云南高校图书馆联盟文献共享服务平台- HEU

HEU: 作品数：52被引量：91H指数：6; 导出分析报告; 相关领域：核科学技术医药卫生更多>>; 相关作者：张小明刘国栋吴光恒王文洪卢斌更多>>; 相关机构：哈尔滨工程大学河北工业大学中国科学院中南大学更多>>; 相关期刊：《中国科技成果》《环球军事》《Chinese Medical Journal》《Journal of Computational Mathematics》更多>>; 相关基金：国家自然科学基金教育部“新世纪优秀人才支持计划”河北省应用基础研究计划黑龙江省学位与研究生教育教学改革研究项目更多>>

Integrating 16S sequencing and metabolomics study on anti-rheumatic mechanisms against collagen-induced arthritis of Wantong Jingu Tablet被引量：1: 《Chinese Journal of Natural Medicines》2022年第2期120-132,共13页LI Zhao-Dong QI Fang-Yuan LI Fan; Wantong Jingu Tablet(WJT),a mixture of traditional Chinese medicine,was reported to relieve the symptoms of rheumatoid arthritis(RA),but its pharmacological mechanism was not completely understood.The aim of this stud...; 关键词：Rheumatoid arthritis 16S rDNA sequencing Metabolomics PATHOGENESIS Wantong Jingu Tablet

Effect of sustained intensive therapy with disease modifying anti-rheumatic drugs in rheumatoid arthritis:a 5-year real-world consecutive study被引量：3: 《Chinese Medical Journal》2020年第12期1397-1403,共7页Yue-Ming Cai Ru Li Hua Ye Jing He Xiao-Lin Sun Jia-Yang Jin Jia-Jia Liu Yu-Zhou Gan Xu-Jie You Jing Xu Lian-Jie Shi Gong Cheng Qing-Wen Wang Zhan-Guo Li; This study was supported by the grants from the National Natural Science Foundation of China(Nos.81701598 and 31240023);Beijing Municipal Science and Technology Projects(Nos.Z171100000417007 and Z191100006619110).; Background:Intensive therapy with disease modifying anti-rheumatic drugs(DMARDs)has been reported to improve the outcomes of rheumatoid arthritis(RA).However,real-world study on the effect of intensive therapy on RA s...; 关键词：Rheumatoid arthritis REMISSION Sustained intensive therapy Cohort study

Clinical deep remission and related factors in a large cohort of patients with rheumatoid arthritis被引量：9: 《Chinese Medical Journal》2019年第9期1009-1014,共6页Jia-Jia Liu Ru Li Yu-Zhou Gan Rui-Jun Zhang Jing Li Yue-Ming Cai Jin-Xia Zhao Hua Liao Jing Xu Lian-Jie Shi Ji Li Sheng-Guang Li Xiao-Lin Sun Jing He Xu Liu Hua Ye Zhan-Guo Li; the grants from the National Natural Science Foundation of China (No.31530020 and No.81401329);Beijing Sci-Tech Program (No.Z171100000417007).; Background:Clinical remission is the treatment target in rheumatoid arthritis (RA).This study aimed to investigate clinical remission and related factors in a large cohort of patients with RA.Methods:This study compos...; 关键词：RHEUMATOID ARTHRITIS REMISSION Sustained Intensive Disease MODIFYING anti-rheumatic drug

Anti-rheumatoid arthritic effect of volatile components in notopterygium incisum in rats via anti-inflammatory and anti-angiogenic activities被引量：6: 《Chinese Journal of Natural Medicines》2018年第12期926-935,共10页BI Jian-Ping LI PING XU Xi-Xi WANG Ting LI Fei; supported by the National Natural Science Foundation of China(No.81760745);Major Research Plan of Shandong Province(No.2016GSF202041);Yunnan Provincial Department of Education Research Fund(No.2017ZDX230);Yunnan Innovation Team of Application Research on TCM Theory of Prevention Disease in Yunnan University of TCM(No.2017HC011); Notopterygium incisum(QH) has been used for the treatment of rheumatoid arthritis(RA), and volatile oils may be its mainly bioactive constituents. The present study was designed to analyze the volatile compounds in QH...; 关键词：NOTOPTERYGIUM incisum Volatile oil Adjuvant-induced ARTHRITIS NO production Endothelial tube formation

MCNP Simulation of Physics Parameters of Dispersion Fuels for Conversion of NIRR-1 to LEU: 《World Journal of Nuclear Science and Technology》2018年第2期23-29,共7页Kola Ibikunle Umar Sadiq Yakubu Viva Ibrahim Sunday Adesunloye Jonah; The Nigeria Research Reactor-1 (NIRR-1) is one of the Commercial Miniature Neutron Source Reactors (MNSRs) sited outside China and scheduled for conversion under the auspices of Reduced Enrichment for Research and Tes...; 关键词：NEUTRONICS Data HEU to LEU CONVERSION MNS Reactors DISPERSION Fuels MCNP

Blood glucose changes surrounding initiation of tumor-necrosis factor inhibitors and conventional disease-modifying anti-rheumatic drugs in veterans with rheumatoid arthritis被引量：10: 《World Journal of Diabetes》2018年第2期53-58,共6页Patrick R Wood Evan Manning Joshua F Baker Bryant England Lisa Davis Grant W Cannon Ted R Mikuls Liron Caplan; Supported by VA HSR&D MERIT Award IIR,No.14-048-3 for Dr Caplan;supported by a VA GME Enhancement Award; AIM To determine the scope of acute hypoglycemic effects for certain anti-rheumatic medications in a large retrospective observational study. METHODS Patients enrolled in the Veterans Affairs Rheumatoid Arthritis (VAR...; 关键词：Disease modifying anti-rheumatic drugs Drug toxicity GLUCOCORTICOIDS Rheumatoid arthritis TUMOR NECROSIS factor inhibitors

Performance of QuantiFERON(R)-TB Gold In-Tube assay in children receiving disease modifying anti-rheumatic drugs: 《World Journal of Pediatrics》2017年第5期472-478,共7页Francesca Gabriele Maria Trachana Maria Simitsopoulou Polixeni Pratsidou-Gertsi Elias Iosifidiso Zoi Dorothea Pana Emmanuel Roilides; Background:To evaluate the performance of theQuantiferon(R)-TB Gold In-Tube (QFT-IT) interferon (IFN)-7 assay for the detection of latent tuberculosis infection (LTBI)in children receiving anti-rheumatic treatment in ...; 关键词：anti-tumor necrosis factor-α interferon-γ release ASSAY latent tuberculosis RHEUMATIC DISEASE TUBERCULIN

Iguratimod, a Disease-Modifying Anti-Rheumatic Drug, Inhibits Osteoclastogenesis and Bone Resorption through Suppression of the Nuclear Factor of Activated T Cells Signaling Pathway: 《Open Journal of Rheumatology and Autoimmune Diseases》2016年第4期106-119,共14页Jun Shiota Hidetoshi Murao Akihiko Miura Masaaki Mikami Keiichi Tanaka; Introduction: The aim of this study was to observe an inhibition of bone resorption and osteoclastogenesis by iguratimod (IGU, T-614), a disease-modifying anti-rheumatic drug, using adjuvant-induced arthritis (AIA) ra...; 关键词：Bone Resorption IGURATIMOD NFATc1 OSTEOCLAST Rheumatoid Arthritis

Anti-rheumatic Drug Iguratimod(T-614) Alleviates Cancer-induced Bone Destruction via Down-regulating Interleukin-6 Production in a Nuclear Factor-κB-dependent Manner被引量：4: 《Journal of Huazhong University of Science and Technology(Medical Sciences)》2016年第5期691-699,共9页孙越叶达伟张鹏吴颖星王邦彦彭广于世英; supported by grants from the National Natural Science Foundation of China(Nos.81372852 and 81202095); Cytokines are believed to be involved in a “vicious circle” of progressive interactions in bone metastasis. Iguratimod is a novel anti-rheumatic drug which is reported to have the capability of anti-cytokines. In th...; 关键词：rheumatic T-614 Interleukin invasion regulating cytometry metastasis manner suppression destruction

In Silico Investigation of Agonist Activity of a Structurally Diverse Set of Drugs to hPXR Using HM-BSM and HM-PNN: 《Journal of Huazhong University of Science and Technology(Medical Sciences)》2016年第3期463-468,共6页张一鸣常美佳杨旭曙韩晓; supported by grants from the Natural Science Research Project of Institution of Higher Education of Jiangsu Province(No.11KJB180006);National Natural Science Foundation of China(No.21277074 and No.81302458); The human pregnane X receptor（hPXR） plays a critical role in the metabolism, transport and clearance of xenobiotics in the liver and intestine. The hPXR can be activated by a structurally diverse of drugs to initiat...; 关键词：human pregnane X receptor agonist activity heuristic method-Best Subset Modeling heu ristic method-Polynomial Neural Networks structural features quantitative structure-activity relation ship

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