No.B2021145.
BACKGROUND Cervical cancer(CC)stem cell-like cells(CCSLCs),defined by the capacity of differentiation and self-renewal and proliferation,play a significant role in the progression of CC.However,the molecular mechanism...
supported by Guangxi Natural Science Foundation(No.2023GXNSFDA026047);Guangxi Science and Technology Project(No.FANGKE ZY20221502);the National Natural Science Foundation of China(No.82160948);the Advanced Innovation Teams and Xinghu Scholars Program of Guangxi Medical University。
Xiaoaiping(XAP)Injection demonstrates the anti-prostate cancer(PCa)effects,yet the underlying mechanism remains unclear.This study aims to investigate the impact of XAP on PCa and elucidate its mechanism of action.PCa...
supported by Guangxi Medical and Health Appropriate Technology Development and Promotion Application Project(S2022022).
Background:Transmembrane emp24 trafficking protein 3(TMED3)is associated with the development of several tumors;however,whether TMED3 regulates the progression of prostate cancer remains unclear.Materials and Methods:...
National Natural Science Foundation of China(31900330);Natural Science Basic Research Plan in Shaanxi Province of China(2024JC-YBMS-182).
Stem cells are pivotal players in the intricate dance of embryonic development,tissue maintenance,and regenera-tion.Their behavior is delicately balanced between maintaining their pluripotency and differentiating as n...
supported by the National Natural Science Foundation of China(No.82103756).
Objective Proprionibacterium acnes(P.acnes)-induced inflammatory responses,proliferation and differentiation of keratinocytes contribute to the progression of acne vulgaris(AV).P.acnes was found to enhance the product...
Objective To investigate the effect and mechanism of forkhead box K1 (FOXK1) in acute kidney injury(AKI),and to provide new ideas and targets for preventing and treating AKI.Methods Three models of AKI were establishe...
This work was supported by the National Natural Science Foundation of China(82071779 and 81901626);the Science Fund for Creative Research Groups of Chongqing Municipal Education Commission of China,the grants from the Talent Foundation of Army Medical University(to Shuang-Shuang Dai);the Scientific Research Grant(ALJ22J003);the Chongqing Natural Science Foundation of China(CSTB2022NSCQ-MSX0177).
Background:Neutrophils are traditionally viewed as first responders but have a short onset of action in response to traumatic brain injury(TBI).However,the heterogeneity,multifunctionality,and time-dependent modulatio...
Supported by the Science and Technology Programme of Guangzhou City,No.202201020341.
BACKGROUND The self-assembly of solid organs from stem cells has the potential to greatly expand the applicability of regenerative medicine.Stem cells can self-organise into microsized organ units,partially modelling ...
Objective:To examine the therapeutic effect of Fangji Fuling Decoction(FFD) on sepsis through network pharmacological analysis combined with in vitro and in vivo experiments.Methods:A sepsis mouse model was constructe...
Supported by the School Level Project of Shaanxi University of Traditional Chinese Medicine(17102032234)。
Forkhead box J3(FOXJ3)is a member of the forkhead box(Fox)family.Recently,increasing evidence has revealed the relationship between Fox family members and cancer.FOXJ3 is involved in various types of cancer,including ...